Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLPP3
  • Mouse genes Plpp3
  • Rat genes Plpp3
  • Zfish genes plpp3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plpp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0106235	ceramide-1-phosphate phosphatase activity	PLPP3	IDA		Human	PMID:9705349
Molecular Function	GO:0005178	integrin binding	PLPP3	IDA		Human	PMID:12660161
Molecular Function	GO:0005178	integrin binding	Plpp3	IDA		Mouse	PMID:16099422
Molecular Function	GO:0042577	lipid phosphatase activity	Plpp3	IMP	MGI:MGI:2674217	Mouse	PMID:12925589
Molecular Function	GO:0008195	phosphatidate phosphatase activity	PLPP3	IDA		Human	PMID:9305923
Molecular Function	GO:0008195	phosphatidate phosphatase activity	PLPP3	IDA		Human	PMID:9705349
Molecular Function	GO:0005515	protein binding	PLPP3	IPI	UniProtKB:O60716	Human	PMID:20123964
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	PLPP3	IDA		Human	PMID:9305923
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	PLPP3	IDA		Human	PMID:9705349
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	Plpp3	IMP	MGI:MGI:2176173,MGI:MGI:3723633	Mouse	PMID:21319224
Cellular Component	GO:0016323	basolateral plasma membrane	PLPP3	IDA		Human	PMID:14527693
Cellular Component	GO:0070971	endoplasmic reticulum exit site	PLPP3	IDA		Human	PMID:23591818
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Plpp3	IDA		Rat	PMID:8939937|RGD:632577
Cellular Component	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	PLPP3	IDA		Human	PMID:23591818
Cellular Component	GO:0005794	Golgi apparatus	PLPP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	PLPP3	IDA		Human	PMID:23591818
Cellular Component	GO:0016020	membrane	PLPP3	IDA		Human	PMID:9305923
Cellular Component	GO:0016020	membrane	PLPP3	IDA		Human	PMID:9705349
Cellular Component	GO:0045121	membrane raft	PLPP3	IDA		Human	PMID:17005594
Cellular Component	GO:0005886	plasma membrane	Plpp3	IDA		Mouse	PMID:21319224
Cellular Component	GO:0005802	trans-Golgi network	PLPP3	IDA		Human	PMID:23591818
Biological Process	GO:0060020	Bergmann glial cell differentiation	Plpp3	IMP	MGI:MGI:2176173,MGI:MGI:3723633	Mouse	PMID:21319224
Biological Process	GO:0001568	blood vessel development	Plpp3	IMP	MGI:MGI:2674217	Mouse	PMID:12925589
Biological Process	GO:0007155	cell adhesion	Plpp3	IDA		Mouse	PMID:16099422
Biological Process	GO:0098609	cell-cell adhesion	Plpp3	IDA		Mouse	PMID:16099422
Biological Process	GO:0033631	cell-cell adhesion mediated by integrin	PLPP3	IDA		Human	PMID:12660161
Biological Process	GO:0006672	ceramide metabolic process	PLPP3	IDA		Human	PMID:9305923
Biological Process	GO:0006672	ceramide metabolic process	PLPP3	IDA		Human	PMID:9705349
Biological Process	GO:0001702	gastrulation with mouth forming second	Plpp3	IMP	MGI:MGI:2674217	Mouse	PMID:12925589
Biological Process	GO:0034109	homotypic cell-cell adhesion	PLPP3	IDA		Human	PMID:20123964
Biological Process	GO:0007229	integrin-mediated signaling pathway	PLPP3	IDA		Human	PMID:12660161
Biological Process	GO:0001933	negative regulation of protein phosphorylation	PLPP3	IDA		Human	PMID:20123964
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Plpp3	IDA		Mouse	MGI:MGI:4820698|PMID:20123964
Biological Process	GO:0046839	phospholipid dephosphorylation	PLPP3	IDA		Human	PMID:9305923
Biological Process	GO:0046839	phospholipid dephosphorylation	PLPP3	IDA		Human	PMID:9705349
Biological Process	GO:0006644	phospholipid metabolic process	PLPP3	IDA		Human	PMID:9305923
Biological Process	GO:0006644	phospholipid metabolic process	PLPP3	IDA		Human	PMID:9705349
Biological Process	GO:0006644	phospholipid metabolic process	Plpp3	IMP	MGI:MGI:2674217	Mouse	PMID:12925589
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	PLPP3	IMP		Human	PMID:20123964
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	PLPP3	IDA		Human	PMID:20123964
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Plpp3	IDA		Mouse	MGI:MGI:4820698|PMID:20123964
Biological Process	GO:0010595	positive regulation of endothelial cell migration	PLPP3	IMP		Human	PMID:20123964
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Plpp3	IDA		Mouse	PMID:16099422
Biological Process	GO:0050821	protein stabilization	PLPP3	IDA		Human	PMID:20123964
Biological Process	GO:0050821	protein stabilization	Plpp3	IDA		Mouse	MGI:MGI:4820698|PMID:20123964
Biological Process	GO:1902068	regulation of sphingolipid mediated signaling pathway	Plpp3	IMP	MGI:MGI:2176173,MGI:MGI:3723633	Mouse	PMID:21319224
Biological Process	GO:0030111	regulation of Wnt signaling pathway	Plpp3	IDA		Mouse	PMID:12925589
Biological Process	GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	PLPP3	IMP		Human	PMID:23591818
Biological Process	GO:0006670	sphingosine metabolic process	PLPP3	IDA		Human	PMID:9305923
Biological Process	GO:0006670	sphingosine metabolic process	PLPP3	IDA		Human	PMID:9705349
Biological Process	GO:0042060	wound healing	PLPP3	IMP		Human	PMID:20123964

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern