Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP4C
  • Mouse genes Ppp4c
  • Rat genes Ppp4c
  • Zfish genes ppp4ca,ppp4cb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp4c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005521	lamin binding	Ppp4c	IDA		Rat	PMID:16830232|RGD:8693738
Molecular Function	GO:0016791	phosphatase activity	Ppp4c	IDA		Rat	PMID:16830232|RGD:8693738
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q9P1A2	Human	PMID:10026142
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:O15379	Human	PMID:15805470
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:O75663	Human	PMID:16085932
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P78318	Human	PMID:16085932
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q8TF05	Human	PMID:16085932
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q9NY27	Human	PMID:16085932
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P78318	Human	PMID:16769727
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:O75663	Human	PMID:17384681
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:O75663	Human	PMID:18614045
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P78318	Human	PMID:18614045
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q8TF05	Human	PMID:18614045
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q9NY27	Human	PMID:18614045
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P30153	Human	PMID:18715871
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P78318	Human	PMID:18715871
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q6NUP7	Human	PMID:18715871
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q8TF05	Human	PMID:18715871
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q9NY27	Human	PMID:18715871
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P30153	Human	PMID:19156129
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P78318	Human	PMID:19156129
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q9NY27	Human	PMID:19156129
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P78318	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q8TF05	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q9NY27	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:O75663	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P30153	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P78318	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q6NUP7	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q8TF05	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q9NY27	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P30153	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q9NY27	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q6NUP7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:Q9NY27	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:O95872	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P78318	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP4C	IPI	UniProtKB:P78318	Human	PMID:9647778
Molecular Function	GO:0005515	protein binding	Ppp4c	IPI	PR:Q6P2K6	Mouse	PMID:20876121
Molecular Function	GO:0005515	protein binding	Ppp4c	IPI	PR:Q922R5	Mouse	PMID:20876121
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PPP4C	IDA		Human	PMID:20154705
Molecular Function	GO:0044877	protein-containing complex binding	Ppp4c	IDA		Rat	PMID:10769191|RGD:8693736
Cellular Component	GO:0000785	chromatin	PPP4C	IDA		Human	PMID:18614045
Cellular Component	GO:0005737	cytoplasm	Ppp4c	IDA		Mouse	PMID:20876121
Cellular Component	GO:0005829	cytosol	PPP4C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PPP4C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ppp4c	IDA		Mouse	PMID:20876121
Cellular Component	GO:0005634	nucleus	Ppp4c	IDA		Rat	PMID:16830232|RGD:8693738
Cellular Component	GO:0005886	plasma membrane	PPP4C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030289	protein phosphatase 4 complex	PPP4C	IPI		Human	PMID:18614045
Cellular Component	GO:0030289	protein phosphatase 4 complex	Ppp4c	IDA		Mouse	PMID:20876121
Biological Process	GO:0001525	angiogenesis	ppp4ca	IMP	ZFIN:ZDB-MRPHLNO-090616-18,ZFIN:ZDB-MRPHLNO-090616-19	Zfish	PMID:19389629
Biological Process	GO:0001525	angiogenesis	ppp4ca	IMP	ZFIN:ZDB-MRPHLNO-090616-19	Zfish	PMID:19389629
Biological Process	GO:0001525	angiogenesis	ppp4ca	IMP	ZFIN:ZDB-MRPHLNO-090616-18	Zfish	PMID:19389629
Biological Process	GO:0007420	brain development	ppp4ca	IMP	ZFIN:ZDB-MRPHLNO-121207-19	Zfish	PMID:22566537
Biological Process	GO:0071347	cellular response to interleukin-1	Ppp4c	IEP		Rat	PMID:16830232|RGD:8693738
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	ppp4ca	IMP	ZFIN:ZDB-MRPHLNO-121207-19	Zfish	PMID:22566537
Biological Process	GO:0016311	dephosphorylation	Ppp4c	IDA		Rat	PMID:16830232|RGD:8693738
Biological Process	GO:0048264	determination of ventral identity	ppp4ca	IMP	ZFIN:ZDB-MRPHLNO-120606-1	Zfish	PMID:22595677
Biological Process	GO:0048264	determination of ventral identity	ppp4ca	IMP	ZFIN:ZDB-MRPHLNO-120606-2	Zfish	PMID:22595677
Biological Process	GO:0048264	determination of ventral identity	ppp4cb	IMP	ZFIN:ZDB-MRPHLNO-120606-4	Zfish	PMID:22595677
Biological Process	GO:0048264	determination of ventral identity	ppp4cb	IMP	ZFIN:ZDB-MRPHLNO-120606-3	Zfish	PMID:22595677
Biological Process	GO:0009953	dorsal/ventral pattern formation	ppp4ca	IMP	ZFIN:ZDB-MRPHLNO-120606-2	Zfish	PMID:22595677
Biological Process	GO:0009953	dorsal/ventral pattern formation	ppp4ca	IMP	ZFIN:ZDB-MRPHLNO-120606-1	Zfish	PMID:22595677
Biological Process	GO:0009953	dorsal/ventral pattern formation	ppp4cb	IMP	ZFIN:ZDB-MRPHLNO-120606-3	Zfish	PMID:22595677
Biological Process	GO:0009953	dorsal/ventral pattern formation	ppp4cb	IGI	ZFIN:ZDB-MRPHLNO-041116-3,ZFIN:ZDB-MRPHLNO-120606-3	Zfish	PMID:22595677
Biological Process	GO:0009953	dorsal/ventral pattern formation	ppp4cb	IGI	ZFIN:ZDB-MRPHLNO-080825-1,ZFIN:ZDB-MRPHLNO-120606-3	Zfish	PMID:22595677
Biological Process	GO:0009953	dorsal/ventral pattern formation	ppp4cb	IMP	ZFIN:ZDB-MRPHLNO-120606-4	Zfish	PMID:22595677
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	ppp4cb	IMP	ZFIN:ZDB-MRPHLNO-120606-3	Zfish	PMID:22595677
Biological Process	GO:2000779	regulation of double-strand break repair	PPP4C	IMP		Human	PMID:18614045
Biological Process	GO:0010569	regulation of double-strand break repair via homologous recombination	PPP4C	IMP		Human	PMID:20154705

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern