Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP6C
  • Mouse genes Ppp6c
  • Rat genes Ppp6c
  • Zfish genes ppp6c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp6c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004857	enzyme inhibitor activity	PPP6C	IDA		Human	PMID:32474700
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O75663	Human	PMID:16085932
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:P78318	Human	PMID:16085932
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O75170	Human	PMID:16769727
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:Q9UPN7	Human	PMID:16769727
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O43318	Human	PMID:17079228
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O75663	Human	PMID:17384681
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O15084	Human	PMID:18186651
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O75170	Human	PMID:18186651
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:P78318	Human	PMID:18186651
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:Q5H9R7	Human	PMID:18186651
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:Q9UPN7	Human	PMID:18186651
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O15084	Human	PMID:21187329
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O75170	Human	PMID:21187329
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:Q5H9R7	Human	PMID:21187329
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:Q9UPN7	Human	PMID:21187329
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O15084	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O75170	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O75663	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:P78318	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:Q5H9R7	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:Q9UPN7	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:P78318	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O15084	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:O75170	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:P78318	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:Q5H9R7	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:Q9UPN7	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:P78318	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:Q08AM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP6C	IPI	UniProtKB:P78318	Human	PMID:9647778
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PPP6C	IDA		Human	PMID:16716191
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PPP6C	IDA		Human	PMID:32474700
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	Ppp6c	IDA		Mouse	MGI:MGI:6810700|PMID:32474700
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	Ppp6c	IMP		Rat	PMID:8077208|RGD:68293
Cellular Component	GO:0005829	cytosol	PPP6C	IDA		Human	PMID:16716191
Biological Process	GO:0045824	negative regulation of innate immune response	PPP6C	IDA		Human	PMID:32474700
Biological Process	GO:0006470	protein dephosphorylation	PPP6C	IDA		Human	PMID:16716191
Biological Process	GO:0006470	protein dephosphorylation	Ppp6c	IMP		Rat	PMID:8077208|RGD:68293
Biological Process	GO:0001878	response to yeast	ppp6c	IDA		Zfish	PMID:23947337

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern