Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POU3F3
  • Mouse genes Pou3f3
  • Rat genes Pou3f3
  • Zfish genes pou3f3a,pou3f3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pou3f3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Pou3f3	IDA		Mouse	PMID:15465489
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou3f3	IDA		Rat	PMID:9405434|RGD:633620
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Pou3f3	IDA		Rat	PMID:9632656|RGD:68859
Molecular Function	GO:0071837	HMG box domain binding	Pou3f3	IPI	UniProtKB:O55170|UniProtKB:Q05066	Mouse	MGI:MGI:5284787|PMID:16582099
Molecular Function	GO:0005515	protein binding	Pou3f3	IPI	UniProtKB:P06537|UniProtKB:P19091	Mouse	MGI:MGI:4362014|PMID:11997177
Molecular Function	GO:0042803	protein homodimerization activity	POU3F3	IDA		Human	PMID:31303265
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou3f3	IDA		Mouse	MGI:MGI:4362014|PMID:11997177
Cellular Component	GO:0005654	nucleoplasm	POU3F3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	POU3F3	IDA		Human	PMID:31303265
Cellular Component	GO:0005634	nucleus	Pou3f3	IDA		Mouse	PMID:8663425
Cellular Component	GO:0005634	nucleus	Pou3f3	IMP		Rat	PMID:15713637|RGD:8553669
Cellular Component	GO:0005634	nucleus	Pou3f3	IDA		Rat	PMID:9405434|RGD:633620
Cellular Component	GO:0005634	nucleus	Pou3f3	IDA		Rat	PMID:9632656|RGD:68859
Biological Process	GO:0021799	cerebral cortex radially oriented cell migration	Pou3f3	IGI	MGI:MGI:101895	Mouse	PMID:12130536
Biological Process	GO:0048878	chemical homeostasis	Pou3f3	IMP	MGI:MGI:3712282	Mouse	PMID:17264314
Biological Process	GO:0021869	forebrain ventricular zone progenitor cell division	Pou3f3	IGI	MGI:MGI:101895	Mouse	PMID:12130536
Biological Process	GO:0001822	kidney development	Pou3f3	IMP	MGI:MGI:2673387	Mouse	PMID:12925600
Biological Process	GO:0001822	kidney development	Pou3f3	IMP	MGI:MGI:3712282	Mouse	PMID:17264314
Biological Process	GO:0072218	metanephric ascending thin limb development	Pou3f3	IMP		Mouse	MGI:MGI:2669573|PMID:12925600
Biological Process	GO:0072240	metanephric DCT cell differentiation	Pou3f3	IMP		Mouse	MGI:MGI:2669573|PMID:12925600
Biological Process	GO:0072236	metanephric loop of Henle development	Pou3f3	IMP		Mouse	MGI:MGI:2669573|PMID:12925600
Biological Process	GO:0072227	metanephric macula densa development	Pou3f3	IMP		Mouse	MGI:MGI:2669573|PMID:12925600
Biological Process	GO:0072233	metanephric thick ascending limb development	Pou3f3	IMP		Mouse	MGI:MGI:2669573|PMID:12925600
Biological Process	GO:0043066	negative regulation of apoptotic process	Pou3f3	IMP		Mouse	MGI:MGI:2669573|PMID:12925600
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Pou3f3	IDA		Mouse	MGI:MGI:4362014|PMID:11997177
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pou3f3	IGI	UniProtKB:P0C1G9	Rat	PMID:9632656|RGD:68859
Biological Process	GO:0008284	positive regulation of cell population proliferation	Pou3f3	IMP		Mouse	MGI:MGI:2669573|PMID:12925600
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	POU3F3	IDA		Human	PMID:31303265
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Pou3f3	IMP		Mouse	MGI:MGI:2669573|PMID:12925600
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Pou3f3	IGI	UniProtKB:P0C1G9	Rat	PMID:9632656|RGD:68859
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Pou3f3	IMP		Rat	PMID:15713637|RGD:8553669
Biological Process	GO:0010628	positive regulation of gene expression	Pou3f3	IMP		Rat	PMID:15713637|RGD:8553669
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou3f3	IGI	MGI:MGI:96919	Mouse	PMID:17141158
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou3f3	IDA		Rat	PMID:9405434|RGD:633620
Biological Process	GO:0071918	urea transmembrane transport	Pou3f3	IMP	MGI:MGI:3712282	Mouse	PMID:17264314

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern