Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPID
  • Mouse genes Ppid
  • Rat genes Ppid,Ppidl1
  • Zfish genes ppid
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppid

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016018	cyclosporin A binding	PPID	IDA		Human	PMID:20676357
Molecular Function	GO:0016018	cyclosporin A binding	Ppid	IDA		Rat	PMID:19832699|RGD:7247324
Molecular Function	GO:0019899	enzyme binding	Ppid	IPI	RGD:1561913	Rat	PMID:9488468|RGD:5688104
Molecular Function	GO:0031072	heat shock protein binding	PPID	IPI	UniProtKB:P07900	Human	PMID:9660753
Molecular Function	GO:0051879	Hsp90 protein binding	PPID	IDA		Human	PMID:12145316
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	PPID	IDA		Human	PMID:11350175
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	PPID	IDA		Human	PMID:20676357
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	Ppid	IDA		Rat	PMID:12077116|RGD:625503
Molecular Function	GO:0005515	protein binding	PPID	IPI	UniProtKB:P12235	Human	PMID:16507998
Molecular Function	GO:0005515	protein binding	PPID	IPI	UniProtKB:P05067:PRO_0000000092	Human	PMID:18806802
Molecular Function	GO:0005515	protein binding	PPID	IPI	UniProtKB:P05067:PRO_0000000093	Human	PMID:18806802
Molecular Function	GO:0005515	protein binding	PPID	IPI	UniProtKB:P12956	Human	PMID:21146485
Molecular Function	GO:0005515	protein binding	PPID	IPI	UniProtKB:P23396	Human	PMID:21146485
Molecular Function	GO:0005515	protein binding	PPID	IPI	UniProtKB:P63244	Human	PMID:21146485
Molecular Function	GO:0005515	protein binding	PPID	IPI	UniProtKB:Q12905	Human	PMID:21146485
Molecular Function	GO:0005515	protein binding	PPID	IPI	UniProtKB:P48047	Human	PMID:30266287
Molecular Function	GO:0005515	protein binding	PPID	IPI	UniProtKB:P01103	Human	PMID:9659917
Molecular Function	GO:0005515	protein binding	Ppid	IPI	RGD:620352	Rat	PMID:12077116|RGD:625503
Molecular Function	GO:0008134	transcription factor binding	PPID	IDA		Human	PMID:9659917
Cellular Component	GO:0005737	cytoplasm	PPID	IDA		Human	PMID:11525244
Cellular Component	GO:0005829	cytosol	PPID	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Ppid	IDA		Rat	PMID:12077116|RGD:625503
Cellular Component	GO:0005730	nucleolus	PPID	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	PPID	IDA		Human	PMID:11525244
Cellular Component	GO:0005654	nucleoplasm	PPID	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PPID	IDA		Human	PMID:11525244
Biological Process	GO:0071492	cellular response to UV-A	PPID	IMP		Human	PMID:23220213
Biological Process	GO:0061077	chaperone-mediated protein folding	PPID	IDA		Human	PMID:11350175
Biological Process	GO:0034389	lipid droplet organization	PPID	IMP		Human	PMID:21711559
Biological Process	GO:0043066	negative regulation of apoptotic process	Ppid	IMP		Rat	PMID:12077116|RGD:625503
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	PPID	IMP		Human	PMID:18708059
Biological Process	GO:0043065	positive regulation of apoptotic process	PPID	IMP		Human	PMID:23220213
Biological Process	GO:0050714	positive regulation of protein secretion	PPID	IMP		Human	PMID:21711559
Biological Process	GO:0045070	positive regulation of viral genome replication	PPID	IMP		Human	PMID:19932913
Biological Process	GO:0000413	protein peptidyl-prolyl isomerization	PPID	IDA		Human	PMID:20676357
Biological Process	GO:0000413	protein peptidyl-prolyl isomerization	Ppid	IDA		Rat	PMID:12077116|RGD:625503
Biological Process	GO:0065003	protein-containing complex assembly	PPID	IDA		Human	PMID:18708059
Biological Process	GO:0051881	regulation of mitochondrial membrane potential	Ppid	IMP		Rat	PMID:12077116|RGD:625503
Biological Process	GO:0006979	response to oxidative stress	Ppid	IMP		Rat	PMID:12077116|RGD:625503

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern