Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLXND1
  • Mouse genes Plxnd1
  • Rat genes Plxnd1
  • Zfish genes plxnd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plxnd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PLXND1	IPI	UniProtKB:O15041	Human	PMID:17318185
Molecular Function	GO:0005515	protein binding	PLXND1	IPI	UniProtKB:Q9H3S1	Human	PMID:17318185
Molecular Function	GO:0005515	protein binding	PLXND1	IPI	UniProtKB:P22736	Human	PMID:24139859
Molecular Function	GO:0005515	protein binding	PLXND1	IPI	UniProtKB:P70275	Human	PMID:24139859
Molecular Function	GO:0005515	protein binding	PLXND1	IPI	UniProtKB:P70275	Human	PMID:24841563
Molecular Function	GO:0005515	protein binding	PLXND1	IPI	UniProtKB:P09067	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Plxnd1	IPI	UniProtKB:O15041	Mouse	MGI:MGI:5646051|PMID:25985275
Molecular Function	GO:0005515	protein binding	Plxnd1	IPI	PR:P97333	Mouse	PMID:15239958
Molecular Function	GO:0019904	protein domain specific binding	PLXND1	IPI	UniProtKB:Q9Y3L3	Human	PMID:24841563
Molecular Function	GO:0017154	semaphorin receptor activity	Plxnd1	IMP		Mouse	MGI:MGI:5646051|PMID:25985275
Molecular Function	GO:0017154	semaphorin receptor activity	Plxnd1	IDA		Mouse	MGI:MGI:3703310|PMID:17318185
Molecular Function	GO:0017154	semaphorin receptor activity	Plxnd1	IPI	PR:P97333	Mouse	PMID:15239958
Cellular Component	GO:0030424	axon	Plxnd1	IDA		Mouse	MGI:MGI:5646051|PMID:25985275
Cellular Component	GO:0044297	cell body	Plxnd1	IDA		Mouse	MGI:MGI:5646051|PMID:25985275
Cellular Component	GO:0098978	glutamatergic synapse	Plxnd1	IMP		Mouse	PMID:22179111
Cellular Component	GO:0098978	glutamatergic synapse	Plxnd1	IDA		Mouse	PMID:22179111
Cellular Component	GO:0030027	lamellipodium	PLXND1	IDA		Human	PMID:24841563
Cellular Component	GO:0005886	plasma membrane	Plxnd1	IDA		Mouse	MGI:MGI:3703310|PMID:17318185
Biological Process	GO:0035476	angioblast cell migration	plxnd1	IMP	ZFIN:ZDB-GENO-010621-2	Zfish	PMID:11861480
Biological Process	GO:0035476	angioblast cell migration	plxnd1	IMP	ZFIN:ZDB-GENO-010621-1	Zfish	PMID:11861480
Biological Process	GO:0001525	angiogenesis	Plxnd1	IMP		Mouse	MGI:MGI:3828912|PMID:18992737
Biological Process	GO:0035904	aorta development	Plxnd1	IMP		Mouse	PMID:25807483
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	Plxnd1	IMP	MGI:MGI:5544786	Mouse	PMID:23918385
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	Plxnd1	IMP	MGI:MGI:3050678	Mouse	PMID:15239958
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	plxnd1	IMP		Zfish	PMID:15239959
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	plxnd1	IMP	ZFIN:ZDB-GENO-010621-1	Zfish	PMID:11861480
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	plxnd1	IMP	ZFIN:ZDB-GENO-010621-2	Zfish	PMID:11861480
Biological Process	GO:0003279	cardiac septum development	Plxnd1	IMP		Mouse	PMID:25807483
Biological Process	GO:0060976	coronary vasculature development	Plxnd1	IMP		Mouse	PMID:25807483
Biological Process	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	Plxnd1	IDA		Mouse	PMID:17626059
Biological Process	GO:0048048	embryonic eye morphogenesis	plxnd1	IMP	ZFIN:ZDB-GENO-010621-3	Zfish	PMID:17937808
Biological Process	GO:0043542	endothelial cell migration	Plxnd1	IMP		Mouse	MGI:MGI:3828912|PMID:18992737
Biological Process	GO:0001822	kidney development	Plxnd1	IMP	MGI:MGI:5316780	Mouse	PMID:27002738
Biological Process	GO:0001822	kidney development	Plxnd1	IMP	MGI:MGI:5476170	Mouse	PMID:27002738
Biological Process	GO:0001822	kidney development	Plxnd1	IMP	MGI:MGI:5648017	Mouse	PMID:27002738
Biological Process	GO:0001763	morphogenesis of a branching structure	plxnd1	IMP		Zfish	PMID:15239959
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Plxnd1	IMP		Mouse	MGI:MGI:5646051|PMID:25985275
Biological Process	GO:0003151	outflow tract morphogenesis	Plxnd1	IMP	MGI:MGI:5544786	Mouse	PMID:23918385
Biological Process	GO:0032092	positive regulation of protein binding	Plxnd1	IDA		Mouse	PMID:15239958
Biological Process	GO:0045765	regulation of angiogenesis	Plxnd1	IMP		Mouse	MGI:MGI:3703310|PMID:17318185
Biological Process	GO:0030334	regulation of cell migration	Plxnd1	IMP		Mouse	MGI:MGI:3703310|PMID:17318185
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxnd1	IGI	UniProtKB:O15041	Mouse	MGI:MGI:5646051|PMID:25985275
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxnd1	IMP		Mouse	MGI:MGI:3703310|PMID:17318185
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxnd1	IMP		Mouse	MGI:MGI:5693177|PMID:26053665
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxnd1	IGI	MGI:MGI:106206	Mouse	PMID:15239958
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxnd1	IGI	MGI:MGI:1100492	Mouse	PMID:15239958
Biological Process	GO:0002040	sprouting angiogenesis	plxnd1	IMP	ZFIN:ZDB-GENO-120717-5	Zfish	PMID:31050647
Biological Process	GO:0002040	sprouting angiogenesis	plxnd1	IGI	ZFIN:ZDB-GENE-060726-1,ZFIN:ZDB-GENE-040426-921	Zfish	PMID:31050647
Biological Process	GO:0002040	sprouting angiogenesis	plxnd1	IMP	ZFIN:ZDB-GENO-010621-2	Zfish	PMID:11861480
Biological Process	GO:0002040	sprouting angiogenesis	plxnd1	IGI	ZFIN:ZDB-GENO-121130-2,ZFIN:ZDB-MRPHLNO-050906-5	Zfish	PMID:21802375
Biological Process	GO:0002040	sprouting angiogenesis	plxnd1	IMP	ZFIN:ZDB-GENO-100510-19	Zfish	PMID:21802375
Biological Process	GO:0002040	sprouting angiogenesis	plxnd1	IGI	ZFIN:ZDB-GENO-100510-19,ZFIN:ZDB-MRPHLNO-100510-4	Zfish	PMID:19422817
Biological Process	GO:0002040	sprouting angiogenesis	plxnd1	IGI	ZFIN:ZDB-GENO-121130-2,ZFIN:ZDB-MRPHLNO-110921-6	Zfish	PMID:21802375
Biological Process	GO:0002040	sprouting angiogenesis	plxnd1	IMP	ZFIN:ZDB-GENO-010621-1	Zfish	PMID:11861480
Biological Process	GO:0007416	synapse assembly	Plxnd1	IMP		Mouse	MGI:MGI:5311980|PMID:22179111
Biological Process	GO:0008039	synaptic target recognition	Plxnd1	IMP		Mouse	PMID:22179111
Biological Process	GO:0008039	synaptic target recognition	Plxnd1	IDA		Mouse	PMID:22179111

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern