Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POU4F3
  • Mouse genes Pou4f3
  • Rat genes Pou4f3
  • Zfish genes pou4f3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pou4f3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	POU4F3	IDA		Human	PMID:15465029
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	POU4F3	IDA		Human	PMID:23805044
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pou4f3	IDA		Mouse	PMID:15465029
Molecular Function	GO:0005515	protein binding	POU4F3	IPI	UniProtKB:O15496	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU4F3	IPI	UniProtKB:P0CG21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU4F3	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU4F3	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POU4F3	IPI	UniProtKB:Q9H596	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pou4f3	IPI	UniProtKB:P61372	Mouse	MGI:MGI:5825419|PMID:24643061
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	POU4F3	IDA		Human	PMID:15465029
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou4f3	IDA		Mouse	MGI:MGI:5825441|PMID:7935408
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou4f3	IDA		Mouse	MGI:MGI:64462|PMID:8290353
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	POU4F3	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	POU4F3	IDA		Human	PMID:28790396
Cellular Component	GO:0005654	nucleoplasm	POU4F3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	POU4F3	IDA		Human	PMID:28790396
Cellular Component	GO:0005634	nucleus	Pou4f3	IDA		Mouse	MGI:MGI:5142400|PMID:7623109
Cellular Component	GO:0005634	nucleus	Pou4f3	IDA		Mouse	PMID:9735355
Cellular Component	GO:0005634	nucleus	Pou4f3	IDA		Mouse	PMID:9256502
Biological Process	GO:0048675	axon extension	Pou4f3	IGI	MGI:MGI:102524	Mouse	PMID:11807038
Biological Process	GO:0007420	brain development	pou4f3	IEP		Zfish	PMID:15042710
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Pou4f3	IMP	MGI:MGI:2176270	Mouse	PMID:8637595
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Pou4f3	IMP	MGI:MGI:1857425	Mouse	PMID:12585968
Biological Process	GO:0048839	inner ear development	Pou4f3	IMP	MGI:MGI:1857425	Mouse	PMID:9735355
Biological Process	GO:0048839	inner ear development	Pou4f3	IMP	MGI:MGI:1857425	Mouse	PMID:9256502
Biological Process	GO:0042472	inner ear morphogenesis	Pou4f3	IMP	MGI:MGI:1857425	Mouse	PMID:12585968
Biological Process	GO:0060113	inner ear receptor cell differentiation	Pou4f3	IMP	MGI:MGI:1857425	Mouse	PMID:9256502
Biological Process	GO:0060113	inner ear receptor cell differentiation	Pou4f3	IMP	MGI:MGI:1857425	Mouse	PMID:9735355
Biological Process	GO:0050885	neuromuscular process controlling balance	Pou4f3	IMP	MGI:MGI:2176270	Mouse	PMID:8637595
Biological Process	GO:0050885	neuromuscular process controlling balance	Pou4f3	IMP	MGI:MGI:1857425	Mouse	PMID:9256502
Biological Process	GO:0050885	neuromuscular process controlling balance	Pou4f3	IGI	MGI:MGI:102524	Mouse	PMID:11807038
Biological Process	GO:0051402	neuron apoptotic process	Pou4f3	IMP	MGI:MGI:1857425	Mouse	PMID:9735355
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	POU4F3	IDA		Human	PMID:15465029
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	POU4F3	IDA		Human	PMID:23805044
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pou4f3	IMP		Mouse	MGI:MGI:5825441|PMID:7935408
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Pou4f3	IDA		Mouse	PMID:15465029
Biological Process	GO:0031290	retinal ganglion cell axon guidance	Pou4f3	IGI	MGI:MGI:102524	Mouse	PMID:11807038
Biological Process	GO:0007605	sensory perception of sound	Pou4f3	IGI	MGI:MGI:102524	Mouse	PMID:11807038
Biological Process	GO:0007605	sensory perception of sound	Pou4f3	IMP	MGI:MGI:1857425	Mouse	PMID:9256502
Biological Process	GO:0007605	sensory perception of sound	Pou4f3	IMP	MGI:MGI:2176270	Mouse	PMID:8637595
Biological Process	GO:0021562	vestibulocochlear nerve development	Pou4f3	IMP	MGI:MGI:1857425	Mouse	PMID:12585968

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern