Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP2R2A
  • Mouse genes Ppp2r2a
  • Rat genes Ppp2r2a
  • Zfish genes ppp2r2aa,ppp2r2ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp2r2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:15761952
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P04637	Human	PMID:17245430
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:17245430
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:17529992
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:17540176
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30154	Human	PMID:17540176
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:17632056
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:18782753
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:19156129
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:19293187
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:19915589
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P53355	Human	PMID:20220139
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:20711181
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:Q00613	Human	PMID:25816751
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:Q5VY09	Human	PMID:25816751
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30154	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:Q5S007	Human	PMID:26894577
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:Q96E09	Human	PMID:27588481
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30154	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:Q9Y4C4	Human	PMID:28609714
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P67775	Human	PMID:30595372
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:Q91X84	Human	PMID:30611118
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:Q5S007	Human	PMID:31046837
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P53355	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:Q15843	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:Q8NE08	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:Q9NZR2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:Q96E09	Human	PMID:33108758
Molecular Function	GO:0005515	protein binding	PPP2R2A	IPI	UniProtKB:P30153	Human	PMID:9847399
Molecular Function	GO:0005515	protein binding	Ppp2r2a	IPI	UniProtKB:E1ARS9	Rat	PMID:23530045|RGD:8693581
Molecular Function	GO:0051721	protein phosphatase 2A binding	Ppp2r2a	IPI	RGD:3380	Rat	PMID:11032905|RGD:8693395
Molecular Function	GO:0019888	protein phosphatase regulator activity	PPP2R2A	IDA		Human	PMID:1849734
Molecular Function	GO:0044877	protein-containing complex binding	Ppp2r2a	IPI	RGD:3380|RGD:69329	Rat	PMID:11032905|RGD:8693395
Molecular Function	GO:0048156	tau protein binding	Ppp2r2a	IPI	RGD:69329	Rat	PMID:11032905|RGD:8693395
Cellular Component	GO:0098978	glutamatergic synapse	Ppp2r2a	IDA		Mouse	PMID:24413018
Cellular Component	GO:0098978	glutamatergic synapse	Ppp2r2a	EXP		Mouse	PMID:24413018
Cellular Component	GO:0000159	protein phosphatase type 2A complex	PPP2R2A	IDA		Human	PMID:17245430
Cellular Component	GO:0000159	protein phosphatase type 2A complex	PPP2R2A	IDA		Human	PMID:1849734
Cellular Component	GO:0045202	synapse	Ppp2r2a	EXP		Mouse	PMID:24413018
Cellular Component	GO:0045202	synapse	Ppp2r2a	IDA		Mouse	PMID:24413018
Biological Process	GO:0072554	blood vessel lumenization	ppp2r2ab	IGI	ZFIN:ZDB-MRPHLNO-131108-3,ZFIN:ZDB-MRPHLNO-131108-4	Zfish	PMID:23955003
Biological Process	GO:0072554	blood vessel lumenization	ppp2r2aa	IGI	ZFIN:ZDB-MRPHLNO-131108-3,ZFIN:ZDB-MRPHLNO-131108-4	Zfish	PMID:23955003
Biological Process	GO:0006470	protein dephosphorylation	PPP2R2A	IDA		Human	PMID:1849734
Biological Process	GO:0006470	protein dephosphorylation	PPP2R2A	IMP		Human	PMID:33108758
Biological Process	GO:0043278	response to morphine	Ppp2r2a	IMP		Mouse	PMID:16102737

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern