Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLXNA4
  • Mouse genes Plxna4
  • Rat genes Plxna4
  • Zfish genes plxna4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plxna4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Plxna4	IPI	UniProtKB:O35464	Mouse	MGI:MGI:4821874|PMID:20606624
Molecular Function	GO:0005515	protein binding	Plxna4	IPI	PR:O54951	Mouse	PMID:15814794
Molecular Function	GO:0005515	protein binding	Plxna4	IPI	PR:O35464	Mouse	PMID:15814794
Molecular Function	GO:0017154	semaphorin receptor activity	Plxna4	IGI	MGI:MGI:106206	Mouse	PMID:12591607
Cellular Component	GO:0150053	cerebellar climbing fiber to Purkinje cell synapse	Plxna4	IDA		Mouse	PMID:24831527
Cellular Component	GO:0150053	cerebellar climbing fiber to Purkinje cell synapse	Plxna4	IMP		Mouse	PMID:24831527
Biological Process	GO:0021960	anterior commissure morphogenesis	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0007411	axon guidance	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0007411	axon guidance	plxna4	IGI	ZFIN:ZDB-GENO-060825-3	Zfish	PMID:15229183
Biological Process	GO:0007414	axonal defasciculation	plxna4	IGI	ZFIN:ZDB-GENO-060825-3	Zfish	PMID:15229183
Biological Process	GO:0021785	branchiomotor neuron axon guidance	Plxna4	IMP		Mouse	MGI:MGI:3822054|PMID:18804103
Biological Process	GO:0021793	chemorepulsion of branchiomotor axon	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0021602	cranial nerve morphogenesis	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0035050	embryonic heart tube development	Plxna4	IMP	MGI:MGI:1857637	Mouse	PMID:30735130
Biological Process	GO:0035050	embryonic heart tube development	Plxna4	IGI	MGI:MGI:2179061	Mouse	PMID:30735130
Biological Process	GO:0035050	embryonic heart tube development	Plxna4	IMP	MGI:MGI:2687362	Mouse	PMID:30735130
Biological Process	GO:0035050	embryonic heart tube development	Plxna4	IMP	MGI:MGI:2158947	Mouse	PMID:30735130
Biological Process	GO:0035050	embryonic heart tube development	Plxna4	IGI	MGI:MGI:105923	Mouse	PMID:30735130
Biological Process	GO:0021610	facial nerve morphogenesis	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0021612	facial nerve structural organization	Plxna4	IMP		Mouse	MGI:MGI:3822054|PMID:18804103
Biological Process	GO:0021615	glossopharyngeal nerve morphogenesis	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0099558	maintenance of synapse structure	Plxna4	IMP		Mouse	PMID:24831527
Biological Process	GO:0099558	maintenance of synapse structure	Plxna4	IDA		Mouse	PMID:24831527
Biological Process	GO:0001763	morphogenesis of a branching structure	plxna4	IMP	ZFIN:ZDB-GENO-060825-2	Zfish	PMID:15229183
Biological Process	GO:0008045	motor neuron axon guidance	Plxna4	IMP		Mouse	MGI:MGI:3822054|PMID:18804103
Biological Process	GO:0007399	nervous system development	Plxna4	IGI	MGI:MGI:107558	Mouse	PMID:12591607
Biological Process	GO:0048812	neuron projection morphogenesis	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0021784	postganglionic parasympathetic fiber development	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0048841	regulation of axon extension involved in axon guidance	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0050923	regulation of negative chemotaxis	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxna4	IGI	MGI:MGI:107558	Mouse	PMID:12591607
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxna4	IGI	MGI:MGI:106206	Mouse	PMID:12591607
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	Plxna4	IMP		Mouse	MGI:MGI:3822054|PMID:18804103
Biological Process	GO:0048485	sympathetic nervous system development	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0097492	sympathetic neuron axon guidance	Plxna4	IGI	MGI:MGI:105923	Mouse	PMID:30735130
Biological Process	GO:0021636	trigeminal nerve morphogenesis	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794
Biological Process	GO:0021637	trigeminal nerve structural organization	Plxna4	IMP		Mouse	MGI:MGI:3822054|PMID:18804103
Biological Process	GO:0021644	vagus nerve morphogenesis	Plxna4	IMP	MGI:MGI:3578655	Mouse	PMID:15814794

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern