Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPM1B
  • Mouse genes Ppm1b
  • Rat genes Ppm1b
  • Zfish genes ppm1ba,ppm1bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppm1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PPM1B	IPI	UniProtKB:P05161	Human	PMID:16872604
Molecular Function	GO:0005515	protein binding	PPM1B	IPI	UniProtKB:P32121	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	PPM1B	IPI	UniProtKB:P49407	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	PPM1B	IPI	UniProtKB:O14920	Human	PMID:18930133
Molecular Function	GO:0005515	protein binding	PPM1B	IPI	UniProtKB:P32121	Human	PMID:25241761
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PPM1B	IDA		Human	PMID:20801214
Cellular Component	GO:0005829	cytosol	PPM1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Ppm1b	IDA		Mouse	MGI:MGI:5470043|PMID:23088624
Cellular Component	GO:0016020	membrane	Ppm1b	IDA		Mouse	MGI:MGI:5470043|PMID:23088624
Cellular Component	GO:0005730	nucleolus	PPM1B	IDA		Human	GO_REF:0000052
Biological Process	GO:0006499	N-terminal protein myristoylation	Ppm1b	IDA		Mouse	MGI:MGI:5470043|PMID:23088624
Biological Process	GO:0050687	negative regulation of defense response to virus	PPM1B	IMP		Human	PMID:22750291
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	PPM1B	IMP		Human	PMID:18930133
Biological Process	GO:0032688	negative regulation of interferon-beta production	PPM1B	IMP		Human	PMID:22750291
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	PPM1B	IMP		Human	PMID:18930133
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	ppm1bb	IMP		Zfish	PMID:16751101
Biological Process	GO:0035970	peptidyl-threonine dephosphorylation	PPM1B	IDA		Human	PMID:20801214
Biological Process	GO:0006470	protein dephosphorylation	PPM1B	IMP		Human	PMID:18930133
Biological Process	GO:0006470	protein dephosphorylation	PPM1B	IMP		Human	PMID:22750291
Biological Process	GO:0006470	protein dephosphorylation	Ppm1b	IMP		Mouse	MGI:MGI:5470043|PMID:23088624

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern