Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP2R2B
  • Mouse genes Ppp2r2b
  • Rat genes Ppp2r2b
  • Zfish genes ppp2r2ba,ppp2r2bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp2r2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PPP2R2B	IPI	UniProtKB:P30153	Human	PMID:17274953
Molecular Function	GO:0005515	protein binding	PPP2R2B	IPI	UniProtKB:P30153	Human	PMID:19156129
Molecular Function	GO:0005515	protein binding	PPP2R2B	IPI	UniProtKB:O15530	Human	PMID:21075311
Molecular Function	GO:0005515	protein binding	PPP2R2B	IPI	UniProtKB:P23443	Human	PMID:21075311
Molecular Function	GO:0005515	protein binding	PPP2R2B	IPI	UniProtKB:P30153	Human	PMID:21075311
Molecular Function	GO:0005515	protein binding	PPP2R2B	IPI	UniProtKB:Q00613	Human	PMID:25816751
Molecular Function	GO:0005515	protein binding	PPP2R2B	IPI	UniProtKB:Q5VY09	Human	PMID:25816751
Molecular Function	GO:0005515	protein binding	PPP2R2B	IPI	UniProtKB:P30153	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP2R2B	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ppp2r2b	IPI	UniProtKB:Q75Q41	Rat	PMID:15923182|RGD:8554174
Molecular Function	GO:0044877	protein-containing complex binding	Ppp2r2b	IDA		Rat	PMID:12716901|RGD:2314541
Cellular Component	GO:0005737	cytoplasm	Ppp2r2b	IDA		Rat	PMID:12716901|RGD:2314541
Cellular Component	GO:0005737	cytoplasm	Ppp2r2b	IDA		Rat	PMID:18940801|RGD:2314538
Cellular Component	GO:0005856	cytoskeleton	Ppp2r2b	IDA		Rat	PMID:9514514|RGD:2314544
Cellular Component	GO:0005829	cytosol	Ppp2r2b	IDA		Rat	PMID:9514514|RGD:2314544
Cellular Component	GO:0016020	membrane	Ppp2r2b	IDA		Rat	PMID:9514514|RGD:2314544
Cellular Component	GO:0005741	mitochondrial outer membrane	Ppp2r2b	IDA		Rat	PMID:15923182|RGD:8554174
Cellular Component	GO:0005739	mitochondrion	Ppp2r2b	IDA		Rat	PMID:12716901|RGD:2314541
Cellular Component	GO:0005739	mitochondrion	Ppp2r2b	IDA		Rat	PMID:18940801|RGD:2314538
Cellular Component	GO:0000159	protein phosphatase type 2A complex	Ppp2r2b	IDA		Rat	PMID:12716901|RGD:2314541
Biological Process	GO:0007420	brain development	Ppp2r2b	IEP		Rat	PMID:12716901|RGD:2314541
Biological Process	GO:0000266	mitochondrial fission	Ppp2r2b	IDA		Rat	PMID:18940801|RGD:2314538
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	Ppp2r2b	IMP		Rat	PMID:18940801|RGD:2314538
Biological Process	GO:0030182	neuron differentiation	Ppp2r2b	IEP		Rat	PMID:12716901|RGD:2314541
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Ppp2r2b	IDA		Rat	PMID:12716901|RGD:2314541
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Ppp2r2b	IDA		Rat	PMID:18940801|RGD:2314538
Biological Process	GO:0006626	protein targeting to mitochondrion	Ppp2r2b	IMP		Rat	PMID:12716901|RGD:2314541
Biological Process	GO:0043666	regulation of phosphoprotein phosphatase activity	Ppp2r2b	IDA		Rat	PMID:12716901|RGD:2314541
Biological Process	GO:0007286	spermatid development	Ppp2r2b	IEP		Rat	PMID:8389301|RGD:633587

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern