Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP5C
  • Mouse genes Ppp5c
  • Rat genes Ppp5c
  • Zfish genes ppp5c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp5c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043531	ADP binding	PPP5C	IDA		Human	PMID:23184943
Molecular Function	GO:0005524	ATP binding	PPP5C	IDA		Human	PMID:23184943
Molecular Function	GO:0001965	G-protein alpha-subunit binding	Ppp5c	IDA		Rat	PMID:12176367|RGD:8693757
Molecular Function	GO:0031072	heat shock protein binding	Ppp5c	IPI	RGD:631409	Rat	PMID:8943293|RGD:8694070
Molecular Function	GO:0051879	Hsp90 protein binding	PPP5C	IPI	UniProtKB:P07900	Human	PMID:15713458
Molecular Function	GO:0051879	Hsp90 protein binding	PPP5C	IPI	UniProtKB:P08238	Human	PMID:15713458
Molecular Function	GO:0042802	identical protein binding	PPP5C	IPI	UniProtKB:P53041	Human	PMID:21360678
Molecular Function	GO:0008017	microtubule binding	Ppp5c	IDA		Rat	PMID:14690518|RGD:8694075
Molecular Function	GO:0060090	molecular adaptor activity	PPP5C	EXP		Human	PMID:15713458
Molecular Function	GO:0016791	phosphatase activity	PPP5C	IDA		Human	PMID:15546861
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	Ppp5c	IMP		Mouse	PMID:16102737
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	Ppp5c	IMP		Rat	PMID:8077208|RGD:68293
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	Ppp5c	IDA		Rat	PMID:8602837|RGD:8693754
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	Ppp5c	IDA		Rat	PMID:9383998|RGD:8554304
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P30153	Human	PMID:11504734
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P03372	Human	PMID:14764652
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q92731	Human	PMID:14764652
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P08238	Human	PMID:16531226
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q49AN0	Human	PMID:16790549
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P07900	Human	PMID:19875381
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P07900	Human	PMID:21360678
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P08238	Human	PMID:21360678
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P31948	Human	PMID:21360678
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q16543	Human	PMID:21360678
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P08238	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q16543	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P07900	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P08238	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P07900	Human	PMID:27353360
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q8NFG4	Human	PMID:27353360
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P07900	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P08238	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P07900	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P08238	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P31948	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:P50750	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q16543	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q5SY16	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q9H9G7	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q9UL18	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q8TF40	Human	PMID:30699359
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q16526	Human	PMID:9383998
Molecular Function	GO:0005515	protein binding	PPP5C	IPI	UniProtKB:Q49AN0	Human	PMID:9383998
Molecular Function	GO:0005515	protein binding	Ppp5c	IPI	UniProtKB:Q99829	Mouse	MGI:MGI:5294308|PMID:12522145
Molecular Function	GO:0005515	protein binding	Ppp5c	IPI	PR:P06537	Mouse	PMID:12885400
Molecular Function	GO:0005515	protein binding	Ppp5c	IPI	RGD:1306565	Rat	PMID:12786973|RGD:2298728
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PPP5C	IDA		Human	PMID:30699359
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	Ppp5c	IDA		Rat	PMID:15546861|RGD:13507298
Molecular Function	GO:0044877	protein-containing complex binding	Ppp5c	IPI	RGD:1306431|RGD:61998	Rat	PMID:12786973|RGD:2298728
Molecular Function	GO:0044877	protein-containing complex binding	Ppp5c	IDA		Rat	PMID:2829978|RGD:8693749
Molecular Function	GO:0003723	RNA binding	Ppp5c	IDA		Mouse	PMID:21936910
Cellular Component	GO:0071944	cell periphery	Ppp5c	IDA		Rat	PMID:12176367|RGD:8693757
Cellular Component	GO:0005737	cytoplasm	Ppp5c	IDA		Rat	PMID:12786973|RGD:2298728
Cellular Component	GO:0005829	cytosol	PPP5C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Ppp5c	IDA		Mouse	PMID:12885400
Cellular Component	GO:0005829	cytosol	Ppp5c	IDA		Rat	PMID:2829978|RGD:8693749
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PPP5C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043005	neuron projection	Ppp5c	IDA		Rat	PMID:12786973|RGD:2298728
Cellular Component	GO:0043025	neuronal cell body	Ppp5c	IDA		Rat	PMID:12786973|RGD:2298728
Cellular Component	GO:0005634	nucleus	Ppp5c	IDA		Rat	PMID:12786973|RGD:2298728
Cellular Component	GO:0043204	perikaryon	Ppp5c	IDA		Rat	PMID:16899232|RGD:8694073
Cellular Component	GO:0101031	protein folding chaperone complex	PPP5C	IDA		Human	PMID:29127155
Cellular Component	GO:0032991	protein-containing complex	PPP5C	IDA		Human	PMID:23184943
Cellular Component	GO:1990635	proximal dendrite	Ppp5c	IDA		Rat	PMID:16899232|RGD:8694073
Biological Process	GO:0071276	cellular response to cadmium ion	Ppp5c	IEP		Rat	PMID:18703135|RGD:8694082
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Ppp5c	IEP		Rat	PMID:19038359|RGD:8694078
Biological Process	GO:0043066	negative regulation of apoptotic process	Ppp5c	IMP		Rat	PMID:19038359|RGD:8694078
Biological Process	GO:1901215	negative regulation of neuron death	Ppp5c	IMP		Rat	PMID:19686245|RGD:8693743
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Ppp5c	IMP		Rat	PMID:19686245|RGD:8693743
Biological Process	GO:0070262	peptidyl-serine dephosphorylation	PPP5C	IDA		Human	PMID:30699359
Biological Process	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway	Ppp5c	IMP		Rat	PMID:8943293|RGD:8694070
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	PPP5C	HMP		Human	PMID:12761501
Biological Process	GO:0006470	protein dephosphorylation	Ppp5c	IMP		Rat	PMID:16892053|RGD:8694079
Biological Process	GO:0006470	protein dephosphorylation	Ppp5c	IDA		Rat	PMID:8077208|RGD:68293
Biological Process	GO:1904550	response to arachidonic acid	Ppp5c	IDA		Rat	PMID:15546861|RGD:13507298
Biological Process	GO:0010288	response to lead ion	Ppp5c	IDA		Rat	PMID:22387731|RGD:13506262
Biological Process	GO:0010288	response to lead ion	Ppp5c	IEP		Rat	PMID:23134599|RGD:8694077
Biological Process	GO:0043278	response to morphine	Ppp5c	IMP		Mouse	PMID:16102737

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern