Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP4R2
  • Mouse genes Ppp4r2
  • Rat genes Ppp4r2
  • Zfish genes ppp4r2a,ppp4r2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp4r2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PPP4R2	IPI	UniProtKB:P60510	Human	PMID:16085932
Molecular Function	GO:0005515	protein binding	PPP4R2	IPI	UniProtKB:P60510	Human	PMID:18614045
Molecular Function	GO:0005515	protein binding	PPP4R2	IPI	UniProtKB:P60510	Human	PMID:18715871
Molecular Function	GO:0005515	protein binding	PPP4R2	IPI	UniProtKB:P60510	Human	PMID:19156129
Molecular Function	GO:0005515	protein binding	PPP4R2	IPI	UniProtKB:P15927	Human	PMID:20154705
Molecular Function	GO:0005515	protein binding	PPP4R2	IPI	UniProtKB:P60510	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP4R2	IPI	UniProtKB:P60510	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PPP4R2	IPI	UniProtKB:P60510	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP4R2	IPI	UniProtKB:P60510	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Ppp4r2	IPI	PR:Q922R5	Mouse	PMID:20876121
Molecular Function	GO:0005515	protein binding	Ppp4r2	IPI	PR:Q6P2K6	Mouse	PMID:20876121
Molecular Function	GO:0019888	protein phosphatase regulator activity	PPP4R2	IMP		Human	PMID:20154705
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	PPP4R2	IMP		Human	PMID:20154705
Cellular Component	GO:0000785	chromatin	PPP4R2	IDA		Human	PMID:18614045
Cellular Component	GO:0005737	cytoplasm	Ppp4r2	IDA		Mouse	PMID:20876121
Cellular Component	GO:0005654	nucleoplasm	PPP4R2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PPP4R2	IDA		Human	PMID:20154705
Cellular Component	GO:0005634	nucleus	Ppp4r2	IDA		Mouse	PMID:20876121
Cellular Component	GO:0030289	protein phosphatase 4 complex	PPP4R2	IPI		Human	PMID:18614045
Cellular Component	GO:0030289	protein phosphatase 4 complex	PPP4R2	IDA		Human	PMID:20154705
Cellular Component	GO:0030289	protein phosphatase 4 complex	Ppp4r2	IDA		Mouse	PMID:20876121
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Ppp4r2	IMP		Mouse	PMID:24029230
Biological Process	GO:2000779	regulation of double-strand break repair	PPP4R2	IMP		Human	PMID:18614045
Biological Process	GO:0010569	regulation of double-strand break repair via homologous recombination	PPP4R2	IMP		Human	PMID:20154705

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern