Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POU5F2
  • Mouse genes Pou5f2
  • Rat genes Pou5f2
  • Zfish genes pou5f3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pou5f2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	pou5f3	IDA		Zfish	PMID:30674556
Molecular Function	GO:0003682	chromatin binding	pou5f3	IDA		Zfish	PMID:24643012
Molecular Function	GO:0003700	DNA-binding transcription factor activity	pou5f3	IGI	ZFIN:ZDB-GENE-011026-1	Zfish	PMID:14723850
Molecular Function	GO:0005515	protein binding	POU5F2	IPI	UniProtKB:Q3LI66	Human	PMID:32296183
Molecular Function	GO:0046982	protein heterodimerization activity	pou5f3	IPI	ZFIN:ZDB-GENE-010108-1	Zfish	PMID:23364327
Molecular Function	GO:0046982	protein heterodimerization activity	pou5f3	IPI	ZFIN:ZDB-GENE-011026-1	Zfish	PMID:23364327
Molecular Function	GO:0043565	sequence-specific DNA binding	Pou5f2	IDA		Mouse	PMID:7902581
Molecular Function	GO:0043565	sequence-specific DNA binding	pou5f3	IPI	ZFIN:ZDB-GENE-980526-102	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	pou5f3	IPI	ZFIN:ZDB-GENE-030909-1	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	pou5f3	IDA		Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	pou5f3	IPI	ZFIN:ZDB-GENE-980526-485	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	pou5f3	IPI	ZFIN:ZDB-GENE-980526-333	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	pou5f3	IPI	ZFIN:ZDB-GENE-980605-4	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	pou5f3	IPI	ZFIN:ZDB-GENE-010111-1	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	pou5f3	IPI	ZFIN:ZDB-GENE-030131-5486	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	pou5f3	IPI	ZFIN:ZDB-GENE-010416-1	Zfish	PMID:23950494
Biological Process	GO:0009653	anatomical structure morphogenesis	pou5f3	IMP	ZFIN:ZDB-GENO-020625-1	Zfish	PMID:11861475
Biological Process	GO:0009653	anatomical structure morphogenesis	pou5f3	IMP	ZFIN:ZDB-GENO-020426-1	Zfish	PMID:11861475
Biological Process	GO:0007420	brain development	pou5f3	IMP	ZFIN:ZDB-GENO-020625-1	Zfish	PMID:11861475
Biological Process	GO:0007420	brain development	pou5f3	IMP	ZFIN:ZDB-GENO-020426-1	Zfish	PMID:11861475
Biological Process	GO:0007420	brain development	pou5f3	IMP	ZFIN:ZDB-GENO-050317-6	Zfish	PMID:15593329
Biological Process	GO:0035284	brain segmentation	pou5f3	IMP	ZFIN:ZDB-GENO-980202-270	Zfish	PMID:11923201
Biological Process	GO:0035284	brain segmentation	pou5f3	IMP	ZFIN:ZDB-GENO-020117-1	Zfish	PMID:11923201
Biological Process	GO:0043697	cell dedifferentiation	pou5f3	IMP	ZFIN:ZDB-MRPHLNO-200330-1	Zfish	PMID:31594822
Biological Process	GO:0006338	chromatin remodeling	pou5f3	IMP	ZFIN:ZDB-GENO-221020-6	Zfish	PMID:31940339
Biological Process	GO:0009953	dorsal/ventral pattern formation	pou5f3	IMP	ZFIN:ZDB-GENO-070223-1	Zfish	PMID:16775002
Biological Process	GO:0007398	ectoderm development	pou5f3	IMP	ZFIN:ZDB-GENO-020426-1	Zfish	PMID:11861475
Biological Process	GO:0007398	ectoderm development	pou5f3	IMP	ZFIN:ZDB-GENO-020625-1	Zfish	PMID:11861475
Biological Process	GO:0009880	embryonic pattern specification	pou5f3	IMP	ZFIN:ZDB-GENO-020625-1	Zfish	PMID:11861475
Biological Process	GO:0009880	embryonic pattern specification	pou5f3	IMP	ZFIN:ZDB-GENO-100414-8	Zfish	PMID:15366005
Biological Process	GO:0009880	embryonic pattern specification	pou5f3	IMP	ZFIN:ZDB-GENO-020426-1	Zfish	PMID:11861475
Biological Process	GO:0001706	endoderm formation	pou5f3	IMP	ZFIN:ZDB-GENO-020117-1	Zfish	PMID:14711414
Biological Process	GO:0001706	endoderm formation	pou5f3	IMP	ZFIN:ZDB-GENO-020426-1	Zfish	PMID:14723850
Biological Process	GO:0090504	epiboly	pou5f3	IMP	ZFIN:ZDB-GENO-110725-7	Zfish	PMID:23484854
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	pou5f3	IMP	ZFIN:ZDB-GENO-081023-3	Zfish	PMID:18215655
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	pou5f3	IMP	ZFIN:ZDB-GENO-081023-1	Zfish	PMID:18215655
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	pou5f3	IMP	ZFIN:ZDB-GENO-081023-2	Zfish	PMID:18215655
Biological Process	GO:0031101	fin regeneration	pou5f3	IMP	ZFIN:ZDB-MRPHLNO-081015-1	Zfish	PMID:20089153
Biological Process	GO:0030902	hindbrain development	pou5f3	IMP	ZFIN:ZDB-GENO-980202-270	Zfish	PMID:11923201
Biological Process	GO:0030902	hindbrain development	pou5f3	IMP	ZFIN:ZDB-GENO-020117-1	Zfish	PMID:11923201
Biological Process	GO:0007498	mesoderm development	pou5f3	IMP	ZFIN:ZDB-GENO-020426-1	Zfish	PMID:11861475
Biological Process	GO:0007498	mesoderm development	pou5f3	IMP	ZFIN:ZDB-GENO-020625-1	Zfish	PMID:11861475
Biological Process	GO:0030917	midbrain-hindbrain boundary development	pou5f3	IMP	ZFIN:ZDB-GENO-980202-270	Zfish	PMID:9007238
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	pou5f3	IMP	ZFIN:ZDB-GENO-020625-1	Zfish	PMID:11861475
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	pou5f3	IMP	ZFIN:ZDB-GENO-020426-1	Zfish	PMID:11861475
Biological Process	GO:0034728	nucleosome organization	pou5f3	IDA		Zfish	PMID:30674556
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	pou5f3	IGI	ZFIN:ZDB-GENE-011026-1	Zfish	PMID:14723850
Biological Process	GO:0044030	regulation of DNA methylation	pou5f3	IGI	ZFIN:ZDB-GENO-090916-1,ZFIN:ZDB-MRPHLNO-081015-1	Zfish	PMID:20850014
Biological Process	GO:0042663	regulation of endodermal cell fate specification	pou5f3	IGI	ZFIN:ZDB-GENE-010108-1,ZFIN:ZDB-GENE-011026-1	Zfish	PMID:23364327
Biological Process	GO:0042663	regulation of endodermal cell fate specification	pou5f3	IGI	ZFIN:ZDB-GENE-011026-1	Zfish	PMID:23364327
Biological Process	GO:0010468	regulation of gene expression	pou5f3	IMP	ZFIN:ZDB-GENO-110725-7	Zfish	PMID:24643012

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern