Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PNMT
  • Mouse genes Pnmt
  • Rat genes Pnmt
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pnmt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004603	phenylethanolamine N-methyltransferase activity	PNMT	IMP		Human	PMID:16277617
Molecular Function	GO:0004603	phenylethanolamine N-methyltransferase activity	PNMT	IMP		Human	PMID:20496117
Molecular Function	GO:0004603	phenylethanolamine N-methyltransferase activity	PNMT	IDA		Human	PMID:8812853
Molecular Function	GO:0004603	phenylethanolamine N-methyltransferase activity	Pnmt	IDA		Mouse	MGI:MGI:3810618|PMID:17698731
Molecular Function	GO:0004603	phenylethanolamine N-methyltransferase activity	Pnmt	IDA		Rat	PMID:13863458|RGD:151665728
Molecular Function	GO:0004603	phenylethanolamine N-methyltransferase activity	Pnmt	IDA		Rat	PMID:683413|RGD:151665731
Molecular Function	GO:0004603	phenylethanolamine N-methyltransferase activity	Pnmt	IDA		Rat	PMID:7503429|RGD:4139901
Molecular Function	GO:0004603	phenylethanolamine N-methyltransferase activity	Pnmt	IDA		Rat	PMID:7914070|RGD:4139902
Molecular Function	GO:0005515	protein binding	PNMT	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PNMT	IPI	UniProtKB:Q9P2G9-2	Human	PMID:32296183
Cellular Component	GO:0030424	axon	Pnmt	IDA		Rat	PMID:19651110|RGD:5129482
Cellular Component	GO:0005737	cytoplasm	Pnmt	IDA		Rat	PMID:20478367|RGD:5129236
Cellular Component	GO:0030425	dendrite	Pnmt	IDA		Rat	PMID:20434498|RGD:5129701
Cellular Component	GO:0043025	neuronal cell body	Pnmt	IDA		Rat	PMID:15869485|RGD:5130742
Cellular Component	GO:0043204	perikaryon	Pnmt	IDA		Rat	PMID:20434498|RGD:5129701
Cellular Component	GO:0043195	terminal bouton	Pnmt	IDA		Rat	PMID:19651110|RGD:5129482
Cellular Component	GO:0043196	varicosity	Pnmt	IDA		Rat	PMID:19651110|RGD:5129482
Biological Process	GO:0030325	adrenal gland development	Pnmt	IEP		Rat	PMID:16140489|RGD:5130728
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Pnmt	IEP		Rat	PMID:15564339|RGD:5130762
Biological Process	GO:0071363	cellular response to growth factor stimulus	Pnmt	IEP		Rat	PMID:16926281|RGD:5130702
Biological Process	GO:0071375	cellular response to peptide hormone stimulus	Pnmt	IEP		Rat	PMID:16926281|RGD:5130702
Biological Process	GO:0042418	epinephrine biosynthetic process	Pnmt	IDA		Rat	PMID:7914070|RGD:4139902
Biological Process	GO:0042415	norepinephrine metabolic process	Pnmt	IDA		Rat	PMID:3945626|RGD:5130757
Biological Process	GO:0014823	response to activity	Pnmt	IEP		Rat	PMID:19120122|RGD:2303957
Biological Process	GO:0009409	response to cold	Pnmt	IEP		Rat	PMID:17356229|RGD:5130210
Biological Process	GO:0031960	response to corticosteroid	Pnmt	IEP		Rat	PMID:16965914|RGD:5130656
Biological Process	GO:0045471	response to ethanol	Pnmt	IEP		Rat	PMID:21382450|RGD:5129695
Biological Process	GO:0045472	response to ether	Pnmt	IEP		Rat	PMID:19120141|RGD:5129521
Biological Process	GO:0001666	response to hypoxia	Pnmt	IEP		Rat	PMID:21046459|RGD:5129698
Biological Process	GO:0035902	response to immobilization stress	Pnmt	IEP		Rat	PMID:17683801|RGD:9684985
Biological Process	GO:0032868	response to insulin	Pnmt	IEP		Rat	PMID:15677399|RGD:5130754
Biological Process	GO:0035900	response to isolation stress	Pnmt	IEP		Rat	PMID:20203532|RGD:9684987
Biological Process	GO:0043434	response to peptide hormone	Pnmt	IEP		Rat	PMID:15380299|RGD:5130764
Biological Process	GO:0009414	response to water deprivation	Pnmt	IEP		Rat	PMID:15637337|RGD:5130758
Biological Process	GO:0050909	sensory perception of taste	Pnmt	IEP		Rat	PMID:20478367|RGD:5129236
Biological Process	GO:0035176	social behavior	Pnmt	IEP		Rat	PMID:15345906|RGD:5130765

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern