Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POU2F2
  • Mouse genes Pou2f2
  • Rat genes Pou2f2
  • Zfish genes pou2f2a,pou2f2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pou2f2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Pou2f2	IDA		Mouse	PMID:14978099
Molecular Function	GO:0003677	DNA binding	Pou2f2	IDA		Mouse	PMID:11937630
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pou2f2	IDA		Mouse	MGI:MGI:3037422|PMID:11937630
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou2f2	IDA		Mouse	MGI:MGI:5450752|PMID:23045607
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou2f2	IDA		Mouse	PMID:14978099
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou2f2	IDA		Mouse	PMID:11937630
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou2f2	IDA		Rat	PMID:9196379|RGD:2290189
Molecular Function	GO:0019904	protein domain specific binding	Pou2f2	IPI	PR:P30681	Mouse	PMID:7720710
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pou2f2	IDA		Mouse	MGI:MGI:3037422|PMID:11937630
Molecular Function	GO:0043565	sequence-specific DNA binding	POU2F2	IDA		Human	PMID:9242494
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou2f2	IDA		Mouse	PMID:7720710
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou2f2	IDA		Mouse	PMID:17141158
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou2f2	IDA		Mouse	PMID:7902581
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou2f2	IDA		Rat	PMID:9196379|RGD:2290189
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	POU2F2	IDA		Human	PMID:28473536
Molecular Function	GO:0015606	spermidine transmembrane transporter activity	Pou2f2	IDA		Mouse	MGI:MGI:7387165|PMID:23458604
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Pou2f2	IDA		Mouse	MGI:MGI:5450752|PMID:23045607
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	POU2F2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	POU2F2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	POU2F2	IDA		Human	PMID:9242494
Cellular Component	GO:0005634	nucleus	Pou2f2	IDA		Mouse	PMID:14978099
Cellular Component	GO:0005634	nucleus	Pou2f2	IDA		Mouse	PMID:11937630
Cellular Component	GO:0005634	nucleus	Pou2f2	IDA		Rat	PMID:9196379|RGD:2290189
Biological Process	GO:0048469	cell maturation	Pou2f2	IMP	MGI:MGI:3037094	Mouse	PMID:14978099
Biological Process	GO:0098586	cellular response to virus	Pou2f2	IMP		Mouse	MGI:MGI:5450752|PMID:23045607
Biological Process	GO:0002377	immunoglobulin production	Pou2f2	IMP	MGI:MGI:3037094	Mouse	PMID:14978099
Biological Process	GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	Pou2f2	IMP	MGI:MGI:3028896	Mouse	PMID:8096198
Biological Process	GO:0002335	mature B cell differentiation	Pou2f2	IMP	MGI:MGI:3028896	Mouse	PMID:8096198
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Pou2f2	IDA		Mouse	PMID:11937630
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Pou2f2	IDA		Mouse	MGI:MGI:5450752|PMID:23045607
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou2f2	IDA		Mouse	MGI:MGI:3037422|PMID:11937630
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou2f2	IDA		Mouse	MGI:MGI:5450752|PMID:23045607
Biological Process	GO:0006355	regulation of DNA-templated transcription	Pou2f2	IDA		Mouse	PMID:14978099
Biological Process	GO:0006355	regulation of DNA-templated transcription	Pou2f2	IDA		Rat	PMID:9196379|RGD:2290189
Biological Process	GO:0015848	spermidine transport	Pou2f2	IDA		Mouse	MGI:MGI:7387165|PMID:23458604

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern