Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POSTN
  • Mouse genes Postn
  • Rat genes Postn
  • Zfish genes postna,postnb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Postn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008201	heparin binding	Postn	IDA		Mouse	MGI:MGI:3687423|PMID:7663166
Molecular Function	GO:0046872	metal ion binding	POSTN	IDA		Human	PMID:18450759
Molecular Function	GO:0005515	protein binding	POSTN	IPI	UniProtKB:Q15582	Human	PMID:19478074
Molecular Function	GO:0005515	protein binding	Postn	IPI	UniProtKB:Q15582	Rat	PMID:19478074|RGD:153298960
Cellular Component	GO:0062023	collagen-containing extracellular matrix	POSTN	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	POSTN	IDA		Human	PMID:18450759
Cellular Component	GO:0062023	collagen-containing extracellular matrix	POSTN	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	POSTN	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	POSTN	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	POSTN	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	POSTN	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Postn	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Postn	IDA		Mouse	MGI:MGI:3804342|PMID:18450759
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Postn	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005737	cytoplasm	Postn	IDA		Rat	PMID:19006175|RGD:10040956
Cellular Component	GO:0031012	extracellular matrix	Postn	IDA		Mouse	MGI:MGI:3690184|PMID:10404027
Cellular Component	GO:0031012	extracellular matrix	Postn	IDA		Mouse	PMID:24563484
Cellular Component	GO:0005615	extracellular space	Postn	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Postn	IDA		Rat	PMID:19006175|RGD:10040956
Cellular Component	GO:0005615	extracellular space	Postn	IDA		Rat	PMID:24523534|RGD:10041019
Cellular Component	GO:0031594	neuromuscular junction	Postn	IDA		Rat	PMID:19620321|RGD:10040958
Cellular Component	GO:0005802	trans-Golgi network	POSTN	IDA		Human	PMID:19478074
Biological Process	GO:1990523	bone regeneration	Postn	IEP		Rat	PMID:17878602|RGD:10041014
Biological Process	GO:0007155	cell adhesion	POSTN	IDA		Human	PMID:12235007
Biological Process	GO:0007155	cell adhesion	Postn	IDA		Mouse	MGI:MGI:3690184|PMID:10404027
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	Postn	IEP		Rat	PMID:16325820|RGD:10040989
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Postn	IEP		Rat	PMID:22886209|RGD:10040993
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Postn	IEP		Rat	PMID:20458732|RGD:10041020
Biological Process	GO:0071307	cellular response to vitamin K	POSTN	IDA		Human	PMID:18450759
Biological Process	GO:0071307	cellular response to vitamin K	Postn	IDA		Mouse	MGI:MGI:3804342|PMID:18450759
Biological Process	GO:0030198	extracellular matrix organization	Postn	IMP		Mouse	PMID:16314533
Biological Process	GO:0016203	muscle attachment	postnb	IMP		Zfish	PMID:15013807
Biological Process	GO:0001953	negative regulation of cell-matrix adhesion	Postn	IDA		Rat	PMID:15381649|RGD:10040999
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	Postn	IDA		Rat	PMID:15381649|RGD:10040999
Biological Process	GO:1990138	neuron projection extension	Postn	IMP		Rat	PMID:24523534|RGD:10041019
Biological Process	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	Postn	IMP		Rat	PMID:24260297|RGD:10041046
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	Postn	IMP		Rat	PMID:16325820|RGD:10040989
Biological Process	GO:0008593	regulation of Notch signaling pathway	Postn	IMP	MGI:MGI:3819350	Mouse	PMID:19723774
Biological Process	GO:0003073	regulation of systemic arterial blood pressure	Postn	IDA		Rat	PMID:15381649|RGD:10040999
Biological Process	GO:0032355	response to estradiol	Postn	IEP		Rat	PMID:18270434|RGD:10040955
Biological Process	GO:0001666	response to hypoxia	Postn	IEP		Rat	PMID:15121739|RGD:10041030
Biological Process	GO:0009612	response to mechanical stimulus	Postn	IEP		Rat	PMID:23453657|RGD:10040995
Biological Process	GO:0014850	response to muscle activity	Postn	IEP		Rat	PMID:19620321|RGD:10040958
Biological Process	GO:0009888	tissue development	Postn	IMP		Mouse	PMID:16314533
Biological Process	GO:0042060	wound healing	Postn	IEP		Rat	PMID:22681660|RGD:10040991

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern