Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PMS2,PMS2P1,PMS2P2,PMS2P6
  • Mouse genes Pms2
  • Rat genes Pms2
  • Zfish genes pms2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pms2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	PMS2	IDA		Human	PMID:10871409
Molecular Function	GO:0032407	MutSalpha complex binding	PMS2	IDA		Human	PMID:16403449
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:11292842
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:11793469
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:12810663
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:16083711
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:17581638
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:20533529
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:Q9Y2M0	Human	PMID:20603073
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:20706999
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:22252508
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:25077178
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PMS2	IPI	UniProtKB:P40692	Human	PMID:34591612
Molecular Function	GO:0032138	single base insertion or deletion binding	PMS2	IDA		Human	PMID:10871409
Molecular Function	GO:0003697	single-stranded DNA binding	PMS2	IDA		Human	PMID:11809883
Cellular Component	GO:0005829	cytosol	PMS2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032389	MutLalpha complex	Pms2	IDA		Mouse	PMID:16713580
Cellular Component	GO:0005654	nucleoplasm	PMS2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PMS2	IDA		Human	PMID:23709753
Biological Process	GO:0006974	DNA damage response	Pms2	IMP	MGI:MGI:1857947	Mouse	PMID:16204034
Biological Process	GO:0006974	DNA damage response	Pms2	IGI	MGI:MGI:1353455	Mouse	PMID:16204034
Biological Process	GO:0006281	DNA repair	Pms2	IMP	MGI:MGI:1857947	Mouse	PMID:15480418
Biological Process	GO:0006298	mismatch repair	PMS2	IDA		Human	PMID:10871409
Biological Process	GO:0006298	mismatch repair	PMS2	IDA		Human	PMID:23709753
Biological Process	GO:0006298	mismatch repair	PMS2	IMP		Human	PMID:9618520
Biological Process	GO:0006298	mismatch repair	Pms2	IGI	MGI:MGI:1353455	Mouse	PMID:16204034
Biological Process	GO:0006298	mismatch repair	Pms2	IMP	MGI:MGI:1857946	Mouse	PMID:11313994
Biological Process	GO:0006298	mismatch repair	Pms2	IMP	MGI:MGI:1857947	Mouse	PMID:16204034
Biological Process	GO:0006298	mismatch repair	Pms2	IMP	MGI:MGI:1857947	Mouse	PMID:16728433
Biological Process	GO:0006298	mismatch repair	Pms2	IMP	MGI:MGI:1857947	Mouse	PMID:10359802
Biological Process	GO:0006298	mismatch repair	Pms2	IMP	MGI:MGI:1857947	Mouse	PMID:10429667
Biological Process	GO:0006298	mismatch repair	Pms2	IMP	MGI:MGI:1857947	Mouse	PMID:9500552
Biological Process	GO:0006298	mismatch repair	Pms2	IMP	MGI:MGI:1857947	Mouse	PMID:23071719
Biological Process	GO:0048298	positive regulation of isotype switching to IgA isotypes	Pms2	IGI	UniProtKB:Q9JK91	Mouse	MGI:MGI:1342394|PMID:10430621
Biological Process	GO:0048298	positive regulation of isotype switching to IgA isotypes	Pms2	IMP		Mouse	MGI:MGI:1342394|PMID:10430621
Biological Process	GO:0048304	positive regulation of isotype switching to IgG isotypes	Pms2	IMP		Mouse	MGI:MGI:1342394|PMID:10430621
Biological Process	GO:0048304	positive regulation of isotype switching to IgG isotypes	Pms2	IGI	UniProtKB:Q9JK91	Mouse	MGI:MGI:1342394|PMID:10430621
Biological Process	GO:0009410	response to xenobiotic stimulus	Pms2	IEP		Rat	PMID:11056294|RGD:727220
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	Pms2	IMP		Mouse	MGI:MGI:1261707|PMID:9618520
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	Pms2	IMP	MGI:MGI:1857947	Mouse	PMID:10429667
Biological Process	GO:0016447	somatic recombination of immunoglobulin gene segments	Pms2	IMP	MGI:MGI:1857947	Mouse	PMID:11828012

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern