Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PNPT1
  • Mouse genes Pnpt1
  • Rat genes Pnpt1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pnpt1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	PNPT1	IDA		Human	PMID:19509288
Molecular Function	GO:0042802	identical protein binding	PNPT1	IPI	UniProtKB:Q8TCS8	Human	PMID:19509288
Molecular Function	GO:0035198	miRNA binding	PNPT1	IDA		Human	PMID:20547861
Molecular Function	GO:0034046	poly(G) binding	PNPT1	IDA		Human	PMID:18083836
Molecular Function	GO:0008266	poly(U) RNA binding	PNPT1	IDA		Human	PMID:18083836
Molecular Function	GO:0004654	polyribonucleotide nucleotidyltransferase activity	PNPT1	IDA		Human	PMID:18083836
Molecular Function	GO:0004654	polyribonucleotide nucleotidyltransferase activity	Pnpt1	IDA		Rat	PMID:7295810|RGD:11554177
Molecular Function	GO:0005515	protein binding	PNPT1	IPI	UniProtKB:P56279	Human	PMID:16934922
Molecular Function	GO:0005515	protein binding	PNPT1	IPI	UniProtKB:Q8IYB8	Human	PMID:19509288
Molecular Function	GO:0005515	protein binding	PNPT1	IPI	UniProtKB:Q8IYB8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PNPT1	IPI	UniProtKB:Q12849	Human	PMID:29967381
Molecular Function	GO:0005515	protein binding	PNPT1	IPI	UniProtKB:P78563-4	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	PNPT1	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	PNPT1	IDA		Human	PMID:16055741
Cellular Component	GO:0005829	cytosol	PNPT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Pnpt1	IDA		Rat	PMID:191106|RGD:11554175
Cellular Component	GO:0045025	mitochondrial degradosome	PNPT1	IDA		Human	PMID:19509288
Cellular Component	GO:0045025	mitochondrial degradosome	PNPT1	IDA		Human	PMID:29967381
Cellular Component	GO:0005758	mitochondrial intermembrane space	PNPT1	IDA		Human	PMID:16966381
Cellular Component	GO:0005758	mitochondrial intermembrane space	Pnpt1	IDA		Mouse	PMID:16966381
Cellular Component	GO:0005739	mitochondrion	PNPT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	PNPT1	IDA		Human	PMID:16055741
Cellular Component	GO:0005739	mitochondrion	PNPT1	IDA		Human	PMID:19864255
Cellular Component	GO:0005739	mitochondrion	PNPT1	IDA		Human	PMID:20691904
Cellular Component	GO:0005739	mitochondrion	Pnpt1	IDA		Mouse	MGI:MGI:3689653|PMID:16966381
Cellular Component	GO:0005739	mitochondrion	Pnpt1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005634	nucleus	Pnpt1	IDA		Rat	PMID:7295810|RGD:11554177
Cellular Component	GO:0042788	polysomal ribosome	Pnpt1	IDA		Rat	PMID:191106|RGD:11554175
Biological Process	GO:0035458	cellular response to interferon-beta	PNPT1	IDA		Human	PMID:16410805
Biological Process	GO:0034599	cellular response to oxidative stress	PNPT1	IDA		Human	PMID:18501193
Biological Process	GO:0097421	liver regeneration	Pnpt1	IEP		Rat	PMID:191106|RGD:11554175
Biological Process	GO:0000958	mitochondrial mRNA catabolic process	PNPT1	IDA		Human	PMID:20691904
Biological Process	GO:0000958	mitochondrial mRNA catabolic process	Pnpt1	IMP		Mouse	MGI:MGI:4881376|PMID:20691904
Biological Process	GO:0097222	mitochondrial mRNA polyadenylation	PNPT1	IMP		Human	PMID:18083837
Biological Process	GO:0000965	mitochondrial RNA 3'-end processing	PNPT1	IMP		Human	PMID:18083837
Biological Process	GO:0000964	mitochondrial RNA 5'-end processing	PNPT1	IMP		Human	PMID:18083837
Biological Process	GO:0000957	mitochondrial RNA catabolic process	PNPT1	IDA		Human	PMID:18501193
Biological Process	GO:0070584	mitochondrion morphogenesis	Pnpt1	IMP		Mouse	MGI:MGI:3689653|PMID:16966381
Biological Process	GO:0070584	mitochondrion morphogenesis	Pnpt1	IMP		Mouse	MGI:MGI:4881376|PMID:20691904
Biological Process	GO:0006402	mRNA catabolic process	PNPT1	IDA		Human	PMID:12721301
Biological Process	GO:0006402	mRNA catabolic process	PNPT1	IDA		Human	PMID:16055741
Biological Process	GO:0045926	negative regulation of growth	PNPT1	IDA		Human	PMID:12721301
Biological Process	GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	PNPT1	IDA		Human	PMID:16934922
Biological Process	GO:2000627	positive regulation of miRNA catabolic process	PNPT1	IDA		Human	PMID:20547861
Biological Process	GO:0000962	positive regulation of mitochondrial RNA catabolic process	PNPT1	IDA		Human	PMID:19509288
Biological Process	GO:0000962	positive regulation of mitochondrial RNA catabolic process	PNPT1	IDA		Human	PMID:29967381
Biological Process	GO:0061014	positive regulation of mRNA catabolic process	PNPT1	IMP		Human	PMID:16410805
Biological Process	GO:0061014	positive regulation of mRNA catabolic process	Pnpt1	IDA		Rat	PMID:737213|RGD:11554176
Biological Process	GO:0051260	protein homooligomerization	PNPT1	IDA		Human	PMID:20691904
Biological Process	GO:0070207	protein homotrimerization	PNPT1	IDA		Human	PMID:19509288
Biological Process	GO:0070207	protein homotrimerization	PNPT1	IDA		Human	PMID:20691904
Biological Process	GO:0051726	regulation of cell cycle	PNPT1	IDA		Human	PMID:12721301
Biological Process	GO:0043457	regulation of cellular respiration	Pnpt1	IMP		Mouse	MGI:MGI:4881376|PMID:20691904
Biological Process	GO:0043457	regulation of cellular respiration	Pnpt1	IMP		Mouse	MGI:MGI:3689653|PMID:16966381
Biological Process	GO:2000772	regulation of cellular senescence	PNPT1	IDA		Human	PMID:16055741
Biological Process	GO:0051591	response to cAMP	Pnpt1	IEP		Rat	PMID:189502|RGD:11554171
Biological Process	GO:0060416	response to growth hormone	Pnpt1	IEP		Rat	PMID:7470604|RGD:11554172
Biological Process	GO:0006401	RNA catabolic process	PNPT1	IDA		Human	PMID:18083836
Biological Process	GO:0035927	RNA import into mitochondrion	PNPT1	IDA		Human	PMID:20691904
Biological Process	GO:0043631	RNA polyadenylation	PNPT1	IDA		Human	PMID:18083836
Biological Process	GO:0035928	rRNA import into mitochondrion	PNPT1	IDA		Human	PMID:20691904

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern