Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLRG1
  • Mouse genes Plrg1
  • Rat genes Plrg1
  • Zfish genes plrg1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plrg1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PLRG1	IPI	UniProtKB:O75934	Human	PMID:20176811
Molecular Function	GO:0005515	protein binding	PLRG1	IPI	UniProtKB:Q99459	Human	PMID:20176811
Molecular Function	GO:0005515	protein binding	PLRG1	IPI	UniProtKB:Q9UMS4	Human	PMID:20176811
Molecular Function	GO:0005515	protein binding	PLRG1	IPI	UniProtKB:P52272	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	PLRG1	IPI	UniProtKB:Q99459	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	PLRG1	IPI	UniProtKB:Q9BQ65	Human	PMID:23022480
Cellular Component	GO:0071013	catalytic step 2 spliceosome	PLRG1	IDA		Human	PMID:11991638
Cellular Component	GO:0001650	fibrillar center	PLRG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031965	nuclear membrane	PLRG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	PLRG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PLRG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PLRG1	IDA		Human	PMID:28076346
Cellular Component	GO:0000974	Prp19 complex	PLRG1	IPI		Human	PMID:20176811
Cellular Component	GO:0005681	spliceosomal complex	PLRG1	IPI		Human	PMID:20176811
Cellular Component	GO:0071007	U2-type catalytic step 2 spliceosome	PLRG1	IDA		Human	PMID:28076346
Biological Process	GO:0000398	mRNA splicing, via spliceosome	PLRG1	IDA		Human	PMID:28076346
Biological Process	GO:0043066	negative regulation of apoptotic process	plrg1	IMP	ZFIN:ZDB-MRPHLNO-090610-4	Zfish	PMID:19307306
Biological Process	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	plrg1	IMP	ZFIN:ZDB-MRPHLNO-090610-4	Zfish	PMID:22952453
Biological Process	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	plrg1	IGI	ZFIN:ZDB-MRPHLNO-090610-4,ZFIN:ZDB-MRPHLNO-120919-1	Zfish	PMID:22952453
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	Plrg1	IMP	MGI:MGI:3848230	Mouse	PMID:19307306
Biological Process	GO:0034504	protein localization to nucleus	Plrg1	IMP	MGI:MGI:3848230	Mouse	PMID:19307306

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern