Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPT1
  • Mouse genes Ppt1
  • Rat genes Ppt1
  • Zfish genes ppt1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppt1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035727	lysophosphatidic acid binding	PPT1	IDA		Human	PMID:18317235
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	PPT1	IDA		Human	PMID:10658183
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	PPT1	IDA		Human	PMID:10737604
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	PPT1	IMP		Human	PMID:7637805
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	Ppt1	IDA		Mouse	PMID:12483688
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:11717424
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:16242638
Molecular Function	GO:0016290	palmitoyl-CoA hydrolase activity	PPT1	IDA		Human	PMID:10658183
Molecular Function	GO:0005515	protein binding	PPT1	IPI	UniProtKB:O14773	Human	PMID:17237713
Molecular Function	GO:0005515	protein binding	PPT1	IPI	UniProtKB:Q3UMW8	Human	PMID:19941651
Molecular Function	GO:0005515	protein binding	PPT1	IPI	UniProtKB:Q76RH3	Human	PMID:25544563
Molecular Function	GO:0005515	protein binding	PPT1	IPI	UniProtKB:O75925	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPT1	IPI	UniProtKB:P26436	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPT1	IPI	UniProtKB:Q3KNS6-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPT1	IPI	UniProtKB:Q6ZR37	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPT1	IPI	UniProtKB:Q8WXF7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPT1	IPI	UniProtKB:Q99932-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPT1	IPI	UniProtKB:Q9Y575-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ppt1	IPI	UniProtKB:Q3UMW8	Mouse	MGI:MGI:5795821|PMID:19941651
Molecular Function	GO:0120146	sulfatide binding	PPT1	IDA		Human	PMID:18317235
Cellular Component	GO:0030424	axon	PPT1	IDA		Human	PMID:12483688
Cellular Component	GO:0030424	axon	Ppt1	IDA		Mouse	PMID:12483688
Cellular Component	GO:0030425	dendrite	Ppt1	IDA		Mouse	PMID:10611498
Cellular Component	GO:0070062	extracellular exosome	PPT1	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	PPT1	IDA		Human	PMID:8895569
Cellular Component	GO:0005615	extracellular space	Ppt1	IDA		Mouse	PMID:9685319
Cellular Component	GO:0005794	Golgi apparatus	PPT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	PPT1	IDA		Human	PMID:7637805
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PPT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005764	lysosome	PPT1	IDA		Human	PMID:11020216
Cellular Component	GO:0005764	lysosome	PPT1	IDA		Human	PMID:19941651
Cellular Component	GO:0005764	lysosome	PPT1	IDA		Human	PMID:8895569
Cellular Component	GO:0005764	lysosome	Ppt1	IDA		Mouse	MGI:MGI:5795821|PMID:19941651
Cellular Component	GO:0005764	lysosome	Ppt1	IDA		Mouse	PMID:9685319
Cellular Component	GO:0005764	lysosome	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:16242638
Cellular Component	GO:0005764	lysosome	Ppt1	IDA		Rat	PMID:10327204|RGD:1581146
Cellular Component	GO:0016020	membrane	PPT1	HDA		Human	PMID:19946888
Cellular Component	GO:0045121	membrane raft	PPT1	IDA		Human	PMID:15929065
Cellular Component	GO:0043005	neuron projection	Ppt1	IDA		Rat	PMID:12270687|RGD:633701
Cellular Component	GO:0043025	neuronal cell body	Ppt1	IDA		Mouse	PMID:10611498
Cellular Component	GO:0043025	neuronal cell body	Ppt1	IDA		Rat	PMID:12270687|RGD:633701
Cellular Component	GO:0005634	nucleus	PPT1	IDA		Human	PMID:10992246
Cellular Component	GO:0045202	synapse	Ppt1	IDA		Rat	PMID:12270687|RGD:633701
Cellular Component	GO:0008021	synaptic vesicle	PPT1	IDA		Human	PMID:12483688
Cellular Component	GO:0008021	synaptic vesicle	Ppt1	IDA		Rat	PMID:12270687|RGD:633701
Biological Process	GO:0008344	adult locomotory behavior	Ppt1	IMP	MGI:MGI:3527191	Mouse	PMID:15649713
Biological Process	GO:0008344	adult locomotory behavior	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:11717424
Biological Process	GO:0008306	associative learning	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:15885820
Biological Process	GO:0007420	brain development	PPT1	IMP		Human	PMID:7637805
Biological Process	GO:0007625	grooming behavior	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:11717424
Biological Process	GO:0016042	lipid catabolic process	PPT1	IDA		Human	PMID:8816748
Biological Process	GO:0007042	lysosomal lumen acidification	PPT1	IMP		Human	PMID:11722572
Biological Process	GO:0007040	lysosome organization	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:16368712
Biological Process	GO:0007040	lysosome organization	Ppt1	IMP	MGI:MGI:3527191	Mouse	PMID:16542649
Biological Process	GO:0009057	macromolecule catabolic process	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:15647513
Biological Process	GO:0031579	membrane raft organization	PPT1	IMP		Human	PMID:15929065
Biological Process	GO:0043066	negative regulation of apoptotic process	PPT1	IDA		Human	PMID:15929065
Biological Process	GO:0030308	negative regulation of cell growth	PPT1	IMP		Human	PMID:10737604
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	PPT1	IMP		Human	PMID:10737604
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	PPT1	IMP		Human	PMID:11020216
Biological Process	GO:0007399	nervous system development	PPT1	IMP		Human	PMID:7637805
Biological Process	GO:0007269	neurotransmitter secretion	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:16242638
Biological Process	GO:0006907	pinocytosis	PPT1	IMP		Human	PMID:16542649
Biological Process	GO:0048549	positive regulation of pinocytosis	PPT1	IMP		Human	PMID:16542649
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	PPT1	IMP		Human	PMID:16542649
Biological Process	GO:0030163	protein catabolic process	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:16368712
Biological Process	GO:0002084	protein depalmitoylation	PPT1	IDA		Human	PMID:10658183
Biological Process	GO:0002084	protein depalmitoylation	PPT1	IDA		Human	PMID:10737604
Biological Process	GO:0002084	protein depalmitoylation	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:16242638
Biological Process	GO:0002084	protein depalmitoylation	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:11717424
Biological Process	GO:0015031	protein transport	PPT1	IMP		Human	PMID:10737604
Biological Process	GO:0006898	receptor-mediated endocytosis	PPT1	IMP		Human	PMID:16542649
Biological Process	GO:0032429	regulation of phospholipase A2 activity	Ppt1	IMP	MGI:MGI:2176390	Mouse	PMID:17341491
Biological Process	GO:0007601	visual perception	Ppt1	IMP	MGI:MGI:3527191	Mouse	PMID:15649713

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern