Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POU3F4
  • Mouse genes Pou3f4
  • Rat genes Pou3f4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pou3f4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou3f4	IDA		Rat	PMID:9372951|RGD:1599157
Molecular Function	GO:0003690	double-stranded DNA binding	Pou3f4	IDA		Rat	PMID:9372951|RGD:1599157
Molecular Function	GO:0003680	minor groove of adenine-thymine-rich DNA binding	Pou3f4	IDA		Rat	PMID:9372951|RGD:1599157
Molecular Function	GO:0005515	protein binding	POU3F4	IPI	UniProtKB:Q00839	Human	PMID:9105675
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Pou3f4	IDA		Mouse	MGI:MGI:3703099|PMID:17141158
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou3f4	IDA		Mouse	PMID:17141158
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	POU3F4	IDA		Human	PMID:28473536
Cellular Component	GO:0005622	intracellular anatomical structure	Pou3f4	IDA		Mouse	PMID:10868931
Cellular Component	GO:0005634	nucleus	Pou3f4	IDA		Rat	PMID:9372951|RGD:1599157
Biological Process	GO:0090103	cochlea morphogenesis	Pou3f4	IGI	UniProtKB:P70323	Mouse	MGI:MGI:5284768|PMID:18231833
Biological Process	GO:0021879	forebrain neuron differentiation	Pou3f4	IMP		Mouse	PMID:9889200
Biological Process	GO:0048839	inner ear development	Pou3f4	IMP	MGI:MGI:1857990	Mouse	PMID:15655183
Biological Process	GO:0048839	inner ear development	Pou3f4	IMP	MGI:MGI:1856631	Mouse	PMID:10587581
Biological Process	GO:2001054	negative regulation of mesenchymal cell apoptotic process	Pou3f4	IGI	UniProtKB:P70323	Mouse	MGI:MGI:5284768|PMID:18231833
Biological Process	GO:0007605	sensory perception of sound	Pou3f4	IMP	MGI:MGI:1856631	Mouse	PMID:10587581
Biological Process	GO:0007605	sensory perception of sound	Pou3f4	IMP	MGI:MGI:1857990	Mouse	PMID:15574296
Biological Process	GO:0006366	transcription by RNA polymerase II	Pou3f4	IDA		Rat	PMID:9372951|RGD:1599157

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern