Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLIN5
  • Mouse genes Plin5
  • Rat genes Plin5
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plin5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Plin5	IPI	UniProtKB:Q8BVZ1	Mouse	MGI:MGI:5559668|PMID:21148142
Molecular Function	GO:0035473	lipase binding	Plin5	IPI	UniProtKB:P54310	Mouse	MGI:MGI:5559670|PMID:19717842
Molecular Function	GO:0035473	lipase binding	Plin5	IPI	UniProtKB:Q8BJ56	Mouse	MGI:MGI:5559668|PMID:21148142
Molecular Function	GO:0035473	lipase binding	Plin5	IPI	UniProtKB:P0C548	Rat	PMID:23408028|RGD:8553342
Molecular Function	GO:0035473	lipase binding	Plin5	IPI	UniProtKB:P0C548	Rat	PMID:24303154|RGD:8553664
Molecular Function	GO:0035473	lipase binding	Plin5	IPI	UniProtKB:P15304	Rat	PMID:24303154|RGD:8553664
Molecular Function	GO:0005515	protein binding	PLIN5	IPI	UniProtKB:Q8WTS1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Plin5	IPI	UniProtKB:Q9DBL9	Mouse	MGI:MGI:5559668|PMID:21148142
Molecular Function	GO:0005515	protein binding	Plin5	IPI	UniProtKB:Q8BVZ1	Mouse	MGI:MGI:5559668|PMID:21148142
Molecular Function	GO:0005515	protein binding	Plin5	IPI	UniProtKB:Q6QA69	Rat	PMID:23408028|RGD:8553342
Cellular Component	GO:0005737	cytoplasm	Plin5	IDA		Mouse	MGI:MGI:5559670|PMID:19717842
Cellular Component	GO:0005829	cytosol	Plin5	IDA		Mouse	PMID:16571721
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PLIN5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005811	lipid droplet	PLIN5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005811	lipid droplet	Plin5	IDA		Mouse	MGI:MGI:3709110|PMID:17130488
Cellular Component	GO:0005811	lipid droplet	Plin5	IDA		Mouse	MGI:MGI:5559662|PMID:22675471
Cellular Component	GO:0005811	lipid droplet	Plin5	IDA		Mouse	MGI:MGI:5559668|PMID:21148142
Cellular Component	GO:0005811	lipid droplet	Plin5	IDA		Mouse	PMID:16571721
Cellular Component	GO:0005811	lipid droplet	Plin5	IDA		Rat	PMID:21885430|RGD:8553283
Cellular Component	GO:0005739	mitochondrion	Plin5	IDA		Rat	PMID:22127648|RGD:8553692
Biological Process	GO:0034389	lipid droplet organization	Plin5	IMP		Mouse	MGI:MGI:5440401|PMID:22532565
Biological Process	GO:0019915	lipid storage	Plin5	IDA		Mouse	MGI:MGI:5559662|PMID:22675471
Biological Process	GO:0019915	lipid storage	Plin5	IMP		Mouse	MGI:MGI:5559668|PMID:21148142
Biological Process	GO:0051646	mitochondrion localization	Plin5	IMP		Mouse	MGI:MGI:5559666|PMID:21885430
Biological Process	GO:0031999	negative regulation of fatty acid beta-oxidation	Plin5	IMP		Mouse	MGI:MGI:5440401|PMID:22532565
Biological Process	GO:0031999	negative regulation of fatty acid beta-oxidation	Plin5	IDA		Mouse	MGI:MGI:5559662|PMID:22675471
Biological Process	GO:0031999	negative regulation of fatty acid beta-oxidation	Plin5	IDA		Mouse	MGI:MGI:5559666|PMID:21885430
Biological Process	GO:0060192	negative regulation of lipase activity	Plin5	IMP		Mouse	MGI:MGI:5440401|PMID:22532565
Biological Process	GO:0050995	negative regulation of lipid catabolic process	Plin5	IDA		Mouse	MGI:MGI:5559666|PMID:21885430
Biological Process	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway	Plin5	IDA		Mouse	MGI:MGI:5559662|PMID:22675471
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	Plin5	IMP		Mouse	MGI:MGI:5440401|PMID:22532565
Biological Process	GO:0010897	negative regulation of triglyceride catabolic process	Plin5	IDA		Mouse	MGI:MGI:5559662|PMID:22675471
Biological Process	GO:0010897	negative regulation of triglyceride catabolic process	Plin5	IDA		Mouse	MGI:MGI:5476606|PMID:23345411
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	Plin5	IDA		Mouse	MGI:MGI:3709110|PMID:17130488
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	Plin5	IDA		Rat	PMID:22127648|RGD:8553692
Biological Process	GO:0060193	positive regulation of lipase activity	Plin5	IDA		Rat	PMID:23353597|RGD:8553378
Biological Process	GO:0010884	positive regulation of lipid storage	Plin5	IDA		Rat	PMID:23353597|RGD:8553378
Biological Process	GO:0010890	positive regulation of sequestering of triglyceride	Plin5	IDA		Mouse	MGI:MGI:5559662|PMID:22675471
Biological Process	GO:0010890	positive regulation of sequestering of triglyceride	Plin5	IDA		Rat	PMID:23353597|RGD:8553378
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	Plin5	IDA		Mouse	MGI:MGI:3709110|PMID:17130488
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	Plin5	IMP		Mouse	MGI:MGI:5440401|PMID:22532565
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	Plin5	IDA		Mouse	MGI:MGI:5559666|PMID:21885430

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern