Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLXNA3
  • Mouse genes Plxna3
  • Rat genes Plxna3
  • Zfish genes plxna3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plxna3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	plxna3	IPI	ZFIN:ZDB-GENE-070613-1	Zfish	PMID:25565389
Molecular Function	GO:0042802	identical protein binding	plxna3	IPI	ZFIN:ZDB-GENE-070613-1	Zfish	PMID:27508400
Molecular Function	GO:0005515	protein binding	PLXNA3	IPI	UniProtKB:O75081	Human	PMID:20138877
Molecular Function	GO:0017154	semaphorin receptor activity	Plxna3	IMP		Mouse	MGI:MGI:5009366|PMID:19717441
Cellular Component	GO:0016020	membrane	plxna3	IDA		Zfish	PMID:25565389
Biological Process	GO:0048675	axon extension	plxna3	IMP	ZFIN:ZDB-MRPHLNO-070613-2	Zfish	PMID:19059233
Biological Process	GO:0048675	axon extension	plxna3	IGI	ZFIN:ZDB-MRPHLNO-070613-2,ZFIN:ZDB-MRPHLNO-090811-1	Zfish	PMID:19059233
Biological Process	GO:0048846	axon extension involved in axon guidance	Plxna3	IGI	MGI:MGI:107558	Mouse	PMID:11683995
Biological Process	GO:0048846	axon extension involved in axon guidance	Plxna3	IGI	MGI:MGI:1096347	Mouse	PMID:11683995
Biological Process	GO:0007411	axon guidance	Plxna3	IMP	MGI:MGI:2386961	Mouse	PMID:11683995
Biological Process	GO:0048755	branching morphogenesis of a nerve	plxna3	IGI	ZFIN:ZDB-MRPHLNO-051129-1,ZFIN:ZDB-MRPHLNO-070613-2	Zfish	PMID:17475806
Biological Process	GO:0048755	branching morphogenesis of a nerve	plxna3	IMP	ZFIN:ZDB-MRPHLNO-070613-2	Zfish	PMID:17475806
Biological Process	GO:0048755	branching morphogenesis of a nerve	plxna3	IGI	ZFIN:ZDB-MRPHLNO-050513-4,ZFIN:ZDB-MRPHLNO-070613-2	Zfish	PMID:17475806
Biological Process	GO:0048755	branching morphogenesis of a nerve	plxna3	IMP	ZFIN:ZDB-MRPHLNO-070613-3	Zfish	PMID:17475806
Biological Process	GO:0021785	branchiomotor neuron axon guidance	Plxna3	IMP		Mouse	MGI:MGI:3822054|PMID:18804103
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	plxna3	IMP	ZFIN:ZDB-MRPHLNO-070613-2	Zfish	PMID:22542598
Biological Process	GO:0021612	facial nerve structural organization	Plxna3	IMP		Mouse	MGI:MGI:3822054|PMID:18804103
Biological Process	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	Plxna3	IGI	UniProtKB:P70206	Mouse	MGI:MGI:6389759|PMID:31690636
Biological Process	GO:0021766	hippocampus development	Plxna3	IMP	MGI:MGI:2386961	Mouse	PMID:11683995
Biological Process	GO:0008045	motor neuron axon guidance	plxna3	IMP	ZFIN:ZDB-MRPHLNO-070613-3	Zfish	PMID:17475806
Biological Process	GO:0008045	motor neuron axon guidance	plxna3	IMP	ZFIN:ZDB-GENO-071205-2	Zfish	PMID:17699608
Biological Process	GO:0008045	motor neuron axon guidance	plxna3	IMP	ZFIN:ZDB-MRPHLNO-070613-2	Zfish	PMID:23302694
Biological Process	GO:0008045	motor neuron axon guidance	plxna3	IMP	ZFIN:ZDB-MRPHLNO-071205-4	Zfish	PMID:17699608
Biological Process	GO:0008045	motor neuron axon guidance	plxna3	IMP	ZFIN:ZDB-GENO-071206-3	Zfish	PMID:17699608
Biological Process	GO:0008045	motor neuron axon guidance	plxna3	IMP	ZFIN:ZDB-GENO-071126-1	Zfish	PMID:25565389
Biological Process	GO:0008045	motor neuron axon guidance	plxna3	IMP	ZFIN:ZDB-MRPHLNO-070613-2	Zfish	PMID:17475806
Biological Process	GO:0008045	motor neuron axon guidance	plxna3	IMP	ZFIN:ZDB-GENO-071205-5	Zfish	PMID:17699608
Biological Process	GO:0008045	motor neuron axon guidance	plxna3	IGI	ZFIN:ZDB-MRPHLNO-051129-1,ZFIN:ZDB-MRPHLNO-070613-2	Zfish	PMID:17475806
Biological Process	GO:0050919	negative chemotaxis	Plxna3	IGI	MGI:MGI:1096347	Mouse	PMID:11683995
Biological Process	GO:0050919	negative chemotaxis	Plxna3	IGI	MGI:MGI:107558	Mouse	PMID:11683995
Biological Process	GO:0048843	negative regulation of axon extension involved in axon guidance	Plxna3	IGI	MGI:MGI:1096347	Mouse	PMID:11683995
Biological Process	GO:0048843	negative regulation of axon extension involved in axon guidance	Plxna3	IGI	MGI:MGI:107558	Mouse	PMID:11683995
Biological Process	GO:1990138	neuron projection extension	Plxna3	IGI	MGI:MGI:107685	Mouse	PMID:21835343
Biological Process	GO:1990138	neuron projection extension	Plxna3	IGI	MGI:MGI:107555	Mouse	PMID:21835343
Biological Process	GO:0097485	neuron projection guidance	Plxna3	IMP	MGI:MGI:2386961	Mouse	PMID:21835343
Biological Process	GO:0021628	olfactory nerve formation	Plxna3	IGI	UniProtKB:P70206	Mouse	MGI:MGI:6389759|PMID:31690636
Biological Process	GO:0051495	positive regulation of cytoskeleton organization	Plxna3	IMP		Mouse	MGI:MGI:5009366|PMID:19717441
Biological Process	GO:0021860	pyramidal neuron development	Plxna3	IMP	MGI:MGI:2386961	Mouse	PMID:11683995
Biological Process	GO:0048696	regulation of collateral sprouting in absence of injury	plxna3	IMP	ZFIN:ZDB-GENO-071126-2	Zfish	PMID:23349787
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	Plxna3	IMP		Mouse	MGI:MGI:3822054|PMID:18804103
Biological Process	GO:0021637	trigeminal nerve structural organization	Plxna3	IMP		Mouse	MGI:MGI:3822054|PMID:18804103

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern