Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPHLN1
  • Mouse genes Pphln1
  • Rat genes Pphln1
  • Zfish genes pphln1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pphln1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PPHLN1	IPI	UniProtKB:Q2TAC2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPHLN1	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPHLN1	IPI	UniProtKB:Q9BZW7	Human	PMID:25416956
Molecular Function	GO:0003723	RNA binding	PPHLN1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	PPHLN1	HDA		Human	PMID:22681889
Cellular Component	GO:0005829	cytosol	PPHLN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	PPHLN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PPHLN1	IDA		Human	GO_REF:0000052
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	PPHLN1	IDA		Human	PMID:26022416
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	PPHLN1	IDA		Human	PMID:28581500
Biological Process	GO:0090309	positive regulation of DNA methylation-dependent heterochromatin formation	PPHLN1	IDA		Human	PMID:28581500
Biological Process	GO:0097355	protein localization to heterochromatin	PPHLN1	IDA		Human	PMID:28581500

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern