Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POU2F1
  • Mouse genes Pou2f1
  • Rat genes Pou2f1
  • Zfish genes pou2f1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pou2f1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Pou2f1	IDA		Mouse	PMID:16735694
Molecular Function	GO:0003682	chromatin binding	Pou2f1	IDA		Rat	PMID:17481938|RGD:9743917
Molecular Function	GO:0003677	DNA binding	POU2F1	IDA		Human	PMID:9199328
Molecular Function	GO:0003677	DNA binding	Pou2f1	IDA		Mouse	PMID:15024082
Molecular Function	GO:0003677	DNA binding	Pou2f1	IDA		Mouse	PMID:15613485
Molecular Function	GO:0003677	DNA binding	Pou2f1	IDA		Mouse	PMID:9738004
Molecular Function	GO:0003677	DNA binding	Pou2f1	IDA		Mouse	PMID:11937630
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	POU2F1	IMP		Human	PMID:11380252
Molecular Function	GO:0005515	protein binding	POU2F1	IPI	UniProtKB:P51610	Human	PMID:10629049
Molecular Function	GO:0005515	protein binding	POU2F1	IPI	UniProtKB:P08047	Human	PMID:10976766
Molecular Function	GO:0005515	protein binding	POU2F1	IPI	UniProtKB:P06537	Human	PMID:11997177
Molecular Function	GO:0005515	protein binding	POU2F1	IPI	UniProtKB:P19091	Human	PMID:11997177
Molecular Function	GO:0005515	protein binding	POU2F1	IPI	UniProtKB:O15047	Human	PMID:12670868
Molecular Function	GO:0005515	protein binding	POU2F1	IPI	UniProtKB:P08047	Human	PMID:19070619
Molecular Function	GO:0005515	protein binding	POU2F1	IPI	UniProtKB:Q02446	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	POU2F1	IPI	UniProtKB:Q7Z3K3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	POU2F1	IPI	UniProtKB:Q9H4B4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Pou2f1	IPI	PR:P63002	Mouse	PMID:16002402
Molecular Function	GO:0005515	protein binding	Pou2f1	IPI	PR:Q62441	Mouse	PMID:16002402
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	POU2F1	IMP		Human	PMID:10329190
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	POU2F1	IMP		Human	PMID:10541551
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	POU2F1	IMP		Human	PMID:11380252
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	POU2F1	IDA		Human	PMID:25802280
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	POU2F1	IMP		Human	PMID:10541551
Molecular Function	GO:0043565	sequence-specific DNA binding	POU2F1	IDA		Human	PMID:11997177
Molecular Function	GO:0043565	sequence-specific DNA binding	POU2F1	IDA		Human	PMID:7945330
Molecular Function	GO:0043565	sequence-specific DNA binding	POU2F1	IDA		Human	PMID:9242494
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou2f1	IDA		Mouse	PMID:7969117
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou2f1	IDA		Mouse	PMID:8131747
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou2f1	IDA		Mouse	PMID:17140559
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou2f1	IDA		Mouse	PMID:1690859
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou2f1	IDA		Mouse	PMID:8960364
Molecular Function	GO:0005102	signaling receptor binding	Pou2f1	IPI	RGD:736929	Rat	PMID:10383413|RGD:9727451
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Pou2f1	IDA		Rat	PMID:12818430|RGD:731231
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Pou2f1	IDA		Rat	PMID:8632766|RGD:9727455
Cellular Component	GO:0005783	endoplasmic reticulum	POU2F1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	POU2F1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	POU2F1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	POU2F1	IDA		Human	PMID:11891224
Cellular Component	GO:0005634	nucleus	POU2F1	IDA		Human	PMID:9242494
Cellular Component	GO:0005634	nucleus	Pou2f1	IDA		Mouse	PMID:15613485
Cellular Component	GO:0005634	nucleus	Pou2f1	IDA		Mouse	PMID:8131747
Cellular Component	GO:0005634	nucleus	Pou2f1	IDA		Mouse	PMID:11937630
Cellular Component	GO:0005634	nucleus	Pou2f1	IDA		Mouse	PMID:7969117
Cellular Component	GO:0005634	nucleus	Pou2f1	IDA		Mouse	PMID:15024082
Cellular Component	GO:0005634	nucleus	Pou2f1	IDA		Rat	PMID:15942958|RGD:1598733
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	POU2F1	IMP		Human	PMID:10329190
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	POU2F1	IMP		Human	PMID:11380252
Cellular Component	GO:0005667	transcription regulator complex	Pou2f1	IDA		Mouse	PMID:7969117
Cellular Component	GO:0005667	transcription regulator complex	Pou2f1	IDA		Mouse	PMID:12782656
Biological Process	GO:0060235	lens induction in camera-type eye	Pou2f1	IGI	MGI:MGI:98364	Mouse	PMID:17140559
Biological Process	GO:0097421	liver regeneration	Pou2f1	IEP		Rat	PMID:1841628|RGD:9743904
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	POU2F1	IDA		Human	PMID:11891224
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	POU2F1	IDA		Human	PMID:11997177
Biological Process	GO:0010629	negative regulation of gene expression	Pou2f1	IMP		Rat	PMID:28108289|RGD:13464258
Biological Process	GO:0030910	olfactory placode formation	Pou2f1	IGI	MGI:MGI:98364	Mouse	PMID:17140559
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	POU2F1	IGI	UniProtKB:P06492	Human	PMID:11380252
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	POU2F1	IGI	UniProtKB:Q16633	Human	PMID:11380252
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	POU2F1	IMP		Human	PMID:11380252
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	POU2F1	IDA		Human	PMID:15252056
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou2f1	IGI	MGI:MGI:98364	Mouse	PMID:17140559
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou2f1	IDA		Mouse	PMID:16002402
Biological Process	GO:0006366	transcription by RNA polymerase II	Pou2f1	IDA		Mouse	PMID:16002402

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern