Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PODXL
  • Mouse genes Podxl
  • Rat genes Podxl
  • Zfish genes podxl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Podxl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PODXL	IPI	UniProtKB:P46940	Human	PMID:22662192
Molecular Function	GO:0005515	protein binding	Podxl	IPI	RGD:620380	Rat	PMID:11457882|RGD:634171
Molecular Function	GO:0005515	protein binding	Podxl	IPI	UniProtKB:P31977	Rat	PMID:11457882|RGD:634171
Molecular Function	GO:0005515	protein binding	Podxl	IPI	UniProtKB:Q920G2	Rat	PMID:11457882|RGD:634171
Molecular Function	GO:0005515	protein binding	Podxl	IPI	UniProtKB:Q9JJ19	Rat	PMID:11457882|RGD:634171
Molecular Function	GO:0005515	protein binding	Podxl	IPI	RGD:621161	Rat	PMID:11461930|RGD:7207839
Cellular Component	GO:0016324	apical plasma membrane	Podxl	IDA		Mouse	MGI:MGI:4456941|PMID:17311105
Cellular Component	GO:0016324	apical plasma membrane	Podxl	IDA		Rat	PMID:11457882|RGD:634171
Cellular Component	GO:0016324	apical plasma membrane	Podxl	IDA		Rat	PMID:11461930|RGD:7207839
Cellular Component	GO:0044297	cell body	Podxl	IDA		Rat	PMID:11461930|RGD:7207839
Cellular Component	GO:0034451	centriolar satellite	PODXL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	PODXL	IDA		Human	PMID:18456258
Cellular Component	GO:0070062	extracellular exosome	PODXL	IDA		Human	PMID:15326289
Cellular Component	GO:0070062	extracellular exosome	PODXL	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PODXL	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	PODXL	HDA		Human	PMID:16502470
Cellular Component	GO:0030175	filopodium	PODXL	IDA		Human	PMID:18456258
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PODXL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030027	lamellipodium	PODXL	IDA		Human	PMID:18456258
Cellular Component	GO:0031528	microvillus membrane	Podxl	IDA		Mouse	MGI:MGI:4456941|PMID:17311105
Cellular Component	GO:0005730	nucleolus	PODXL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PODXL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PODXL	IDA		Human	PMID:18456258
Cellular Component	GO:0005886	plasma membrane	Podxl	IDA		Mouse	PMID:10591182
Cellular Component	GO:0001726	ruffle	PODXL	IDA		Human	PMID:18456258
Cellular Component	GO:0036057	slit diaphragm	Podxl	IDA		Rat	PMID:15994232|RGD:8553727
Biological Process	GO:0016477	cell migration	Podxl	IMP		Mouse	MGI:MGI:5285160|PMID:20395446
Biological Process	GO:0050900	leukocyte migration	Podxl	IMP	MGI:MGI:1351317	Mouse	PMID:15701716
Biological Process	GO:0007162	negative regulation of cell adhesion	Podxl	IDA		Rat	PMID:10982412|RGD:633592
Biological Process	GO:0022408	negative regulation of cell-cell adhesion	Podxl	IMP		Mouse	MGI:MGI:5285160|PMID:20395446
Biological Process	GO:0072015	podocyte development	Podxl	IEP		Rat	PMID:15994232|RGD:8553727
Biological Process	GO:0030335	positive regulation of cell migration	PODXL	IDA		Human	PMID:18456258
Biological Process	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	PODXL	IDA		Human	PMID:18456258
Biological Process	GO:0035775	pronephric glomerulus morphogenesis	podxl	IMP	ZFIN:ZDB-MRPHLNO-141024-1	Zfish	PMID:24224085
Biological Process	GO:0032534	regulation of microvillus assembly	Podxl	IDA		Mouse	MGI:MGI:4456941|PMID:17311105

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern