Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ppif

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PPIF
- Mouse genes Ppif
- Rat genes Ppif
- Zfish genes ppifa,ppifb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppif

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016018	cyclosporin A binding	PPIF	IDA		Human	PMID:20676357
Molecular Function	GO:0016018	cyclosporin A binding	Ppif	IDA		Rat	PMID:1599421\|RGD:729430
Molecular Function	GO:0042277	peptide binding	Ppif	IDA		Rat	PMID:15233627\|RGD:2303985
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	PPIF	IDA		Human	PMID:20676357
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	Ppif	IDA		Rat	PMID:15233627\|RGD:2303985
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	Ppif	IDA		Rat	PMID:1599421\|RGD:729430
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:P04637	Human	PMID:22726440
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:Q8N9N5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:Q96DZ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:Q9NYB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:Q9UQ90	Human	PMID:26387735
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:Q9NYB9	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:B3EWG5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:O95070	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:P08247	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:P15941-11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:P43364	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:P53365	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:Q04118	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:Q16563	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:Q6RW13-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:Q9NYB9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:Q9Y680	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPIF	IPI	UniProtKB:P05067:PRO_0000000092	Human	PMID:32825572
Molecular Function	GO:0005515	protein binding	Ppif	IPI	UniProtKB:P01023\|UniProtKB:P42858\|UniProtKB:P50570-2	Mouse	MGI:MGI:6467711\|PMID:32814053
Molecular Function	GO:0005515	protein binding	Ppif	IPI	PR:P02340	Mouse	PMID:22726440
Molecular Function	GO:0005515	protein binding	Ppif	IPI	RGD:620352\|RGD:620353	Rat	PMID:9820802\|RGD:2304024
Cellular Component	GO:0005743	mitochondrial inner membrane	Ppif	IDA		Rat	PMID:9820802\|RGD:2304024
Cellular Component	GO:0005759	mitochondrial matrix	Ppif	IDA		Rat	PMID:1599421\|RGD:729430
Cellular Component	GO:0005757	mitochondrial permeability transition pore complex	PPIF	IDA		Human	PMID:26387735
Cellular Component	GO:0005757	mitochondrial permeability transition pore complex	Ppif	IMP		Mouse	MGI:MGI:6414748\|PMID:31489369
Cellular Component	GO:0005739	mitochondrion	PPIF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Ppif	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Ppif	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Ppif	IDA		Rat	PMID:15233627\|RGD:2303985
Biological Process	GO:0008637	apoptotic mitochondrial changes	Ppif	IGI	MGI:MGI:1315197	Mouse	PMID:18350175
Biological Process	GO:0008637	apoptotic mitochondrial changes	Ppif	IGI	MGI:MGI:1353495	Mouse	PMID:18350175
Biological Process	GO:0071243	cellular response to arsenic-containing substance	Ppif	IMP		Mouse	MGI:MGI:5487522\|PMID:21281446
Biological Process	GO:0071277	cellular response to calcium ion	Ppif	IMP		Mouse	MGI:MGI:3576003\|PMID:15800626
Biological Process	GO:0071277	cellular response to calcium ion	Ppif	IMP		Mouse	MGI:MGI:3575990\|PMID:15800627
Biological Process	GO:0071277	cellular response to calcium ion	Ppif	IMP		Mouse	MGI:MGI:3603054\|PMID:16103352
Biological Process	GO:0070301	cellular response to hydrogen peroxide	PPIF	IMP		Human	PMID:22726440
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Ppif	IMP		Mouse	MGI:MGI:3576003\|PMID:15800626
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Ppif	IMP		Mouse	MGI:MGI:3603054\|PMID:16103352
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Ppif	IMP		Mouse	MGI:MGI:3575990\|PMID:15800627
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Ppif	IMP		Mouse	MGI:MGI:5431269\|PMID:22726440
Biological Process	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	PPIF	IMP		Human	PMID:26387735
Biological Process	GO:0070266	necroptotic process	Ppif	IGI	MGI:MGI:98834	Mouse	PMID:22726440
Biological Process	GO:0043066	negative regulation of apoptotic process	PPIF	IDA		Human	PMID:19228691
Biological Process	GO:0032780	negative regulation of ATP-dependent activity	Ppif	IMP		Mouse	MGI:MGI:5487522\|PMID:21281446
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	PPIF	IMP		Human	PMID:19228691
Biological Process	GO:0090324	negative regulation of oxidative phosphorylation	Ppif	IMP		Mouse	MGI:MGI:5487522\|PMID:21281446
Biological Process	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity	Ppif	IMP		Mouse	MGI:MGI:5487522\|PMID:21281446
Biological Process	GO:0090201	negative regulation of release of cytochrome c from mitochondria	PPIF	IDA		Human	PMID:19228691
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	Ppif	IMP		Mouse	MGI:MGI:3575990\|PMID:15800627
Biological Process	GO:0000413	protein peptidyl-prolyl isomerization	PPIF	IDA		Human	PMID:20676357
Biological Process	GO:0042981	regulation of apoptotic process	Ppif	IDA		Rat	PMID:15233627\|RGD:2303985
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	PPIF	IMP		Human	PMID:26387735
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	Ppif	IMP		Mouse	MGI:MGI:5486541\|PMID:18684715
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	Ppif	IMP		Mouse	MGI:MGI:3603054\|PMID:16103352
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	Ppif	IMP		Mouse	MGI:MGI:6414748\|PMID:31489369
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	Ppif	IGI	MGI:MGI:98834	Mouse	PMID:22726440
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	Ppif	IDA		Rat	PMID:15233627\|RGD:2303985
Biological Process	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	PPIF	IMP		Human	PMID:22726440
Biological Process	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	Ppif	IMP		Mouse	MGI:MGI:3603054\|PMID:16103352
Biological Process	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	Ppif	IMP		Mouse	MGI:MGI:5431269\|PMID:22726440
Biological Process	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	Ppif	IMP		Mouse	MGI:MGI:3576003\|PMID:15800626
Biological Process	GO:0010939	regulation of necrotic cell death	Ppif	IDA		Mouse	MGI:MGI:3575990\|PMID:15800627
Biological Process	GO:0010849	regulation of proton-transporting ATPase activity, rotational mechanism	Ppif	IMP		Mouse	MGI:MGI:5487522\|PMID:21281446
Biological Process	GO:0010849	regulation of proton-transporting ATPase activity, rotational mechanism	Ppif	IMP		Mouse	MGI:MGI:5486536\|PMID:19801635
Biological Process	GO:0002931	response to ischemia	Ppif	IMP		Mouse	MGI:MGI:3576003\|PMID:15800626
Biological Process	GO:0002931	response to ischemia	Ppif	IMP		Mouse	MGI:MGI:3603054\|PMID:16103352
Biological Process	GO:0006979	response to oxidative stress	Ppif	IGI	MGI:MGI:98834	Mouse	PMID:22726440

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.