Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POLN
  • Mouse genes Poln
  • Rat genes Poln
  • Zfish genes poln
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Poln

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030332	cyclin binding	POLN	IPI	UniProtKB:P12004	Human	PMID:19995904
Molecular Function	GO:0034061	DNA polymerase activity	poln	IDA		Zfish	PMID:26269593
Molecular Function	GO:0003887	DNA-directed DNA polymerase activity	POLN	IDA		Human	PMID:12794064
Molecular Function	GO:0003887	DNA-directed DNA polymerase activity	POLN	IDA		Human	PMID:17118716
Molecular Function	GO:0003887	DNA-directed DNA polymerase activity	POLN	IDA		Human	PMID:19908865
Molecular Function	GO:0005515	protein binding	POLN	IPI	UniProtKB:Q06609	Human	PMID:19995904
Molecular Function	GO:0005515	protein binding	POLN	IPI	UniProtKB:Q9BXW9	Human	PMID:19995904
Molecular Function	GO:0005515	protein binding	POLN	IPI	UniProtKB:Q9NVI1	Human	PMID:19995904
Cellular Component	GO:0005654	nucleoplasm	POLN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	POLN	IDA		Human	PMID:12794064
Biological Process	GO:0022616	DNA strand elongation	poln	IDA		Zfish	PMID:26269593
Biological Process	GO:0000724	double-strand break repair via homologous recombination	POLN	IMP		Human	PMID:19995904
Biological Process	GO:0070987	error-free translesion synthesis	poln	IDA		Zfish	PMID:26269593
Biological Process	GO:0036297	interstrand cross-link repair	POLN	IMP		Human	PMID:19908865
Biological Process	GO:0036297	interstrand cross-link repair	POLN	IMP		Human	PMID:19995904
Biological Process	GO:0019985	translesion synthesis	POLN	IMP		Human	PMID:19908865
Biological Process	GO:0019985	translesion synthesis	POLN	IDA		Human	PMID:20102227
Biological Process	GO:0019985	translesion synthesis	poln	IDA		Zfish	PMID:26269593

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern