Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPFIA2
  • Mouse genes Ppfia2
  • Rat genes Ppfia2
  • Zfish genes ppfia2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppfia2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PPFIA2	IPI	UniProtKB:O15083	Human	PMID:12923177
Molecular Function	GO:0005515	protein binding	PPFIA2	IPI	UniProtKB:F1M4A4	Human	PMID:30021165
Molecular Function	GO:0005515	protein binding	Ppfia2	IPI	PR:O70589	Mouse	PMID:23791195
Molecular Function	GO:0005515	protein binding	Ppfia2	IPI	PR:O70589	Mouse	PMID:18054859
Molecular Function	GO:0005515	protein binding	Ppfia2	IPI	PR:Q9DBZ9	Mouse	PMID:23791195
Molecular Function	GO:0005515	protein binding	Ppfia2	IPI	PR:Q8BSS9	Mouse	PMID:16186258
Molecular Function	GO:0005515	protein binding	Ppfia2	IPI	PR:Q6PH08	Mouse	PMID:23791195
Molecular Function	GO:0044877	protein-containing complex binding	Ppfia2	IDA		Mouse	PMID:23791195
Molecular Function	GO:0099181	structural constituent of presynapse	Ppfia2	IDA		Rat	PMID:23751498|RGD:13702233
Molecular Function	GO:0099181	structural constituent of presynapse	Ppfia2	IMP		Rat	PMID:23751498|RGD:13702233
Cellular Component	GO:0043197	dendritic spine	PPFIA2	IDA		Human	PMID:30021165
Cellular Component	GO:0070062	extracellular exosome	PPFIA2	HDA		Human	PMID:19056867
Cellular Component	GO:0098978	glutamatergic synapse	Ppfia2	IDA		Mouse	PMID:29439199
Cellular Component	GO:0098978	glutamatergic synapse	Ppfia2	IDA		Rat	PMID:23751498|RGD:13702233
Cellular Component	GO:0098978	glutamatergic synapse	Ppfia2	IMP		Rat	PMID:23751498|RGD:13702233
Cellular Component	GO:0099572	postsynaptic specialization	Ppfia2	IDA		Rat	PMID:11931740|RGD:619588
Cellular Component	GO:0099523	presynaptic cytosol	Ppfia2	IDA		Mouse	PMID:29439199
Cellular Component	GO:0042734	presynaptic membrane	Ppfia2	IDA		Rat	PMID:11931740|RGD:619588
Cellular Component	GO:0045202	synapse	Ppfia2	IDA		Mouse	PMID:16186258
Cellular Component	GO:0045202	synapse	Ppfia2	IDA		Mouse	PMID:21618221
Cellular Component	GO:0008021	synaptic vesicle	Ppfia2	IDA		Rat	PMID:11931740|RGD:619588
Biological Process	GO:0099519	dense core granule cytoskeletal transport	PPFIA2	IMP		Human	PMID:30021165
Biological Process	GO:0060998	regulation of dendritic spine development	PPFIA2	IMP		Human	PMID:30021165
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	PPFIA2	IMP		Human	PMID:30021165
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Ppfia2	IDA		Rat	PMID:23751498|RGD:13702233
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Ppfia2	IMP		Rat	PMID:23751498|RGD:13702233

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern