Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLXNA1
  • Mouse genes Plxna1
  • Rat genes Plxna1
  • Zfish genes plxna1a,plxna1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plxna1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Plxna1	IPI	UniProtKB:P97333|UniProtKB:Q99NH8	Mouse	MGI:MGI:5319714|PMID:22522930
Molecular Function	GO:0005515	protein binding	Plxna1	IPI	UniProtKB:Q8BNV8	Mouse	MGI:MGI:6092794|PMID:18287072
Molecular Function	GO:0005515	protein binding	Plxna1	IPI	PR:O35375	Mouse	PMID:10520994
Molecular Function	GO:0005515	protein binding	Plxna1	IPI	PR:Q76KF0	Mouse	PMID:14977921
Molecular Function	GO:0005515	protein binding	Plxna1	IPI	PR:P35918	Mouse	PMID:14977921
Molecular Function	GO:0005515	protein binding	Plxna1	IPI	PR:P97333	Mouse	PMID:10520994
Molecular Function	GO:0017154	semaphorin receptor activity	Plxna1	IPI	PR:O08665	Mouse	PMID:15239958
Molecular Function	GO:0017154	semaphorin receptor activity	Plxna1	IPI	PR:Q76KF0	Mouse	PMID:17145500
Molecular Function	GO:0017154	semaphorin receptor activity	Plxna1	IPI	PR:Q9WTM3	Mouse	PMID:17145500
Cellular Component	GO:0005829	cytosol	PLXNA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	PLXNA1	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	Plxna1	IDA		Mouse	PMID:11241833
Cellular Component	GO:0005654	nucleoplasm	PLXNA1	IDA		Human	GO_REF:0000052
Biological Process	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	Plxna1	IDA		Mouse	PMID:17626059
Biological Process	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	Plxna1	IGI	UniProtKB:P70208	Mouse	MGI:MGI:6389759|PMID:31690636
Biological Process	GO:1990138	neuron projection extension	Plxna1	IGI	MGI:MGI:107683	Mouse	PMID:21835343
Biological Process	GO:1990138	neuron projection extension	Plxna1	IGI	MGI:MGI:107555	Mouse	PMID:21835343
Biological Process	GO:0097485	neuron projection guidance	Plxna1	IMP	MGI:MGI:3831874	Mouse	PMID:21835343
Biological Process	GO:0021628	olfactory nerve formation	Plxna1	IGI	UniProtKB:P70208	Mouse	MGI:MGI:6389759|PMID:31690636
Biological Process	GO:0002072	optic cup morphogenesis involved in camera-type eye development	plxna1a	IMP	ZFIN:ZDB-MRPHLNO-220316-1	Zfish	PMID:33811086
Biological Process	GO:0014910	regulation of smooth muscle cell migration	Plxna1	IMP		Mouse	PMID:14977921
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxna1	IPI	PR:Q9WTM3	Mouse	MGI:MGI:3831479|PMID:17145500
Biological Process	GO:0002040	sprouting angiogenesis	plxna1b	IMP	ZFIN:ZDB-MRPHLNO-120627-2	Zfish	PMID:27506939
Biological Process	GO:0042060	wound healing	plxna1b	IMP	ZFIN:ZDB-MRPHLNO-171004-1	Zfish	PMID:27452696
Biological Process	GO:0042060	wound healing	plxna1b	IMP	ZFIN:ZDB-CRISPR-171005-1,ZFIN:ZDB-CRISPR-171005-2	Zfish	PMID:27452696
Biological Process	GO:0042060	wound healing	plxna1b	IMP	ZFIN:ZDB-MRPHLNO-170912-6	Zfish	PMID:27452696
Biological Process	GO:0042060	wound healing	plxna1b	IMP	ZFIN:ZDB-CRISPR-171005-3,ZFIN:ZDB-CRISPR-171005-4	Zfish	PMID:27452696

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern