Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0043008 | ATP-dependent protein binding | PLK2 | IDA | Human | PMID:23983262 | |
Molecular Function | GO:0051117 | ATPase binding | Plk2 | IPI | RGD:621594 | Rat | PMID:20802490|RGD:152995511 |
Molecular Function | GO:0032050 | clathrin heavy chain binding | Plk2 | IPI | RGD:2364 | Rat | PMID:20802490|RGD:152995511 |
Molecular Function | GO:0051020 | GTPase binding | Plk2 | IPI | RGD:2513 | Rat | PMID:20802490|RGD:152995511 |
Molecular Function | GO:0051020 | GTPase binding | Plk2 | IPI | RGD:620416 | Rat | PMID:20802490|RGD:152995511 |
Molecular Function | GO:0051020 | GTPase binding | Plk2 | IPI | RGD:727949 | Rat | PMID:20802490|RGD:152995511 |
Molecular Function | GO:0005515 | protein binding | PLK2 | IPI | UniProtKB:P06748 | Human | PMID:20352051 |
Molecular Function | GO:0005515 | protein binding | PLK2 | IPI | UniProtKB:Q9HC77 | Human | PMID:20531387 |
Molecular Function | GO:0005515 | protein binding | PLK2 | IPI | UniProtKB:Q86Y33 | Human | PMID:25416956 |
Molecular Function | GO:0005515 | protein binding | Plk2 | IPI | UniProtKB:Q9R010 | Rat | PMID:10523297|RGD:61555 |
Molecular Function | GO:0005515 | protein binding | Plk2 | IPI | UniProtKB:O35412 | Rat | PMID:18498738|RGD:8553496 |
Molecular Function | GO:0005515 | protein binding | Plk2 | IPI | RGD:708497 | Rat | PMID:18723513|RGD:7241135 |
Molecular Function | GO:0005515 | protein binding | Plk2 | IPI | RGD:71096 | Rat | PMID:20802490|RGD:152995511 |
Molecular Function | GO:0005515 | protein binding | Plk2 | IPI | UniProtKB:F1M386 | Rat | PMID:21382555|RGD:7241548 |
Molecular Function | GO:0005515 | protein binding | Plk2 | IPI | UniProtKB:O35412 | Rat | PMID:21382555|RGD:7241548 |
Molecular Function | GO:0005515 | protein binding | Plk2 | IPI | UniProtKB:P28818 | Rat | PMID:21382555|RGD:7241548 |
Molecular Function | GO:0005515 | protein binding | Plk2 | IPI | UniProtKB:Q9QUH6 | Rat | PMID:21382555|RGD:7241548 |
Molecular Function | GO:0019901 | protein kinase binding | Plk2 | IPI | RGD:2064 | Rat | PMID:20802490|RGD:152995511 |
Molecular Function | GO:0019901 | protein kinase binding | Plk2 | IPI | RGD:71015 | Rat | PMID:20802490|RGD:152995511 |
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | PLK2 | IDA | Human | PMID:19001868 | |
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | PLK2 | IDA | Human | PMID:20352051 | |
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | PLK2 | IDA | Human | PMID:20531387 | |
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | PLK2 | IDA | Human | PMID:23983262 | |
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | Plk2 | IDA | Mouse | MGI:MGI:5306318|PMID:12897130 | |
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | Plk2 | IDA | Rat | PMID:18498738|RGD:8553496 | |
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | Plk2 | IDA | Rat | PMID:21382555|RGD:7241548 | |
Molecular Function | GO:0044877 | protein-containing complex binding | Plk2 | IPI | RGD:708497 | Rat | PMID:18723513|RGD:7241135 |
Cellular Component | GO:0005814 | centriole | PLK2 | IDA | Human | PMID:19001868 | |
Cellular Component | GO:0005813 | centrosome | PLK2 | IDA | Human | PMID:15242618 | |
Cellular Component | GO:0000785 | chromatin | Plk2 | IDA | Mouse | PMID:22854038 | |
Cellular Component | GO:0005737 | cytoplasm | PLK2 | IDA | Human | PMID:23983262 | |
Cellular Component | GO:0030425 | dendrite | Plk2 | IDA | Rat | PMID:10523297|RGD:61555 | |
Cellular Component | GO:0045202 | synapse | Plk2 | IDA | Rat | PMID:20802490|RGD:152995511 | |
Biological Process | GO:0000082 | G1/S transition of mitotic cell cycle | PLK2 | IMP | Human | PMID:15242618 | |
Biological Process | GO:0060292 | long-term synaptic depression | Plk2 | IDA | Rat | PMID:21382555|RGD:7241548 | |
Biological Process | GO:0060291 | long-term synaptic potentiation | Plk2 | IDA | Rat | PMID:21382555|RGD:7241548 | |
Biological Process | GO:0007613 | memory | Plk2 | IMP | Mouse | MGI:MGI:5140682|PMID:21382555 | |
Biological Process | GO:0000278 | mitotic cell cycle | Plk2 | IMP | MGI:MGI:2678106 | Mouse | PMID:12972611 |
Biological Process | GO:0007052 | mitotic spindle organization | PLK2 | IDA | Human | PMID:19001868 | |
Biological Process | GO:0007052 | mitotic spindle organization | Plk2 | IMP | Mouse | MGI:MGI:5306318|PMID:12897130 | |
Biological Process | GO:0016525 | negative regulation of angiogenesis | Plk2 | IMP | Mouse | MGI:MGI:5766647|PMID:26934179 | |
Biological Process | GO:0043066 | negative regulation of apoptotic process | Plk2 | IMP | Mouse | PMID:12897130 | |
Biological Process | GO:0071866 | negative regulation of apoptotic process in bone marrow cell | Plk2 | IMP | Mouse | MGI:MGI:6120300|PMID:27908889 | |
Biological Process | GO:2000773 | negative regulation of cellular senescence | Plk2 | IMP | Mouse | MGI:MGI:6120300|PMID:27908889 | |
Biological Process | GO:0061000 | negative regulation of dendritic spine development | Plk2 | IMP | Rat | PMID:18723513|RGD:7241135 | |
Biological Process | GO:0090394 | negative regulation of excitatory postsynaptic potential | Plk2 | IMP | Rat | PMID:20802490|RGD:152995511 | |
Biological Process | GO:0032091 | negative regulation of protein binding | Plk2 | IMP | Rat | PMID:20802490|RGD:152995511 | |
Biological Process | GO:2000009 | negative regulation of protein localization to cell surface | Plk2 | IMP | Rat | PMID:20802490|RGD:152995511 | |
Biological Process | GO:0018105 | peptidyl-serine phosphorylation | PLK2 | IDA | Human | PMID:23983262 | |
Biological Process | GO:0010508 | positive regulation of autophagy | PLK2 | IDA | Human | PMID:23983262 | |
Biological Process | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis | Plk2 | IMP | Mouse | MGI:MGI:6120300|PMID:27908889 | |
Biological Process | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | PLK2 | HMP | Human | PMID:12761501 | |
Biological Process | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | Plk2 | IMP | Rat | PMID:18723513|RGD:7241135 | |
Biological Process | GO:0032092 | positive regulation of protein binding | Plk2 | IDA | Rat | PMID:18723513|RGD:7241135 | |
Biological Process | GO:0045732 | positive regulation of protein catabolic process | PLK2 | IDA | Human | PMID:23983262 | |
Biological Process | GO:0002092 | positive regulation of receptor internalization | Plk2 | IMP | Rat | PMID:20802490|RGD:152995511 | |
Biological Process | GO:0006468 | protein phosphorylation | PLK2 | IDA | Human | PMID:20352051 | |
Biological Process | GO:0006468 | protein phosphorylation | Plk2 | IDA | Mouse | MGI:MGI:5306318|PMID:12897130 | |
Biological Process | GO:0006468 | protein phosphorylation | Plk2 | IDA | Rat | PMID:21382555|RGD:7241548 | |
Biological Process | GO:0032486 | Rap protein signal transduction | Plk2 | IDA | Rat | PMID:21382555|RGD:7241548 | |
Biological Process | GO:0007265 | Ras protein signal transduction | Plk2 | IDA | Rat | PMID:21382555|RGD:7241548 | |
Biological Process | GO:0046599 | regulation of centriole replication | PLK2 | IMP | Human | PMID:15242618 | |
Biological Process | GO:0046599 | regulation of centriole replication | PLK2 | IDA | Human | PMID:19001868 | |
Biological Process | GO:0046599 | regulation of centriole replication | PLK2 | IDA | Human | PMID:20352051 | |
Biological Process | GO:0046599 | regulation of centriole replication | PLK2 | IDA | Human | PMID:20531387 | |
Biological Process | GO:0048167 | regulation of synaptic plasticity | Plk2 | IMP | Mouse | MGI:MGI:5140682|PMID:21382555 | |
Biological Process | GO:0048167 | regulation of synaptic plasticity | Plk2 | IMP | Rat | PMID:18498738|RGD:8553496 | |
Biological Process | GO:0048167 | regulation of synaptic plasticity | Plk2 | IDA | Rat | PMID:21382555|RGD:7241548 | |
Biological Process | GO:0002040 | sprouting angiogenesis | plk2b | IMP | ZFIN:ZDB-MRPHLNO-151125-1 | Zfish | PMID:26004360 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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