Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPOX
  • Mouse genes Ppox
  • Rat genes Ppox
  • Zfish genes ppox
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppox

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004729	oxygen-dependent protoporphyrinogen oxidase activity	PPOX	IDA		Human	PMID:7713909
Molecular Function	GO:0004729	oxygen-dependent protoporphyrinogen oxidase activity	Ppox	IDA		Mouse	MGI:MGI:3687447|PMID:3346226
Molecular Function	GO:0004729	oxygen-dependent protoporphyrinogen oxidase activity	Ppox	IDA		Rat	PMID:3663105|RGD:1599180
Molecular Function	GO:0005515	protein binding	Ppox	IPI	PR:Q65Z93	Mouse	PMID:34354145
Cellular Component	GO:0005743	mitochondrial inner membrane	Ppox	IDA		Mouse	MGI:MGI:3687447|PMID:3346226
Cellular Component	GO:0005743	mitochondrial inner membrane	Ppox	IDA		Rat	PMID:3996415|RGD:1599183
Cellular Component	GO:0031966	mitochondrial membrane	PPOX	IMP		Human	PMID:7713909
Cellular Component	GO:0005739	mitochondrion	Ppox	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Ppox	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Ppox	IDA		Rat	PMID:3663105|RGD:1599180
Biological Process	GO:0006783	heme biosynthetic process	PPOX	IDA		Human	PMID:7713909
Biological Process	GO:0006783	heme biosynthetic process	Ppox	IDA		Mouse	PMID:3346226
Biological Process	GO:0006783	heme biosynthetic process	Ppox	IDA		Rat	PMID:3955059|RGD:1600961
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	PPOX	IDA		Human	PMID:7713909
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	Ppox	IDA		Rat	PMID:3663105|RGD:1599180
Biological Process	GO:0046501	protoporphyrinogen IX metabolic process	Ppox	IDA		Rat	PMID:3663105|RGD:1599180
Biological Process	GO:0009410	response to xenobiotic stimulus	Ppox	IEP		Rat	PMID:6316951|RGD:4145275

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern