Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PORCN
  • Mouse genes Porcn
  • Rat genes Porcn
  • Zfish genes porcn,porcnl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Porcn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990698	palmitoleoyltransferase activity	Porcn	IDA		Mouse	MGI:MGI:5607507|PMID:24798332
Molecular Function	GO:0005515	protein binding	Porcn	IPI	PR:P22724	Mouse	PMID:10866835
Molecular Function	GO:0005515	protein binding	Porcn	IPI	PR:P22726	Mouse	PMID:10866835
Molecular Function	GO:0005515	protein binding	Porcn	IPI	PR:P24383	Mouse	PMID:10866835
Molecular Function	GO:0005515	protein binding	Porcn	IPI	PR:P27467	Mouse	PMID:10866835
Molecular Function	GO:0005515	protein binding	Porcn	IPI	PR:P04426	Mouse	PMID:10866835
Molecular Function	GO:0005515	protein binding	Porcn	IPI	PR:P22725	Mouse	PMID:10866835
Molecular Function	GO:0005515	protein binding	Porcn	IPI	PR:P22727	Mouse	PMID:10866835
Molecular Function	GO:0005515	protein binding	Porcn	IPI	PR:P28047	Mouse	PMID:10866835
Molecular Function	GO:0005515	protein binding	Porcn	IPI	PR:P17553	Mouse	PMID:10866835
Molecular Function	GO:0017147	Wnt-protein binding	Porcn	IPI	UniProtKB:P27467	Mouse	MGI:MGI:5607507|PMID:24798332
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Porcn	IDA		Mouse	PMID:22632720
Cellular Component	GO:0005783	endoplasmic reticulum	Porcn	IDA		Mouse	MGI:MGI:5607507|PMID:24798332
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Porcn	IDA		Mouse	PMID:10866835
Cellular Component	GO:0098978	glutamatergic synapse	Porcn	IDA		Mouse	PMID:26776514
Cellular Component	GO:0098978	glutamatergic synapse	Porcn	IMP		Mouse	PMID:26776514
Cellular Component	GO:0098978	glutamatergic synapse	Porcn	IEP		Mouse	PMID:26776514
Biological Process	GO:0060027	convergent extension involved in gastrulation	porcn	IMP	ZFIN:ZDB-MRPHLNO-120614-3	Zfish	PMID:22357957
Biological Process	GO:0060027	convergent extension involved in gastrulation	porcn	IMP	ZFIN:ZDB-MRPHLNO-120614-4,ZFIN:ZDB-MRPHLNO-120615-1	Zfish	PMID:22357957
Biological Process	GO:0060027	convergent extension involved in gastrulation	porcn	IGI	ZFIN:ZDB-MRPHLNO-041217-10,ZFIN:ZDB-MRPHLNO-120614-3	Zfish	PMID:22357957
Biological Process	GO:0060027	convergent extension involved in gastrulation	porcn	IMP	ZFIN:ZDB-MRPHLNO-120614-3,ZFIN:ZDB-MRPHLNO-120614-4	Zfish	PMID:22357957
Biological Process	GO:0060027	convergent extension involved in gastrulation	porcn	IGI	ZFIN:ZDB-MRPHLNO-041217-11,ZFIN:ZDB-MRPHLNO-120614-3	Zfish	PMID:22357957
Biological Process	GO:0009100	glycoprotein metabolic process	Porcn	IDA		Mouse	PMID:10866835
Biological Process	GO:0006497	protein lipidation	Porcn	IDA		Mouse	MGI:MGI:5621264|PMID:17141155
Biological Process	GO:0006497	protein lipidation	Porcn	IDA		Mouse	MGI:MGI:5607507|PMID:24798332
Biological Process	GO:0006497	protein lipidation	porcn	IMP	ZFIN:ZDB-MRPHLNO-120614-3	Zfish	PMID:22357957
Biological Process	GO:0045234	protein palmitoleylation	Porcn	IMP		Mouse	MGI:MGI:5621264|PMID:17141155
Biological Process	GO:0045234	protein palmitoleylation	Porcn	IDA		Mouse	MGI:MGI:5607507|PMID:24798332
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Porcn	IEP		Mouse	PMID:26776514
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Porcn	IMP		Mouse	PMID:26776514
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Porcn	IDA		Mouse	PMID:26776514
Biological Process	GO:0061355	Wnt protein secretion	porcn	IMP	ZFIN:ZDB-MRPHLNO-120614-3	Zfish	PMID:22357957
Biological Process	GO:0016055	Wnt signaling pathway	Porcn	IMP		Mouse	MGI:MGI:5621264|PMID:17141155
Biological Process	GO:0016055	Wnt signaling pathway	Porcn	IDA		Mouse	MGI:MGI:5607507|PMID:24798332

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern