Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP2R5A
  • Mouse genes Ppp2r5a
  • Rat genes Ppp2r5a
  • Zfish genes ppp2r5a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp2r5a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019900	kinase binding	PPP2R5A	IPI	UniProtKB:Q9NYA1	Human	PMID:21075214
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	PPP2R5A	IDA		Human	PMID:24157919
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:O96017	Human	PMID:15380617
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:Q9BVP2	Human	PMID:16097049
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:Q5FBB7	Human	PMID:16541025
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P30153	Human	PMID:17245430
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P30154	Human	PMID:17540176
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P30153	Human	PMID:18782753
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P30154	Human	PMID:18782753
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P67775	Human	PMID:18782753
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:Q86YF9	Human	PMID:21878643
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:Q96IK1	Human	PMID:24157919
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P30153	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P67775	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P67775	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P30153	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P67775	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P00540	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P67775	Human	PMID:30595372
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:A6NGS2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P00540	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P45379-11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:Q13136	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:Q86YF9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:Q8N6Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:Q9H246	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:Q9NUL5-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:Q9Y2T1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P00540	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P67775	Human	PMID:7592815
Molecular Function	GO:0005515	protein binding	PPP2R5A	IPI	UniProtKB:P30153	Human	PMID:9847399
Molecular Function	GO:0005515	protein binding	Ppp2r5a	IPI	PR:Q8C8R3	Mouse	PMID:17416611
Cellular Component	GO:0005813	centrosome	PPP2R5A	IDA		Human	PMID:24157919
Cellular Component	GO:0005737	cytoplasm	PPP2R5A	IDA		Human	PMID:21075214
Cellular Component	GO:0005829	cytosol	PPP2R5A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031430	M band	Ppp2r5a	IDA		Mouse	MGI:MGI:3822951|PMID:18782775
Cellular Component	GO:0031430	M band	Ppp2r5a	IDA		Mouse	PMID:17416611
Cellular Component	GO:0005886	plasma membrane	PPP2R5A	IDA		Human	PMID:15569306
Cellular Component	GO:0000159	protein phosphatase type 2A complex	PPP2R5A	IDA		Human	PMID:17245430
Cellular Component	GO:0030018	Z disc	PPP2R5A	IDA		Human	PMID:19131648
Cellular Component	GO:0030018	Z disc	Ppp2r5a	IDA		Mouse	PMID:17416611
Biological Process	GO:0090219	negative regulation of lipid kinase activity	PPP2R5A	IMP		Human	PMID:21075214
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	PPP2R5A	IMP		Human	PMID:21075214
Biological Process	GO:0035307	positive regulation of protein dephosphorylation	PPP2R5A	IMP		Human	PMID:21075214
Biological Process	GO:0006470	protein dephosphorylation	PPP2R5A	IDA		Human	PMID:24157919

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern