Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pou4f1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes POU4F1
- Mouse genes Pou4f1
- Rat genes Pou4f1
- Zfish genes pou4f1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pou4f1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Pou4f1	IGI	UniProtKB:P70425	Mouse	MGI:MGI:5784992\|PMID:12934100
Molecular Function	GO:0003677	DNA binding	Pou4f1	IDA		Mouse	PMID:15492043
Molecular Function	GO:0003677	DNA binding	Pou4f1	IDA		Mouse	PMID:12810599
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pou4f1	IMP		Mouse	MGI:MGI:5825431\|PMID:17145718
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pou4f1	IDA		Mouse	MGI:MGI:2663581\|PMID:12810599
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pou4f1	IMP		Mouse	MGI:MGI:2663581\|PMID:12810599
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pou4f1	IDA		Mouse	MGI:MGI:6355477\|PMID:10329733
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pou4f1	IGI	UniProtKB:O15350	Mouse	MGI:MGI:5688842\|PMID:18421303
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Pou4f1	IDA		Mouse	MGI:MGI:3807433\|PMID:18368538
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:12810599
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	POU4F1	IDA		Human	PMID:23805044
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Pou4f1	IDA		Mouse	MGI:MGI:4454975\|PMID:20096094
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Pou4f1	IGI	UniProtKB:O15350	Mouse	MGI:MGI:5688842\|PMID:18421303
Molecular Function	GO:0051020	GTPase binding	Pou4f1	IPI	UniProtKB:P70425	Mouse	MGI:MGI:5784992\|PMID:12934100
Molecular Function	GO:0005515	protein binding	POU4F1	IPI	UniProtKB:Q9UPY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pou4f1	IPI	UniProtKB:Q63934-2	Mouse	MGI:MGI:78067\|PMID:8537352
Molecular Function	GO:0005515	protein binding	Pou4f1	IPI	UniProtKB:P19785	Mouse	MGI:MGI:5825439\|PMID:9448000
Molecular Function	GO:0005515	protein binding	Pou4f1	IPI	PR:Q9QZR5	Mouse	PMID:15492043
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pou4f1	IDA		Mouse	MGI:MGI:4454975\|PMID:20096094
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pou4f1	IDA		Mouse	MGI:MGI:3703481\|PMID:17196582
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pou4f1	IDA		Mouse	MGI:MGI:2663581\|PMID:12810599
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Pou4f1	IPI	UniProtKB:O15350	Mouse	MGI:MGI:5688842\|PMID:18421303
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Pou4f1	IPI	UniProtKB:P10361	Rat	PMID:10329733\|RGD:14697712
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou4f1	IDA		Mouse	MGI:MGI:5795831\|PMID:8621561
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou4f1	IDA		Mouse	MGI:MGI:5825441\|PMID:7935408
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou4f1	IDA		Mouse	MGI:MGI:5825429\|PMID:17668438
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou4f1	IDA		Mouse	MGI:MGI:64462\|PMID:8290353
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	POU4F1	IDA		Human	PMID:28473536
Molecular Function	GO:0003697	single-stranded DNA binding	Pou4f1	IDA		Mouse	MGI:MGI:5795831\|PMID:8621561
Cellular Component	GO:0000785	chromatin	Pou4f1	IDA		Mouse	MGI:MGI:3703481\|PMID:17196582
Cellular Component	GO:0000785	chromatin	Pou4f1	IDA		Mouse	MGI:MGI:4454975\|PMID:20096094
Cellular Component	GO:0005737	cytoplasm	Pou4f1	IDA		Mouse	MGI:MGI:5825429\|PMID:17668438
Cellular Component	GO:0043005	neuron projection	Pou4f1	IDA		Mouse	PMID:19906978
Cellular Component	GO:0005634	nucleus	Pou4f1	IDA		Mouse	MGI:MGI:5142400\|PMID:7623109
Cellular Component	GO:0005634	nucleus	Pou4f1	IDA		Mouse	MGI:MGI:5825429\|PMID:17668438
Cellular Component	GO:0005634	nucleus	Pou4f1	IDA		Mouse	MGI:MGI:6356503\|PMID:15532030
Cellular Component	GO:0005634	nucleus	Pou4f1	IDA		Mouse	MGI:MGI:5688842\|PMID:18421303
Cellular Component	GO:0005634	nucleus	Pou4f1	IDA		Mouse	PMID:16752387
Cellular Component	GO:0005634	nucleus	Pou4f1	IDA		Mouse	PMID:12810599
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	Pou4f1	IDA		Mouse	MGI:MGI:6355477\|PMID:10329733
Biological Process	GO:0021535	cell migration in hindbrain	Pou4f1	IMP	MGI:MGI:3512302	Mouse	PMID:8955272
Biological Process	GO:0071345	cellular response to cytokine stimulus	Pou4f1	IDA		Mouse	MGI:MGI:5825429\|PMID:17668438
Biological Process	GO:0071392	cellular response to estradiol stimulus	Pou4f1	IDA		Mouse	MGI:MGI:5825439\|PMID:9448000
Biological Process	GO:0021953	central nervous system neuron differentiation	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:8876243
Biological Process	GO:0021953	central nervous system neuron differentiation	Pou4f1	IMP	MGI:MGI:3512302	Mouse	PMID:8955272
Biological Process	GO:0021986	habenula development	Pou4f1	IMP	MGI:MGI:3512089	Mouse	PMID:19906978
Biological Process	GO:0021986	habenula development	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:19906978
Biological Process	GO:0007507	heart development	Pou4f1	IGI	UniProtKB:Q63934	Mouse	MGI:MGI:6158788\|PMID:28594399
Biological Process	GO:0007507	heart development	pou4f1	IGI	ZFIN:ZDB-MRPHLNO-170801-1,ZFIN:ZDB-MRPHLNO-170801-2	Zfish	PMID:28594399
Biological Process	GO:0060384	innervation	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:19906978
Biological Process	GO:0060384	innervation	Pou4f1	IMP	MGI:MGI:3512089	Mouse	PMID:19906978
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	Pou4f1	IMP		Mouse	MGI:MGI:5825431\|PMID:17145718
Biological Process	GO:0007498	mesoderm development	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:19877281
Biological Process	GO:0043066	negative regulation of apoptotic process	Pou4f1	IGI	UniProtKB:P04637	Mouse	MGI:MGI:6467921\|PMID:12433990
Biological Process	GO:0043066	negative regulation of apoptotic process	Pou4f1	IGI	UniProtKB:O15350	Mouse	MGI:MGI:5688842\|PMID:18421303
Biological Process	GO:0043066	negative regulation of apoptotic process	Pou4f1	IGI	UniProtKB:P04637	Mouse	MGI:MGI:6467925\|PMID:12203124
Biological Process	GO:0010629	negative regulation of gene expression	Pou4f1	IMP		Mouse	MGI:MGI:6158788\|PMID:28594399
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Pou4f1	IMP		Mouse	MGI:MGI:4454975\|PMID:20096094
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Pou4f1	IMP		Rat	PMID:11053412\|RGD:724643
Biological Process	GO:0043069	negative regulation of programmed cell death	Pou4f1	IMP		Mouse	MGI:MGI:5825431\|PMID:17145718
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pou4f1	IMP		Mouse	MGI:MGI:4454767\|PMID:17239249
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pou4f1	IGI	UniProtKB:O15350	Mouse	MGI:MGI:5688842\|PMID:18421303
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pou4f1	IDA		Mouse	MGI:MGI:4367920\|PMID:19877281
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:19877281
Biological Process	GO:0007399	nervous system development	Pou4f1	IDA		Mouse	PMID:12810599
Biological Process	GO:0051402	neuron apoptotic process	Pou4f1	IGI	MGI:MGI:1314872	Mouse	PMID:15492043
Biological Process	GO:0030182	neuron differentiation	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:16040009
Biological Process	GO:0048665	neuron fate specification	Pou4f1	IMP		Mouse	MGI:MGI:4454975\|PMID:20096094
Biological Process	GO:0048665	neuron fate specification	Pou4f1	IMP		Mouse	MGI:MGI:4367920\|PMID:19877281
Biological Process	GO:0001764	neuron migration	Pou4f1	IMP	MGI:MGI:3512302	Mouse	PMID:8955272
Biological Process	GO:0031175	neuron projection development	Pou4f1	IDA		Mouse	MGI:MGI:85265\|PMID:8972215
Biological Process	GO:0048935	peripheral nervous system neuron development	Pou4f1	IMP		Mouse	MGI:MGI:4454767\|PMID:17239249
Biological Process	GO:0048935	peripheral nervous system neuron development	Pou4f1	IMP		Mouse	MGI:MGI:4367920\|PMID:19877281
Biological Process	GO:0048935	peripheral nervous system neuron development	Pou4f1	IMP		Mouse	MGI:MGI:4454975\|PMID:20096094
Biological Process	GO:0048935	peripheral nervous system neuron development	Pou4f1	IGI	MGI:MGI:101791	Mouse	PMID:21734270
Biological Process	GO:0048934	peripheral nervous system neuron differentiation	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:8876243
Biological Process	GO:0048934	peripheral nervous system neuron differentiation	Pou4f1	IMP	MGI:MGI:3512302	Mouse	PMID:8955272
Biological Process	GO:0010628	positive regulation of gene expression	Pou4f1	IDA		Mouse	MGI:MGI:85265\|PMID:8972215
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Pou4f1	IGI	MGI:MGI:1314872	Mouse	PMID:15492043
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	Pou4f1	IMP		Mouse	MGI:MGI:5825429\|PMID:17668438
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou4f1	IDA		Mouse	MGI:MGI:6355477\|PMID:10329733
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou4f1	IDA		Mouse	MGI:MGI:3807433\|PMID:18368538
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou4f1	IMP		Mouse	MGI:MGI:4454767\|PMID:17239249
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou4f1	IGI	UniProtKB:O15350	Mouse	MGI:MGI:5688842\|PMID:18421303
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou4f1	IMP		Mouse	MGI:MGI:5825441\|PMID:7935408
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou4f1	IGI	UniProtKB:P70425	Mouse	MGI:MGI:5784992\|PMID:12934100
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou4f1	IMP		Mouse	MGI:MGI:2663581\|PMID:12810599
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:19877281
Biological Process	GO:2000679	positive regulation of transcription regulatory region DNA binding	Pou4f1	IDA		Mouse	MGI:MGI:5825439\|PMID:9448000
Biological Process	GO:0051355	proprioception involved in equilibrioception	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:8876243
Biological Process	GO:0051355	proprioception involved in equilibrioception	Pou4f1	IMP	MGI:MGI:3512302	Mouse	PMID:8955272
Biological Process	GO:0051726	regulation of cell cycle	Pou4f1	IGI	UniProtKB:P04637	Mouse	MGI:MGI:6467925\|PMID:12203124
Biological Process	GO:0051726	regulation of cell cycle	Pou4f1	IGI	UniProtKB:P04637	Mouse	MGI:MGI:6467921\|PMID:12433990
Biological Process	GO:0051726	regulation of cell cycle	Pou4f1	IGI	UniProtKB:O15350	Mouse	MGI:MGI:5688842\|PMID:18421303
Biological Process	GO:0051726	regulation of cell cycle	Pou4f1	IMP		Mouse	MGI:MGI:5825431\|PMID:17145718
Biological Process	GO:0051090	regulation of DNA-binding transcription factor activity	Pou4f1	IDA		Mouse	MGI:MGI:5825439\|PMID:9448000
Biological Process	GO:0006355	regulation of DNA-templated transcription	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:12810599
Biological Process	GO:0006355	regulation of DNA-templated transcription	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:19906978
Biological Process	GO:0050767	regulation of neurogenesis	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:19877281
Biological Process	GO:0048880	sensory system development	Pou4f1	IMP		Mouse	MGI:MGI:4454975\|PMID:20096094
Biological Process	GO:0007283	spermatogenesis	Pou4f1	IEP		Rat	PMID:11470235\|RGD:8693587
Biological Process	GO:0001967	suckling behavior	Pou4f1	IMP	MGI:MGI:2387665	Mouse	PMID:8876243
Biological Process	GO:0001967	suckling behavior	Pou4f1	IMP	MGI:MGI:3512302	Mouse	PMID:8955272
Biological Process	GO:0021559	trigeminal nerve development	Pou4f1	IMP		Mouse	MGI:MGI:4367920\|PMID:19877281
Biological Process	GO:0003223	ventricular compact myocardium morphogenesis	Pou4f1	IMP		Mouse	MGI:MGI:3807433\|PMID:18368538

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.