Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POU3F1
  • Mouse genes Pou3f1
  • Rat genes Pou3f1
  • Zfish genes pou3f1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pou3f1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Pou3f1	IDA		Mouse	PMID:12782656
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou3f1	IDA		Rat	PMID:9196379|RGD:2290189
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Pou3f1	IDA		Rat	PMID:9632656|RGD:68859
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Pou3f1	IDA		Rat	PMID:1705013|RGD:729433
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pou3f1	IDA		Rat	PMID:1705013|RGD:729433
Molecular Function	GO:0043565	sequence-specific DNA binding	POU3F1	IDA		Human	PMID:9242494
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou3f1	IDA		Rat	PMID:9196379|RGD:2290189
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	POU3F1	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	POU3F1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Pou3f1	IDA		Mouse	MGI:MGI:3531619|PMID:15713637
Cellular Component	GO:0005634	nucleus	Pou3f1	IDA		Mouse	PMID:22992956
Cellular Component	GO:0005634	nucleus	Pou3f1	IDA		Rat	PMID:9196379|RGD:2290189
Cellular Component	GO:0005667	transcription regulator complex	Pou3f1	IDA		Mouse	PMID:12782656
Biological Process	GO:0008544	epidermis development	Pou3f1	IGI	MGI:MGI:102565	Mouse	PMID:9242494
Biological Process	GO:0030900	forebrain development	Pou3f1	IMP	MGI:MGI:3574356	Mouse	PMID:19527706
Biological Process	GO:0010001	glial cell differentiation	Pou3f1	IDA		Rat	PMID:1975954|RGD:729555
Biological Process	GO:0030216	keratinocyte differentiation	Pou3f1	IGI	MGI:MGI:102565	Mouse	PMID:9242494
Biological Process	GO:0042552	myelination	Pou3f1	IMP	MGI:MGI:2387951	Mouse	PMID:15282162
Biological Process	GO:0022011	myelination in peripheral nervous system	Pou3f1	IGI	MGI:MGI:101895	Mouse	PMID:12782656
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Pou3f1	IDA		Rat	PMID:1975954|RGD:729555
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pou3f1	IDA		Rat	PMID:1705013|RGD:729433
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Pou3f1	IDA		Mouse	MGI:MGI:3531619|PMID:15713637
Biological Process	GO:0010628	positive regulation of gene expression	Pou3f1	IDA		Mouse	MGI:MGI:3531619|PMID:15713637
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou3f1	IDA		Rat	PMID:9632656|RGD:68859
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou3f1	IGI	UniProtKB:P0C1G9	Rat	PMID:9632656|RGD:68859
Biological Process	GO:0006355	regulation of DNA-templated transcription	Pou3f1	IDA		Rat	PMID:9196379|RGD:2290189
Biological Process	GO:0014044	Schwann cell development	Pou3f1	IMP	MGI:MGI:2387953	Mouse	PMID:12782656

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern