Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PMCH,PMCHL1,PMCHL2
  • Mouse genes Pmch
  • Rat genes Pmch
  • Zfish genes pmch,pmchl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pmch

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031777	type 1 melanin-concentrating hormone receptor binding	Pmch	IDA		Rat	PMID:10421367|RGD:1642494
Cellular Component	GO:0005615	extracellular space	Pmch	IDA		Rat	PMID:11483240|RGD:1642488
Cellular Component	GO:0005634	nucleus	Pmch	IDA		Mouse	PMID:8724342
Biological Process	GO:0042756	drinking behavior	Pmch	IDA		Rat	PMID:17188345|RGD:1642491
Biological Process	GO:0007631	feeding behavior	Pmch	IMP		Mouse	MGI:MGI:2450007|PMID:11867747
Biological Process	GO:0007631	feeding behavior	Pmch	IDA		Rat	PMID:12355323|RGD:1642487
Biological Process	GO:0042593	glucose homeostasis	Pmch	IDA		Rat	PMID:16002548|RGD:1642484
Biological Process	GO:0007595	lactation	Pmch	IEP		Rat	PMID:14962080|RGD:1642485
Biological Process	GO:0045776	negative regulation of blood pressure	Pmch	IDA		Rat	PMID:17045349|RGD:1642492
Biological Process	GO:0032227	negative regulation of synaptic transmission, dopaminergic	Pmch	IDA		Rat	PMID:15555641|RGD:1642493
Biological Process	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep	Pmch	IDA		Rat	PMID:12964948|RGD:1642489
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Pmch	IDA		Rat	PMID:10559938|RGD:1624363
Biological Process	GO:0002027	regulation of heart rate	Pmch	IDA		Rat	PMID:17045349|RGD:1642492
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	Pmch	IMP		Rat	PMID:11814630|RGD:729531
Biological Process	GO:0009409	response to cold	Pmch	IMP		Rat	PMID:12960043|RGD:1642490

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern