Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP1R1B
  • Mouse genes Ppp1r1b
  • Rat genes Ppp1r1b
  • Zfish genes ppp1r1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp1r1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031748	D1 dopamine receptor binding	Ppp1r1b	IPI	RGD:2518	Rat	PMID:19465068|RGD:2311555
Molecular Function	GO:0031749	D2 dopamine receptor binding	Ppp1r1b	IPI	RGD:2520	Rat	PMID:19465068|RGD:2311555
Molecular Function	GO:0031750	D3 dopamine receptor binding	Ppp1r1b	IPI	RGD:2521	Rat	PMID:19465068|RGD:2311555
Molecular Function	GO:0031751	D4 dopamine receptor binding	Ppp1r1b	IPI	RGD:2522	Rat	PMID:19465068|RGD:2311555
Molecular Function	GO:0031752	D5 dopamine receptor binding	Ppp1r1b	IPI	RGD:2523	Rat	PMID:19465068|RGD:2311555
Molecular Function	GO:0005515	protein binding	PPP1R1B	IPI	UniProtKB:Q12800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPP1R1B	IPI	UniProtKB:Q8WZ60	Human	PMID:25416956
Molecular Function	GO:0004864	protein phosphatase inhibitor activity	PPP1R1B	IDA		Human	PMID:10807923
Cellular Component	GO:0005737	cytoplasm	Ppp1r1b	IDA		Mouse	PMID:18496528
Cellular Component	GO:0044327	dendritic spine head	Ppp1r1b	IDA		Rat	PMID:24058659|RGD:13515074
Cellular Component	GO:0044326	dendritic spine neck	Ppp1r1b	IDA		Rat	PMID:24058659|RGD:13515074
Cellular Component	GO:0098978	glutamatergic synapse	Ppp1r1b	IDA		Rat	PMID:24058659|RGD:13515074
Cellular Component	GO:0043025	neuronal cell body	Ppp1r1b	IDA		Mouse	PMID:18923023
Cellular Component	GO:0005634	nucleus	Ppp1r1b	IDA		Mouse	PMID:18496528
Cellular Component	GO:0005634	nucleus	Ppp1r1b	IDA		Rat	PMID:20074680|RGD:13515079
Cellular Component	GO:0098794	postsynapse	Ppp1r1b	IDA		Rat	PMID:24058659|RGD:13515074
Biological Process	GO:0048148	behavioral response to cocaine	Ppp1r1b	IMP	MGI:MGI:3799291	Mouse	PMID:18496528
Biological Process	GO:0071314	cellular response to cocaine	Ppp1r1b	IMP	MGI:MGI:3799291	Mouse	PMID:18496528
Biological Process	GO:0006351	DNA-templated transcription	Ppp1r1b	IMP		Mouse	PMID:10854268
Biological Process	GO:0035556	intracellular signal transduction	Ppp1r1b	IDA		Rat	PMID:12466426|RGD:724660
Biological Process	GO:0007626	locomotory behavior	Ppp1r1b	IMP	MGI:MGI:3799291	Mouse	PMID:18496528
Biological Process	GO:0007626	locomotory behavior	Ppp1r1b	IDA		Rat	PMID:22952905|RGD:10059420
Biological Process	GO:0007613	memory	Ppp1r1b	IMP		Rat	PMID:16687181|RGD:1582430
Biological Process	GO:0007621	negative regulation of female receptivity	Ppp1r1b	IMP		Mouse	PMID:10669419
Biological Process	GO:0007621	negative regulation of female receptivity	Ppp1r1b	IDA		Mouse	PMID:10669419
Biological Process	GO:0032515	negative regulation of phosphoprotein phosphatase activity	PPP1R1B	IDA		Human	PMID:10807923
Biological Process	GO:0001975	response to amphetamine	Ppp1r1b	IGI	MGI:MGI:97523	Mouse	PMID:17010100
Biological Process	GO:0001975	response to amphetamine	Ppp1r1b	IMP	MGI:MGI:3799291	Mouse	PMID:18496528
Biological Process	GO:0042220	response to cocaine	Ppp1r1b	IDA		Rat	PMID:26142455|RGD:13514094
Biological Process	GO:0043278	response to morphine	Ppp1r1b	IMP	MGI:MGI:3799291	Mouse	PMID:18496528
Biological Process	GO:0035094	response to nicotine	Ppp1r1b	IDA		Rat	PMID:22952905|RGD:10059420
Biological Process	GO:0008542	visual learning	Ppp1r1b	IGI	MGI:MGI:97523	Mouse	PMID:17010100

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern