Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POU2F3
  • Mouse genes Pou2f3
  • Rat genes Pou2f3
  • Zfish genes pou2f3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pou2f3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Pou2f3	IDA		Mouse	PMID:7682011
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	POU2F3	IDA		Human	PMID:12624109
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	POU2F3	IMP		Human	PMID:12624109
Molecular Function	GO:0042802	identical protein binding	Pou2f3	IPI	PR:P31362	Mouse	PMID:7682011
Molecular Function	GO:0005515	protein binding	POU2F3	IPI	UniProtKB:P78545	Human	PMID:12624109
Molecular Function	GO:0005515	protein binding	POU2F3	IPI	UniProtKB:A8K830	Human	PMID:35576971
Molecular Function	GO:0005515	protein binding	POU2F3	IPI	UniProtKB:Q8IXP5	Human	PMID:35576971
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	POU2F3	IMP		Human	PMID:12624109
Molecular Function	GO:0043565	sequence-specific DNA binding	POU2F3	IDA		Human	PMID:9242494
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou2f3	IDA		Mouse	PMID:8224904
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	POU2F3	IDA		Human	PMID:28473536
Cellular Component	GO:0005829	cytosol	POU2F3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	POU2F3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	POU2F3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	POU2F3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	POU2F3	IDA		Human	PMID:9242494
Cellular Component	GO:0005634	nucleus	Pou2f3	IDA		Mouse	MGI:MGI:894946|PMID:9242494
Cellular Component	GO:0005886	plasma membrane	POU2F3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005667	transcription regulator complex	Pou2f3	IDA		Mouse	PMID:7682011
Biological Process	GO:0030154	cell differentiation	Pou2f3	IMP		Mouse	MGI:MGI:6103332|PMID:29216297
Biological Process	GO:0008544	epidermis development	Pou2f3	IGI	MGI:MGI:101896	Mouse	PMID:9242494
Biological Process	GO:0008544	epidermis development	Pou2f3	IDA		Rat	PMID:7682011|RGD:729468
Biological Process	GO:0030216	keratinocyte differentiation	POU2F3	IDA		Human	PMID:11329378
Biological Process	GO:0030216	keratinocyte differentiation	Pou2f3	IGI	MGI:MGI:101896	Mouse	PMID:9242494
Biological Process	GO:0043922	negative regulation by host of viral transcription	POU2F3	IDA		Human	PMID:14645924
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	POU2F3	IDA		Human	PMID:12624109
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou2f3	IDA		Mouse	PMID:7682011
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Pou2f3	IDA		Rat	PMID:7682011|RGD:729468
Biological Process	GO:0042060	wound healing	Pou2f3	IMP	MGI:MGI:2450109	Mouse	PMID:9242494

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern