Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POU1F1
  • Mouse genes Pou1f1
  • Rat genes Pou1f1
  • Zfish genes pou1f1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pou1f1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Pou1f1	IDA		Mouse	PMID:17392792
Molecular Function	GO:0003682	chromatin binding	Pou1f1	IDA		Mouse	PMID:17015435
Molecular Function	GO:0003682	chromatin binding	Pou1f1	IDA		Mouse	PMID:16678101
Molecular Function	GO:0003677	DNA binding	Pou1f1	IDA		Mouse	PMID:10367888
Molecular Function	GO:0003677	DNA binding	Pou1f1	IDA		Mouse	PMID:11891224
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pou1f1	IDA		Mouse	PMID:9305891
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pou1f1	IMP		Rat	PMID:19887646|RGD:8661635
Molecular Function	GO:0003700	DNA-binding transcription factor activity	POU1F1	IDA		Human	PMID:11301317
Molecular Function	GO:0003700	DNA-binding transcription factor activity	POU1F1	IDA		Human	PMID:9482665
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou1f1	IDA		Mouse	PMID:11891224
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	POU1F1	IDA		Human	PMID:26612202
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	POU1F1	IDA		Human	PMID:9685346
Molecular Function	GO:0106222	lncRNA binding	Pou1f1	IDA		Rat	PMID:30982661|RGD:151356638
Molecular Function	GO:0005515	protein binding	POU1F1	IPI	UniProtKB:P15289	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU1F1	IPI	UniProtKB:P35548	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU1F1	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU1F1	IPI	UniProtKB:Q03989	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU1F1	IPI	UniProtKB:Q14847-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU1F1	IPI	UniProtKB:Q3LI64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU1F1	IPI	UniProtKB:Q3LI76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU1F1	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU1F1	IPI	UniProtKB:Q969G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU1F1	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU1F1	IPI	UniProtKB:Q9Y4B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pou1f1	IPI	PR:O35627	Mouse	PMID:11891224
Molecular Function	GO:0005515	protein binding	Pou1f1	IPI	PR:O54915	Mouse	PMID:11891224
Molecular Function	GO:0005515	protein binding	Pou1f1	IPI	UniProtKB:Q07869	Mouse	PMID:11891224
Molecular Function	GO:0005515	protein binding	Pou1f1	IPI	PR:O09100	Mouse	PMID:10367888
Molecular Function	GO:0005515	protein binding	Pou1f1	IPI	UniProtKB:P11473	Mouse	PMID:11891224
Molecular Function	GO:0005515	protein binding	Pou1f1	IPI	UniProtKB:Q99697-3	Rat	PMID:12612071|RGD:10047309
Molecular Function	GO:0005515	protein binding	Pou1f1	IPI	UniProtKB:Q99697-3	Rat	PMID:9685346|RGD:10047377
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pou1f1	IMP		Rat	PMID:19887646|RGD:8661635
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	POU1F1	IPI	UniProtKB:Q99697-3	Human	PMID:12612071
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	POU1F1	IPI	UniProtKB:P19419	Human	PMID:26612202
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	POU1F1	IPI	UniProtKB:P78337	Human	PMID:26612202
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	POU1F1	IPI	UniProtKB:Q9UBR4	Human	PMID:26612202
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	POU1F1	IPI	UniProtKB:Q99697	Human	PMID:9685346
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou1f1	IDA		Mouse	PMID:7902581
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	POU1F1	IDA		Human	PMID:28473536
Cellular Component	GO:0000785	chromatin	Pou1f1	IMP		Rat	PMID:16030140|RGD:1601441
Cellular Component	GO:0005829	cytosol	POU1F1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	POU1F1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	POU1F1	IDA		Human	PMID:26612202
Cellular Component	GO:0005634	nucleus	Pou1f1	IDA		Mouse	PMID:12651892
Cellular Component	GO:0005634	nucleus	Pou1f1	IDA		Rat	PMID:16030140|RGD:1601441
Biological Process	GO:0021984	adenohypophysis development	Pou1f1	IMP		Rat	PMID:16216912|RGD:1601440
Biological Process	GO:0030183	B cell differentiation	Pou1f1	IMP	MGI:MGI:1856024	Mouse	PMID:9300691
Biological Process	GO:0001708	cell fate specification	Pou1f1	IDA		Mouse	PMID:10367888
Biological Process	GO:0001708	cell fate specification	pou1f1	IMP	ZFIN:ZDB-GENO-040715-2	Zfish	PMID:14988429
Biological Process	GO:0001708	cell fate specification	pou1f1	IMP	ZFIN:ZDB-GENO-040715-2	Zfish	PMID:14752054
Biological Process	GO:0001708	cell fate specification	pou1f1	IMP	ZFIN:ZDB-GENO-040715-3	Zfish	PMID:14752054
Biological Process	GO:0001708	cell fate specification	pou1f1	IMP	ZFIN:ZDB-GENO-040715-3	Zfish	PMID:14988429
Biological Process	GO:0008283	cell population proliferation	Pou1f1	IMP	MGI:MGI:1856024	Mouse	PMID:16556738
Biological Process	GO:0008340	determination of adult lifespan	Pou1f1	IMP	MGI:MGI:1856024	Mouse	PMID:11371619
Biological Process	GO:0008340	determination of adult lifespan	Pou1f1	IMP	MGI:MGI:1856025	Mouse	PMID:11371619
Biological Process	GO:0032959	inositol trisphosphate biosynthetic process	Pou1f1	IMP	MGI:MGI:1856025	Mouse	PMID:11371619
Biological Process	GO:0032959	inositol trisphosphate biosynthetic process	Pou1f1	IMP	MGI:MGI:1856024	Mouse	PMID:11371619
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pou1f1	IGI	UniProtKB:P10037	Rat	PMID:16030140|RGD:1601441
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pou1f1	IGI	UniProtKB:Q60974	Rat	PMID:16030140|RGD:1601441
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pou1f1	IDA		Rat	PMID:17021049|RGD:1601438
Biological Process	GO:0021983	pituitary gland development	Pou1f1	IMP	MGI:MGI:1856024	Mouse	PMID:16556738
Biological Process	GO:0008284	positive regulation of cell population proliferation	Pou1f1	IMP	MGI:MGI:1856024	Mouse	PMID:16556738
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Pou1f1	IDA		Mouse	PMID:11891224
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Pou1f1	IDA		Rat	PMID:8370519|RGD:61786
Biological Process	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	Pou1f1	IMP	MGI:MGI:1856025	Mouse	PMID:11371619
Biological Process	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	Pou1f1	IMP	MGI:MGI:1856024	Mouse	PMID:11371619
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Pou1f1	IMP	MGI:MGI:2158737	Mouse	PMID:17015435
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Pou1f1	IMP	MGI:MGI:1856024	Mouse	PMID:7390396
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	POU1F1	IDA		Human	PMID:26612202
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	POU1F1	IDA		Human	PMID:9482665
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	POU1F1	IDA		Human	PMID:9685346
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou1f1	IDA		Mouse	PMID:11447259
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou1f1	IGI	MGI:MGI:1891158	Mouse	PMID:11447259
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou1f1	IGI	MGI:MGI:95662	Mouse	PMID:9305891
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou1f1	IGI	MGI:MGI:1342291	Mouse	PMID:10431247
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou1f1	IDA		Mouse	PMID:8391647
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou1f1	IGI	MGI:MGI:102673	Mouse	PMID:10431247
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou1f1	IDA		Rat	PMID:17021049|RGD:1601438
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou1f1	IMP		Rat	PMID:19887646|RGD:8661635
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou1f1	IDA		Rat	PMID:8370519|RGD:61786
Biological Process	GO:0006355	regulation of DNA-templated transcription	POU1F1	IDA		Human	PMID:11301317
Biological Process	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	Pou1f1	IMP	MGI:MGI:1856024	Mouse	PMID:7390396
Biological Process	GO:0060133	somatotropin secreting cell development	Pou1f1	IMP	MGI:MGI:2158737	Mouse	PMID:17015435
Biological Process	GO:0060126	somatotropin secreting cell differentiation	Pou1f1	IMP	MGI:MGI:1856024	Mouse	PMID:1334535
Biological Process	GO:0060126	somatotropin secreting cell differentiation	Pou1f1	IMP	MGI:MGI:1856024	Mouse	PMID:6194978

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern