Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLXNB3
  • Mouse genes Plxnb3
  • Rat genes Plxnb3
  • Zfish genes plxnb3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plxnb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0098632	cell-cell adhesion mediator activity	PLXNB3	IPI	UniProtKB:Q9ULL4	Human	PMID:16122393
Molecular Function	GO:0005515	protein binding	PLXNB3	IPI	UniProtKB:P08581	Human	PMID:15184888
Molecular Function	GO:0005515	protein binding	PLXNB3	IPI	UniProtKB:Q04912	Human	PMID:15184888
Molecular Function	GO:0005515	protein binding	PLXNB3	IPI	UniProtKB:Q99578	Human	PMID:16122393
Molecular Function	GO:0005515	protein binding	PLXNB3	IPI	UniProtKB:Q9ULL4	Human	PMID:16122393
Molecular Function	GO:0005515	protein binding	PLXNB3	IPI	UniProtKB:Q16658	Human	PMID:21706053
Molecular Function	GO:0005515	protein binding	Plxnb3	IPI	UniProtKB:Q61553	Mouse	MGI:MGI:5487516|PMID:21706053
Molecular Function	GO:0005515	protein binding	Plxnb3	IPI	UniProtKB:Q6RUV5	Mouse	MGI:MGI:5532914|PMID:20696765
Molecular Function	GO:0019904	protein domain specific binding	PLXNB3	IPI	UniProtKB:Q62217	Human	PMID:15218527
Molecular Function	GO:0051022	Rho GDP-dissociation inhibitor binding	Plxnb3	IPI	UniProtKB:Q99PT1	Mouse	MGI:MGI:5532914|PMID:20696765
Molecular Function	GO:0017154	semaphorin receptor activity	PLXNB3	IDA		Human	PMID:15218527
Cellular Component	GO:0009986	cell surface	PLXNB3	IDA		Human	PMID:16122393
Biological Process	GO:0060326	cell chemotaxis	PLXNB3	IDA		Human	PMID:15218527
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	PLXNB3	IDA		Human	PMID:16122393
Biological Process	GO:0007162	negative regulation of cell adhesion	PLXNB3	IDA		Human	PMID:15218527
Biological Process	GO:0030336	negative regulation of cell migration	PLXNB3	IMP		Human	PMID:20696765
Biological Process	GO:0030336	negative regulation of cell migration	Plxnb3	IMP		Rat	PMID:20696765|RGD:8554409
Biological Process	GO:0034260	negative regulation of GTPase activity	PLXNB3	IMP		Human	PMID:20696765
Biological Process	GO:0010593	negative regulation of lamellipodium assembly	Plxnb3	IMP		Rat	PMID:20696765|RGD:8554409
Biological Process	GO:0050918	positive chemotaxis	PLXNB3	IDA		Human	PMID:15218527
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	PLXNB3	IMP		Human	PMID:19850054
Biological Process	GO:0010976	positive regulation of neuron projection development	PLXNB3	IDA		Human	PMID:16122393
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	PLXNB3	IDA		Human	PMID:15218527
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxnb3	IMP		Rat	PMID:20696765|RGD:8554409

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern