Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLK5
  • Mouse genes Plk5
  • Rat genes Plk5
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plk5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0005737	cytoplasm	PLK5	IDA		Human	PMID:21245385
Cellular Component	GO:0005730	nucleolus	Plk5	IDA		Mouse	MGI:MGI:5009782|PMID:20100802
Biological Process	GO:0071363	cellular response to growth factor stimulus	PLK5	IDA		Human	PMID:21245385
Biological Process	GO:0002357	defense response to tumor cell	PLK5	IDA		Human	PMID:21245385
Biological Process	GO:0002357	defense response to tumor cell	Plk5	IDA		Mouse	MGI:MGI:4946977|PMID:21245385
Biological Process	GO:0006974	DNA damage response	Plk5	IDA		Mouse	MGI:MGI:5009782|PMID:20100802
Biological Process	GO:0008285	negative regulation of cell population proliferation	Plk5	IMP		Mouse	MGI:MGI:5009782|PMID:20100802
Biological Process	GO:0008285	negative regulation of cell population proliferation	Plk5	IDA		Mouse	MGI:MGI:4946977|PMID:21245385
Biological Process	GO:0010976	positive regulation of neuron projection development	PLK5	IDA		Human	PMID:21245385
Biological Process	GO:0010976	positive regulation of neuron projection development	Plk5	IDA		Mouse	MGI:MGI:4946977|PMID:21245385
Biological Process	GO:0042981	regulation of apoptotic process	PLK5	IMP		Human	PMID:21245385
Biological Process	GO:0042981	regulation of apoptotic process	Plk5	IMP		Mouse	MGI:MGI:4946977|PMID:21245385
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	PLK5	IMP		Human	PMID:21245385
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	Plk5	IMP		Mouse	MGI:MGI:5009782|PMID:20100802
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	Plk5	IMP		Mouse	MGI:MGI:4946977|PMID:21245385

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern