Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POLK
  • Mouse genes Polk
  • Rat genes Polk
  • Zfish genes polk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Polk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0060090	molecular adaptor activity	Polk	EXP		Mouse	MGI:MGI:6836895|PMID:22700975
Molecular Function	GO:0005515	protein binding	Polk	IPI	PR:P23611	Mouse	PMID:25331958
Cellular Component	GO:0016604	nuclear body	POLK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	POLK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	POLK	IDA		Human	PMID:12414988
Cellular Component	GO:0005634	nucleus	Polk	IDA		Mouse	PMID:12555660
Cellular Component	GO:0090734	site of DNA damage	POLK	IDA		Human	PMID:28297716
Biological Process	GO:0034644	cellular response to UV	POLK	IDA		Human	PMID:28297716
Biological Process	GO:0006974	DNA damage response	POLK	IDA		Human	PMID:28297716
Biological Process	GO:0006281	DNA repair	POLK	IDA		Human	PMID:28297716
Biological Process	GO:0006281	DNA repair	Polk	IMP	MGI:MGI:2445458	Mouse	PMID:12555660
Biological Process	GO:0042276	error-prone translesion synthesis	POLK	IDA		Human	PMID:28297716
Biological Process	GO:0006297	nucleotide-excision repair, DNA gap filling	POLK	IMP		Human	PMID:20227374

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern