Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLOD3
  • Mouse genes Plod3
  • Rat genes Plod3
  • Zfish genes plod3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plod3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046872	metal ion binding	PLOD3	EXP		Human	PMID:30089812
Molecular Function	GO:0050211	procollagen galactosyltransferase activity	PLOD3	IMP		Human	PMID:18298658
Molecular Function	GO:0033823	procollagen glucosyltransferase activity	PLOD3	IMP		Human	PMID:10934207
Molecular Function	GO:0033823	procollagen glucosyltransferase activity	PLOD3	IMP		Human	PMID:18298658
Molecular Function	GO:0033823	procollagen glucosyltransferase activity	Plod3	IDA		Mouse	MGI:MGI:6202004|PMID:16447251
Molecular Function	GO:0033823	procollagen glucosyltransferase activity	Plod3	IDA		Mouse	PMID:16467571
Molecular Function	GO:0033823	procollagen glucosyltransferase activity	Plod3	IDA		Mouse	PMID:27435297
Molecular Function	GO:0008475	procollagen-lysine 5-dioxygenase activity	PLOD3	IMP		Human	PMID:10934207
Molecular Function	GO:0008475	procollagen-lysine 5-dioxygenase activity	PLOD3	IMP		Human	PMID:18298658
Molecular Function	GO:0008475	procollagen-lysine 5-dioxygenase activity	PLOD3	IDA		Human	PMID:9582318
Molecular Function	GO:0008475	procollagen-lysine 5-dioxygenase activity	PLOD3	IDA		Human	PMID:9724729
Molecular Function	GO:0008475	procollagen-lysine 5-dioxygenase activity	Plod3	IDA		Mouse	MGI:MGI:6202004|PMID:16447251
Molecular Function	GO:0008475	procollagen-lysine 5-dioxygenase activity	Plod3	IDA		Mouse	PMID:16467571
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q96KQ7	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q9BQY4	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:A2ABF9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q5JST6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q96QF0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q5JST6	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q96KQ7	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q96QF0-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q96KQ7	Human	PMID:26028330
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q5JST6	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q96QF0	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q5JST6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:O15037	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:O60504	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:P38432	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q15742	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q53GL6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q5JST6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q6Q6R5-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q6ZNG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q7L273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q96JM7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q96KQ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q9UHH9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLOD3	IPI	UniProtKB:Q9UMD9	Human	PMID:32296183
Molecular Function	GO:0036094	small molecule binding	PLOD3	EXP		Human	PMID:30089812
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Plod3	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Plod3	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Plod3	IDA		Mouse	PMID:27435297
Cellular Component	GO:0005783	endoplasmic reticulum	PLOD3	IDA		Human	PMID:10934207
Cellular Component	GO:0005783	endoplasmic reticulum	Plod3	IDA		Mouse	MGI:MGI:6202004|PMID:16447251
Cellular Component	GO:0070062	extracellular exosome	PLOD3	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PLOD3	HDA		Human	PMID:19199708
Cellular Component	GO:0005615	extracellular space	Plod3	IDA		Mouse	MGI:MGI:6202004|PMID:16447251
Cellular Component	GO:0005794	Golgi apparatus	PLOD3	IDA		Human	PMID:10934207
Cellular Component	GO:0005794	Golgi apparatus	PLOD3	IDA		Human	PMID:27435297
Cellular Component	GO:0005802	trans-Golgi network	Plod3	IDA		Mouse	PMID:27435297
Biological Process	GO:0070831	basement membrane assembly	Plod3	IMP	MGI:MGI:3620601	Mouse	PMID:16467571
Biological Process	GO:0070831	basement membrane assembly	Plod3	IMP	MGI:MGI:3620603	Mouse	PMID:16467571
Biological Process	GO:0070831	basement membrane assembly	Plod3	IMP	MGI:MGI:3620600	Mouse	PMID:16467571
Biological Process	GO:0032870	cellular response to hormone stimulus	Plod3	IEP		Rat	PMID:15817667|RGD:2314536
Biological Process	GO:0030199	collagen fibril organization	Plod3	IMP	MGI:MGI:3620600	Mouse	PMID:16467571
Biological Process	GO:0030199	collagen fibril organization	Plod3	IMP	MGI:MGI:3620603	Mouse	PMID:16467571
Biological Process	GO:0032963	collagen metabolic process	Plod3	IMP		Mouse	PMID:27435297
Biological Process	GO:0001886	endothelial cell morphogenesis	Plod3	IMP	MGI:MGI:3620601	Mouse	PMID:16467571
Biological Process	GO:0001886	endothelial cell morphogenesis	Plod3	IMP	MGI:MGI:3620600	Mouse	PMID:16467571
Biological Process	GO:0048730	epidermis morphogenesis	Plod3	IMP	MGI:MGI:3620603	Mouse	PMID:16467571
Biological Process	GO:0046947	hydroxylysine biosynthetic process	Plod3	IDA		Mouse	MGI:MGI:6202004|PMID:16447251
Biological Process	GO:0001701	in utero embryonic development	Plod3	IMP	MGI:MGI:3620600	Mouse	PMID:16467571
Biological Process	GO:0001701	in utero embryonic development	Plod3	IMP	MGI:MGI:3620601	Mouse	PMID:16467571
Biological Process	GO:0060425	lung morphogenesis	Plod3	IMP	MGI:MGI:3620603	Mouse	PMID:16467571
Biological Process	GO:0008045	motor neuron axon guidance	plod3	IMP	ZFIN:ZDB-GENO-980202-881	Zfish	PMID:16731508
Biological Process	GO:0008045	motor neuron axon guidance	plod3	IMP	ZFIN:ZDB-GENO-080919-2	Zfish	PMID:12482713
Biological Process	GO:0008045	motor neuron axon guidance	plod3	IMP	ZFIN:ZDB-GENO-980202-1211	Zfish	PMID:12482713
Biological Process	GO:0008045	motor neuron axon guidance	plod3	IMP	ZFIN:ZDB-GENO-080919-1	Zfish	PMID:12482713
Biological Process	GO:0008045	motor neuron axon guidance	plod3	IMP	ZFIN:ZDB-GENO-980202-1211	Zfish	PMID:10393124
Biological Process	GO:0001755	neural crest cell migration	plod3	IMP	ZFIN:ZDB-GENO-980202-1211	Zfish	PMID:23349938
Biological Process	GO:0021915	neural tube development	Plod3	IMP	MGI:MGI:3620601	Mouse	PMID:16467571
Biological Process	GO:0021915	neural tube development	Plod3	IMP	MGI:MGI:3620600	Mouse	PMID:16467571
Biological Process	GO:0017185	peptidyl-lysine hydroxylation	PLOD3	IMP		Human	PMID:10934207
Biological Process	GO:0017185	peptidyl-lysine hydroxylation	PLOD3	IMP		Human	PMID:18298658
Biological Process	GO:0017185	peptidyl-lysine hydroxylation	PLOD3	IDA		Human	PMID:9582318
Biological Process	GO:0017185	peptidyl-lysine hydroxylation	PLOD3	IDA		Human	PMID:9724729
Biological Process	GO:0017185	peptidyl-lysine hydroxylation	Plod3	IDA		Mouse	MGI:MGI:6202004|PMID:16447251
Biological Process	GO:0017185	peptidyl-lysine hydroxylation	Plod3	IMP		Mouse	PMID:27435297
Biological Process	GO:0008104	protein localization	Plod3	IMP	MGI:MGI:3620601	Mouse	PMID:16467571
Biological Process	GO:0008104	protein localization	Plod3	IMP	MGI:MGI:3620600	Mouse	PMID:16467571
Biological Process	GO:0006493	protein O-linked glycosylation	PLOD3	IMP		Human	PMID:10934207
Biological Process	GO:0051238	sequestering of metal ion	PLOD3	EXP		Human	PMID:30089812
Biological Process	GO:0042311	vasodilation	Plod3	IMP	MGI:MGI:3620600	Mouse	PMID:16467571
Biological Process	GO:0042311	vasodilation	Plod3	IMP	MGI:MGI:3620601	Mouse	PMID:16467571

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern