Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLEKHA4
  • Mouse genes Plekha4
  • Rat genes Plekha4
  • Zfish genes si:ch211-234p6.5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plekha4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	PLEKHA4	IDA		Human	PMID:31091453
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	PLEKHA4	IDA		Human	PMID:31091453
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	PLEKHA4	IDA		Human	PMID:11001876
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	PLEKHA4	IDA		Human	PMID:31091453
Molecular Function	GO:0005515	protein binding	PLEKHA4	IPI	UniProtKB:Q5ZXN6	Human	PMID:29433439
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	PLEKHA4	IDA		Human	PMID:31091453
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	PLEKHA4	IMP		Human	PMID:31091453
Biological Process	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway	PLEKHA4	IMP		Human	PMID:31091453

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern