Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLEKHO1
  • Mouse genes Plekho1
  • Rat genes Plekho1
  • Zfish genes plekho1a,plekho1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plekho1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q93009	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q9HCE7	Human	PMID:20580715
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q9HCE7-2	Human	PMID:21382345
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:P62195	Human	PMID:23032291
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q9HCE7	Human	PMID:23032291
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q9HCE7-2	Human	PMID:23032291
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q93009	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:A2RU14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:O95159	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:P01375	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:P78329	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q08AM2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q12982	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q15546	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q15836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q4VAQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q5TGU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q6PL45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q7Z4F1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q86UF1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q8N609	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q8WVX3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q96LK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q9C0I4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q9H115	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q9Y228	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHO1	IPI	UniProtKB:Q93009	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Plekho1	IPI	PR:P47757	Mouse	PMID:22553210
Molecular Function	GO:0005515	protein binding	Plekho1	IPI	PR:Q9R0Q6	Mouse	PMID:22553210
Molecular Function	GO:0005515	protein binding	Plekho1	IPI	PR:Q9CVB6	Mouse	PMID:22553210
Cellular Component	GO:0036195	muscle cell projection membrane	Plekho1	IDA		Mouse	PMID:22553210
Cellular Component	GO:0032587	ruffle membrane	Plekho1	IDA		Mouse	PMID:22553210
Biological Process	GO:0072673	lamellipodium morphogenesis	Plekho1	IMP		Mouse	PMID:22553210
Biological Process	GO:0072673	lamellipodium morphogenesis	Plekho1	IDA		Mouse	PMID:22553210
Biological Process	GO:0007520	myoblast fusion	Plekho1	IDA		Mouse	PMID:22553210
Biological Process	GO:0007520	myoblast fusion	Plekho1	IMP		Mouse	PMID:22553210
Biological Process	GO:0051451	myoblast migration	Plekho1	IMP		Mouse	PMID:22553210
Biological Process	GO:0008360	regulation of cell shape	Plekho1	IMP		Mouse	PMID:22553210
Biological Process	GO:0008360	regulation of cell shape	Plekho1	IDA		Mouse	PMID:22553210
Biological Process	GO:1901739	regulation of myoblast fusion	plekho1b	IMP	ZFIN:ZDB-MRPHLNO-121120-1	Zfish	PMID:22553210

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern