Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPM1E
  • Mouse genes Ppm1e
  • Rat genes Ppm1e
  • Zfish genes ppm1e
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppm1e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PPM1E	IPI	UniProtKB:Q14155	Human	PMID:11864573
Molecular Function	GO:0005515	protein binding	PPM1E	IPI	UniProtKB:Q15052	Human	PMID:11864573
Molecular Function	GO:0005515	protein binding	PPM1E	IPI	UniProtKB:P54646	Human	PMID:20801214
Molecular Function	GO:0005515	protein binding	PPM1E	IPI	UniProtKB:Q92845	Human	PMID:24338362
Molecular Function	GO:0005515	protein binding	Ppm1e	IPI	UniProtKB:P04797	Rat	PMID:15680915|RGD:8553307
Molecular Function	GO:0005515	protein binding	Ppm1e	IPI	UniProtKB:P05065	Rat	PMID:15680915|RGD:8553307
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PPM1E	IDA		Human	PMID:20801214
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	Ppm1e	IDA		Rat	PMID:11726284|RGD:8553885
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	Ppm1e	IDA		Rat	PMID:12807427|RGD:1299619
Cellular Component	GO:0005737	cytoplasm	Ppm1e	IDA		Rat	PMID:16269004|RGD:7241143
Cellular Component	GO:0005739	mitochondrion	Ppm1e	IDA		Rat	PMID:16269004|RGD:7241143
Cellular Component	GO:0005730	nucleolus	PPM1E	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PPM1E	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ppm1e	IDA		Rat	PMID:11726284|RGD:8553885
Cellular Component	GO:0005634	nucleus	Ppm1e	IDA		Rat	PMID:12807427|RGD:1299619
Cellular Component	GO:0005634	nucleus	Ppm1e	IDA		Rat	PMID:16269004|RGD:7241143
Cellular Component	GO:0005634	nucleus	ppm1e	IDA		Zfish	PMID:17169323
Cellular Component	GO:0032991	protein-containing complex	PPM1E	IDA		Human	PMID:11864573
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	PPM1E	IDA		Human	PMID:20801214
Biological Process	GO:0016311	dephosphorylation	ppm1e	IDA		Zfish	PMID:17169323
Biological Process	GO:0006469	negative regulation of protein kinase activity	PPM1E	IDA		Human	PMID:11864573
Biological Process	GO:0035970	peptidyl-threonine dephosphorylation	PPM1E	IDA		Human	PMID:20801214
Biological Process	GO:0051496	positive regulation of stress fiber assembly	PPM1E	IDA		Human	PMID:11864573
Biological Process	GO:0006470	protein dephosphorylation	Ppm1e	IMP		Mouse	MGI:MGI:5470043|PMID:23088624

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern