Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLXNB2
  • Mouse genes Plxnb2
  • Rat genes Plxnb2
  • Zfish genes plxnb2a.1,plxnb2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plxnb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PLXNB2	IPI	UniProtKB:P08581	Human	PMID:15184888
Molecular Function	GO:0005515	protein binding	PLXNB2	IPI	UniProtKB:Q04912	Human	PMID:15184888
Molecular Function	GO:0005515	protein binding	PLXNB2	IPI	UniProtKB:P52198	Human	PMID:29040270
Molecular Function	GO:0005515	protein binding	PLXNB2	IPI	UniProtKB:P61587	Human	PMID:29040270
Molecular Function	GO:0005515	protein binding	PLXNB2	IPI	UniProtKB:Q92730	Human	PMID:29040270
Molecular Function	GO:0005515	protein binding	Plxnb2	IPI	UniProtKB:Q68FM7	Mouse	MGI:MGI:5508282|PMID:12123608
Molecular Function	GO:0005515	protein binding	Plxnb2	IPI	PR:O09126	Mouse	PMID:15330859
Molecular Function	GO:0017154	semaphorin receptor activity	Plxnb2	IMP		Mouse	MGI:MGI:3712712|PMID:17554007
Cellular Component	GO:0009986	cell surface	PLXNB2	HDA		Human	PMID:19581412
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Plxnb2	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Plxnb2	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	PLXNB2	HDA		Human	PMID:20458337
Cellular Component	GO:0005886	plasma membrane	Plxnb2	IDA		Mouse	MGI:MGI:5296419|PMID:21966369
Biological Process	GO:0007420	brain development	Plxnb2	IMP		Mouse	MGI:MGI:3712712|PMID:17554007
Biological Process	GO:1904861	excitatory synapse assembly	Plxnb2	IMP		Mouse	MGI:MGI:6269924|PMID:29981480
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	PLXNB2	IDA		Human	PMID:16122393
Biological Process	GO:0001843	neural tube closure	Plxnb2	IMP		Mouse	MGI:MGI:3712712|PMID:17554007
Biological Process	GO:0007405	neuroblast proliferation	Plxnb2	IMP		Mouse	MGI:MGI:3712712|PMID:17554007
Biological Process	GO:0050772	positive regulation of axonogenesis	Plxnb2	IGI	MGI:MGI:109244	Mouse	PMID:15330859
Biological Process	GO:0010976	positive regulation of neuron projection development	PLXNB2	IDA		Human	PMID:16122393
Biological Process	GO:0045727	positive regulation of translation	PLXNB2	IMP		Human	PMID:29100074
Biological Process	GO:0008360	regulation of cell shape	Plxnb2	IMP		Mouse	MGI:MGI:3712712|PMID:17554007
Biological Process	GO:0043087	regulation of GTPase activity	Plxnb2	IMP		Mouse	MGI:MGI:3712712|PMID:17554007
Biological Process	GO:2001222	regulation of neuron migration	Plxnb2	IMP		Mouse	MGI:MGI:3712712|PMID:17554007
Biological Process	GO:0001932	regulation of protein phosphorylation	Plxnb2	IMP		Mouse	MGI:MGI:3712712|PMID:17554007
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxnb2	IMP		Mouse	MGI:MGI:3712712|PMID:17554007
Biological Process	GO:0002040	sprouting angiogenesis	plxnb2a.1	IMP	ZFIN:ZDB-MRPHLNO-100510-6	Zfish	PMID:19422817
Biological Process	GO:0002040	sprouting angiogenesis	plxnb2a.1	IGI	ZFIN:ZDB-GENO-110408-5,ZFIN:ZDB-MRPHLNO-100510-6	Zfish	PMID:19422817

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern