Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ppp1r15a

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PPP1R15A
- Mouse genes Ppp1r15a
- Rat genes Ppp1r15a
- Zfish genes ppp1r15a
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp1r15a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PPP1R15A	IPI	UniProtKB:Q13522	Human	PMID:11564868
Molecular Function	GO:0005515	protein binding	PPP1R15A	IPI	UniProtKB:P62136	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	PPP1R15A	IPI	UniProtKB:P56545	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	PPP1R15A	IPI	UniProtKB:P62136	Human	PMID:26095357
Molecular Function	GO:0005515	protein binding	PPP1R15A	IPI	UniProtKB:P62136	Human	PMID:29109149
Molecular Function	GO:0005515	protein binding	PPP1R15A	IPI	UniProtKB:Q13148	Human	PMID:29109149
Molecular Function	GO:0005515	protein binding	Ppp1r15a	IPI	RGD:620124	Rat	PMID:21925170\|RGD:9999170
Molecular Function	GO:0019901	protein kinase binding	PPP1R15A	IPI	UniProtKB:P07948	Human	PMID:11517336
Molecular Function	GO:0008157	protein phosphatase 1 binding	PPP1R15A	IDA		Human	PMID:11564868
Molecular Function	GO:0008157	protein phosphatase 1 binding	PPP1R15A	IPI	UniProtKB:P62136	Human	PMID:12556489
Molecular Function	GO:0008157	protein phosphatase 1 binding	PPP1R15A	IPI	UniProtKB:P62136	Human	PMID:21518769
Molecular Function	GO:0008157	protein phosphatase 1 binding	Ppp1r15a	IDA		Rat	PMID:17760864\|RGD:9999404
Molecular Function	GO:0019903	protein phosphatase binding	Ppp1r15a	IDA		Mouse	MGI:MGI:5605960\|PMID:11381086
Molecular Function	GO:0019888	protein phosphatase regulator activity	Ppp1r15a	IDA		Mouse	MGI:MGI:5605960\|PMID:11381086
Cellular Component	GO:0005737	cytoplasm	PPP1R15A	IDA		Human	PMID:21518769
Cellular Component	GO:0005737	cytoplasm	Ppp1r15a	IDA		Rat	PMID:15713259\|RGD:9999408
Cellular Component	GO:0005829	cytosol	Ppp1r15a	IDA		Rat	PMID:17760864\|RGD:9999404
Cellular Component	GO:0005783	endoplasmic reticulum	PPP1R15A	IDA		Human	PMID:12556489
Cellular Component	GO:0005783	endoplasmic reticulum	PPP1R15A	IDA		Human	PMID:21518769
Cellular Component	GO:0005794	Golgi apparatus	PPP1R15A	IDA		Human	PMID:21518769
Cellular Component	GO:0016020	membrane	PPP1R15A	IDA		Human	PMID:21518769
Cellular Component	GO:0005739	mitochondrion	PPP1R15A	IDA		Human	PMID:21518769
Cellular Component	GO:0000164	protein phosphatase type 1 complex	PPP1R15A	IDA		Human	PMID:11564868
Cellular Component	GO:0000164	protein phosphatase type 1 complex	PPP1R15A	IDA		Human	PMID:12556489
Biological Process	GO:0007568	aging	Ppp1r15a	IEP		Rat	PMID:17300747\|RGD:9999405
Biological Process	GO:0071236	cellular response to antibiotic	Ppp1r15a	IEP		Rat	PMID:21925170\|RGD:9999170
Biological Process	GO:0072732	cellular response to calcium ion starvation	Ppp1r15a	IEP		Rat	PMID:9878749\|RGD:9999163
Biological Process	GO:0071322	cellular response to carbohydrate stimulus	Ppp1r15a	IEP		Rat	PMID:24291486\|RGD:9999414
Biological Process	GO:1904310	cellular response to cordycepin	Ppp1r15a	IEP		Rat	PMID:21597460\|RGD:10045896
Biological Process	GO:1904308	cellular response to desipramine	Ppp1r15a	IEP		Rat	PMID:20549303\|RGD:9999406
Biological Process	GO:1904312	cellular response to gold(3+)	Ppp1r15a	IEP		Rat	PMID:16206274\|RGD:9999403
Biological Process	GO:1904314	cellular response to methamphetamine hydrochloride	Ppp1r15a	IEP		Rat	PMID:22174933\|RGD:9999411
Biological Process	GO:0072703	cellular response to methyl methanesulfonate	Ppp1r15a	IEP		Rat	PMID:9811446\|RGD:9999409
Biological Process	GO:0071407	cellular response to organic cyclic compound	Ppp1r15a	IEP		Rat	PMID:9878749\|RGD:9999163
Biological Process	GO:0090650	cellular response to oxygen-glucose deprivation	Ppp1r15a	IEP		Rat	PMID:21525936\|RGD:10054236
Biological Process	GO:0034644	cellular response to UV	Ppp1r15a	IEP		Rat	PMID:9811446\|RGD:9999409
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Ppp1r15a	IEP		Rat	PMID:23274394\|RGD:9999168
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	Ppp1r15a	IMP	MGI:MGI:2652765	Mouse	PMID:15601821
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	Ppp1r15a	IEP		Rat	PMID:18266951\|RGD:9999413
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	Ppp1r15a	IEP		Rat	PMID:22154936\|RGD:9999171
Biological Process	GO:0008285	negative regulation of cell population proliferation	Ppp1r15a	IDA		Rat	PMID:12813455\|RGD:9854704
Biological Process	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	Ppp1r15a	IDA		Mouse	MGI:MGI:5613475\|PMID:16835242
Biological Process	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	Ppp1r15a	IMP		Rat	PMID:21925170\|RGD:9999170
Biological Process	GO:0032515	negative regulation of phosphoprotein phosphatase activity	PPP1R15A	IDA		Human	PMID:11564868
Biological Process	GO:0035308	negative regulation of protein dephosphorylation	PPP1R15A	IDA		Human	PMID:11564868
Biological Process	GO:0010955	negative regulation of protein processing	Ppp1r15a	IMP		Rat	PMID:21925170\|RGD:9999170
Biological Process	GO:1903573	negative regulation of response to endoplasmic reticulum stress	Ppp1r15a	IDA		Mouse	MGI:MGI:5605960\|PMID:11381086
Biological Process	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	Ppp1r15a	IDA		Mouse	MGI:MGI:5605960\|PMID:11381086
Biological Process	GO:0070262	peptidyl-serine dephosphorylation	Ppp1r15a	IDA		Mouse	MGI:MGI:5613475\|PMID:16835242
Biological Process	GO:0043065	positive regulation of apoptotic process	Ppp1r15a	IDA		Rat	PMID:12813455\|RGD:9854704
Biological Process	GO:0043065	positive regulation of apoptotic process	Ppp1r15a	IMP		Rat	PMID:16206274\|RGD:9999403
Biological Process	GO:1903917	positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation	PPP1R15A	IDA		Human	PMID:21518769
Biological Process	GO:0010628	positive regulation of gene expression	Ppp1r15a	IDA		Mouse	MGI:MGI:5751679\|PMID:14635196
Biological Process	GO:1902310	positive regulation of peptidyl-serine dephosphorylation	PPP1R15A	IDA		Human	PMID:11564868
Biological Process	GO:1902310	positive regulation of peptidyl-serine dephosphorylation	PPP1R15A	IDA		Human	PMID:12556489
Biological Process	GO:1902310	positive regulation of peptidyl-serine dephosphorylation	PPP1R15A	IDA		Human	PMID:21518769
Biological Process	GO:1902310	positive regulation of peptidyl-serine dephosphorylation	Ppp1r15a	IDA		Mouse	MGI:MGI:5605960\|PMID:11381086
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	Ppp1r15a	IDA		Mouse	MGI:MGI:5751679\|PMID:14635196
Biological Process	GO:0032516	positive regulation of phosphoprotein phosphatase activity	PPP1R15A	IDA		Human	PMID:11564868
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Ppp1r15a	IDA		Rat	PMID:15674324\|RGD:9854706
Biological Process	GO:0045943	positive regulation of transcription by RNA polymerase I	Ppp1r15a	IDA		Mouse	MGI:MGI:5751679\|PMID:14635196
Biological Process	GO:0070972	protein localization to endoplasmic reticulum	PPP1R15A	IMP		Human	PMID:12556489
Biological Process	GO:0045765	regulation of angiogenesis	Ppp1r15a	IMP		Rat	PMID:10611347\|RGD:9999146
Biological Process	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	Ppp1r15a	IDA		Mouse	MGI:MGI:5605960\|PMID:11381086
Biological Process	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation	PPP1R15A	IDA		Human	PMID:12556489
Biological Process	GO:0042220	response to cocaine	Ppp1r15a	IEP		Rat	PMID:23644055\|RGD:9999166
Biological Process	GO:0034976	response to endoplasmic reticulum stress	PPP1R15A	IDA		Human	PMID:12556489
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Ppp1r15a	IMP		Mouse	MGI:MGI:3525819\|PMID:15601821
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Ppp1r15a	IEP		Rat	PMID:11389688\|RGD:9999412
Biological Process	GO:0090648	response to environmental enrichment	Ppp1r15a	IEP		Rat	PMID:23644055\|RGD:9999166
Biological Process	GO:0035902	response to immobilization stress	Ppp1r15a	IEP		Rat	PMID:23644055\|RGD:9999166
Biological Process	GO:0014070	response to organic cyclic compound	Ppp1r15a	IEP		Rat	PMID:19564919\|RGD:9999415

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.